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4-Thiouridine is a ribonucleoside analog used in RNA analysis and (m)RNA labeling. It inhibits rRNA synthesis and causes a nucleolar stress response. In vitro, 4-thiouridine (0-10 μM) labels and purifies nascent rRNA without significantly affecting rRNA synthesis.
Labels and purifies nascent rRNA.
Inhibits rRNA synthesis.
Causes a nucleolar stress response.
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4 -Thiouridine (1-(4-Thio-beta-D-ribofuranosyl)uracil) is a thio analog of thymidine 4 -Thiouridine can be used to synthesize 4 -thionucleosides with antiviral and anticancer activities 4 -Thiouridine can be used for RNA-sequencing[1][2][3]
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4-Thiouridine is a ribonucleoside analog widely utilized in RNA analysis and (m)RNA labeling. It is known to inhibit rRNA synthesis and induce a nucleolar stress response.
Widely used in RNA analysis and (m)RNA labeling.
Inhibits rRNA synthesis and causes a nucleolar stress response.
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4-Thiouridine 5′-triphosphate tetralithium is a thiolated uridine triphosphate analogue used as a biochemical reagent for incorporation into RNA, cross-linking experiments, and transcriptional labeling. Supplied as the tetralithium salt, it is intended for research applications in molecular biology and nucleotide chemistry.
Used for nucleotide incorporation and transcriptional labeling.
Enables efficient cross-linking for RNA-protein interaction studies.
Provided as the tetralithium salt for improved solubility in aqueous buffers.
Available in small pack sizes suitable for laboratory research.
Characterized by CAS number 20188-72-1 and molecular formula C9H11Li4N2O14P3S.
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2-Thiouracil is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a Ki value of 20 μM. It antagonizes BH4-induced nNOS dimerization and is also known as an antithyroid compound and a highly specific melanoma detector. It has been shown to stimulate the growth of pea and corn root segments.
Significantly reduces the number of nNOS dimers
Inhibits conventional oligomerization of indole
Generates new major products including DHI-TU adducts
Stimulates root growth in pea and corn roots
Rapidly incorporates into tumor pigment in melanoma-bearing mice
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