Thiolactams
Cayman Chemical 5 6-dImethyl-2-ThIouracIl 5g
A heterocyclic building block; has been used in the synthesis of anti-HIV-1 pyrimidinones; has been used as an internal standard for the quantification of thyreostats in bovine plasma
Selleck Chemical LLC 4-Thiouridine-E1292-1G
4-thiouridine (4-Thio-UTP) a thiouridine and a nucleoside analogue has a role as an affinity label and an antimetabolite
Sigma Aldrich Fine Chemicals Biosciences 4-Thiouridine >=98% | 13957-31-8 | MFCD00006538 | 250MG
4-Thiouridine >=98% | Purity: >=98% | Mol Wt: 260.27 | 13957-31-8 | MFCD00006538 | 250MG
Medchemexpress LLC Uridine, 2-thio- | 20235-78-3 | MFCD03788697 | 99.7% | 260.27 g·mol⁻¹ | C9H12N2O5S | 100 MG
2-Thiouridine (uridine, 2-thio-) is a modified nucleoside used in nucleic acid research. It stabilizes U:A base pairs and destabilizes U:G wobble base pairs, improving the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. It has reported in vitro antiviral activity against several positive-sense RNA viruses. Supplied as a high-purity solid for laboratory research use only.
- High purity, typically 99.7%.
- Chemical formula C9H12N2O5S, molecular weight 260.27 g·mol⁻¹.
- Supplied as a 100 MG solid suitable for in vitro studies.
- Used to study base-pairing stability, RNA replication, and antiviral assays.
- Not for human or clinical use; for research use only.
Medchemexpress LLC 4-Thiouridine | 13957-31-8 | 100.0% | 260.27 | 5 MG
4-Thiouridine is a ribonucleoside analog widely used in RNA analysis and (m)RNA labeling. It inhibits rRNA synthesis and causes a nucleolar stress response.
- Ribonucleoside analog
- Used in RNA analysis and (m)RNA labeling
- Inhibits rRNA synthesis
- Causes a nucleolar stress response
- At 0-10 μM, it labels and purifies nascent rRNA without significantly affecting rRNA synthesis
- At ≥50 μM, it strongly inhibits production and processing of rRNA
Selleck Chemical LLC 4-Thiouridine-E1292-25MG
4-thiouridine (4-Thio-UTP) a thiouridine and a nucleoside analogue has a role as an affinity label and an antimetabolite
Medchemexpress LLC Uridine,4-thio- | 13957-31-8 | 99.98% | 260.27 | 1 ML
4-Thiouridine is a ribonucleoside analog widely used in RNA analysis and (m)RNA labeling. It works by inhibiting rRNA synthesis, which leads to a nucleolar stress response. It is intended for research use only and is not sold to patients.
- Ribonucleoside analog
- Used in RNA analysis and mRNA labeling
- Inhibits rRNA synthesis
- Causes a nucleolar stress response
- High purity: 99.98%
- Labels and purifies nascent rRNA at 0-10 μM
- Strongly inhibits rRNA production and processing at ≥50 μM
Cayman Chemical 5 6-dImethyl-2-ThIouracIl 1g
A heterocyclic building block; has been used in the synthesis of anti-HIV-1 pyrimidinones; has been used as an internal standard for the quantification of thyreostats in bovine plasma
Medchemexpress LLC 4-Thiouracil | 591-28-6 | 99.98% | 128.15 | 100 MG
4-Thiouracil is a thionucleobase possessing cytostatic properties. It functions as a biological photoprobe for detecting RNA structures and nucleic acid-nucleic acid contacts. Additionally, it serves as a potent ultraviolet A (UVA) photosensitizer, generating reactive oxygen species (O2). 4-Thiouracil holds promise for research in photocrosslinking, photodamage, and photodynamic therapy.
- Thionucleobase with cytostatic properties.
- Can be used as biological photoprobes to detect RNA structures and nucleic acid-nucleic acid contacts.
- Acts as a strong UVA photosensitizer, providing a source of reactive oxygen species (O2).
- Promising for research in photocrosslinking, photodamage, and photodynamic therapy.
Medchemexpress LLC 4-Thiouridine 5'-triphosphate tetralithium | 20188-72-1 | C9H11Li4N2O14P3S | 25 MG
4-Thiouridine 5'-triphosphate tetralithium (4-Thio-UTP tetralithium) is a UTP analog and a potent P2Y2 and P2Y4 agonist, with EC50 values of 35 nM for hP2Y2 and 350 nM for hP2Y4. This laboratory chemical is suitable for cross-linking experiments and transcriptional complex labeling studies. It is for research use only and has not been fully validated for medical applications.
- Potent P2Y2 and P2Y4 agonist
- EC50 values of 35 nM for hP2Y2 and 350 nM for hP2Y4
- Suitable for cross-linking experiments
- Useful in transcriptional complex labeling studies
Apexbio Technology LLC 2-Thiouracil 141-90-2 5g
2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings
Apexbio Technology LLC 2-Thiouracil 141-90-2 1g
2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings
eMolecules Broadpharm / 2-Thiouridine / 100mg / 761707707 / BP-58834 / 98.000 / 20235-78-3 / MFCD03788697 / 260.260 / C9H12N2O5S
Broadpharm / 2-Thiouridine / 100mg / 761707707 / BP-58834 / 98.000 / 20235-78-3 / MFCD03788697 / 260.260 / C9H12N2O5S
Medchemexpress LLC 2-Thiouracil | 141-90-2 | 99.9% | 1 G
2-Thiouracil is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a Ki value of 20 μM. It antagonizes BH4-induced nNOS dimerization. Additionally, it is an antithyroid compound and a highly specific melanoma detector. It also stimulates the growth of pea and corn root segments.
- Selective neuronal nitric oxide synthase (nNOS) inhibitor
- Antagonizes BH4-induced nNOS dimerization
- Antithyroid compound
- Highly specific melanoma detector
- Stimulates the growth of pea and corn root segments
Medchemexpress LLC 2-Thiouracil | 141-90-2 | 99.9% | 5 G
2-Thiouracil (Thiouracil) is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a Ki value of 20 μM. It antagonizes BH4-induced nNOS dimerization and has been observed to stimulate the growth of pea and corn root segments. Additionally, it functions as an antithyroid compound and a highly specific melanoma detector.
- Functions as a selective neuronal nitric oxide synthase (nNOS) inhibitor
- Antagonizes BH4-induced nNOS dimerization
- Acts as an antithyroid compound
- Serves as a highly specific melanoma detector
- Stimulates growth of pea and corn root segments