Thiophenes
Apexbio Technology LLC Quinacrine 2HCl 69-05-6 10mM (in 1mL H2O)
Quinacrine 2HCl (69-05-6) is an orally active small-molecule inhibitor targeting the NF- B signaling pathway It is designed to inhibit the NF- B cascade thereby downregulating pro-survival gene expression and promoting apoptotic pathways in tumor cells Quinacrine 2HCl exerts its biological activity primarily through inhibition of NF- B and activation of the p53-dependent apoptotic pathway In in vitro studies Quinacrine 2HCl demonstrates growth inhibition of multiple cancer cell lines with reported IC50 values generally in the low micromolar range depending on the specific cell model and experimental context Based on these pharmacological properties Quinacrine 2HCl holds research potential in investigating apoptosis regulatory mechanisms NF- B pathway involvement in cancer biology and preclinical evaluation of potential anticancer therapies
Apexbio Technology LLC Pramipexole 2HCl Monohydrate 191217-81-9 10mM (in 1mL DMSO)
Pramipexole 2HCl Monohydrate is a synthetic non-ergoline dopamine receptor agonist targeting dopamine receptor subtypes particularly D3 D2S D2L and D4 It is designed to activate these receptors thereby modulating dopaminergic transmission pathways Pramipexole 2HCl Monohydrate exerts its biological activity primarily through selective receptor activation Based on these pharmacological properties Pramipexole 2HCl Monohydrate holds research potential in studies of receptor-ligand interactions receptor subtype functional analysis and dopamine-related neurologic or psychiatric disorders including Parkinson s disease and restless legs syndrome
Apexbio Technology LLC Pramipexole 2HCl Monohydrate 191217-81-9 50mg
Pramipexole 2HCl Monohydrate is a synthetic non-ergoline dopamine receptor agonist targeting dopamine receptor subtypes particularly D3 D2S D2L and D4 It is designed to activate these receptors thereby modulating dopaminergic transmission pathways Pramipexole 2HCl Monohydrate exerts its biological activity primarily through selective receptor activation Based on these pharmacological properties Pramipexole 2HCl Monohydrate holds research potential in studies of receptor-ligand interactions receptor subtype functional analysis and dopamine-related neurologic or psychiatric disorders including Parkinson s disease and restless legs syndrome
Medchemexpress LLC Sulfo-Cy5 hydrazide | 2055138-61-7 | 96.4% | 656.81 | C32H40N4O7S2 | 10 MG
Sulfo-Cy5 hydrazide is a water-soluble, near-infrared fluorescent dye containing a hydrazide functional group for conjugation to aldehydes and ketones. It is optimized for imaging and fluorescence detection with excitation/emission maxima near 646/662 nm.
- Near-infrared excitation and emission (646/662 nm).
- Hydrazide reactive group for labeling aldehydes and ketones.
- Water-soluble due to sulfonate groups, facilitating aqueous labeling reactions.
- Solid form, light yellow to brown, high reported purity (96.39%).
- Suitable for biomolecule labeling and fluorescence imaging applications.
Medchemexpress LLC 1-(dibenzylamino)-3-(4-(trifluoromethyl)phenoxy)propan-2-ol | 2222094-18-8 | 99.7% | C24H24F3NO2 | 10MG
BC1618 is a small-molecule research compound that inhibits Fbxo48 and stimulates AMPK-dependent signaling by preventing pAMPKα degradation. It is used in preclinical studies of mitophagy, mitochondrial dynamics, and metabolic regulation.
- Orally active tool compound suitable for in vivo studies.
- Stimulates AMPK-dependent signaling by preventing pAMPKα degradation.
- Facilitates research into mitophagy, mitochondrial fission, and insulin sensitivity.
- High reported purity for reliable experimental results.
- Soluble in DMSO, insoluble in water, enabling formulation flexibility.
- Available in small quantities suitable for biochemical and animal studies.
Medchemexpress LLC Bisantrene dihydrochloride | 71439-68-4 | 98.9% | 471.39 g/mol | C22H24Cl2N8 | 25 MG
Bisantrene dihydrochloride is a research-grade antitumor compound that intercalates DNA and inhibits eukaryotic type II topoisomerases. Supplied as a solid for in vitro and preclinical research, it is used in cancer biology and pharmacology studies for mechanistic and efficacy assays.
- High purity (98.85%) suitable for research use.
- Confirmed molecular weight 471.39 g/mol and formula C22H24Cl2N8.
- Available in multiple pack sizes, including 25 MG quantities.
- Soluble in DMSO and water with recommended preparation procedures.
- Store sealed and protect from moisture; observe solvent storage temperature guidelines.
Medchemexpress LLC Cutamesine dihydrochloride | 165377-44-6 | MFCD00939308 | 98.1% | 441.43 g/mol | C23H34Cl2N2O2 | 5 MG
Cutamesine dihydrochloride is a selective sigma-1 (σ1) receptor agonist supplied as the dihydrochloride salt for research use. It is provided as a solid with reported purity of ~98% and a molecular weight of 441.43 g/mol. The compound is used in neuroscience and pharmacology studies to probe sigma-1 receptor activity and downstream signaling pathways.
- Selective sigma-1 receptor agonist for receptor pharmacology studies.
- High purity suitable for research applications.
- Supplied as a solid with reported solubility in DMSO and water.
- Available in small pack sizes appropriate for screening and assay work.
- Applicable to in vitro and ex vivo neuroscience models.
Medchemexpress LLC Chroman 1 dihydrochloride | 1273579-40-0 | MFCD23098792 | 99.1% | 509.43 | C24H30Cl2N4O4 | 10 MG
Chroman 1 dihydrochloride is a highly potent and selective Rho-associated protein kinase (ROCK) inhibitor, with markedly greater activity against ROCK2 than ROCK1. Supplied as a dihydrochloride solid salt with high purity and good solubility, it is used in biochemical and cellular studies to probe ROCK signaling pathways.
- Highly potent, selective ROCK2 inhibitor (IC50 1 pM).
- Also inhibits ROCK1 and MRCK (IC50 52 pM and 150 nM).
- High purity: 99.11%.
- Soluble in water and DMSO: 100 mg/mL.
- Supplied as a solid dihydrochloride salt for stability.
- Recommended storage: sealed and away from moisture; in solvent: -80°C (6 months), -20°C (1 month).