Carboximidamides
Medchemexpress LLC DNA antisense oligonucleotide (Tofersen) with 2'-O-(2-methoxyethyl) modifications | 2088232-70-4 | 95.5% | 7128.00 | C230H317N72O123P19S15 | 5 MG
Tofersen is an antisense oligonucleotide that reduces synthesis of superoxide dismutase 1 (SOD1) protein via RNase H-dependent degradation of SOD1 mRNA. It is supplied as a purified, sequence-modified oligonucleotide for laboratory research, primarily in studies related to amyotrophic lateral sclerosis (ALS).
- Antisense mechanism mediating RNase H-dependent degradation of SOD1 mRNA.
- Suitable for ALS-related research applications.
- Provided as a purified oligonucleotide with documented purity and molecular weight.
- Sequence modified with 2'-O-(2-methoxyethyl) groups for increased stability.
- Available in small-mass quantities appropriate for experimental use.
- Certificate of analysis available for batch verification.
Medchemexpress LLC Creatine phosphokinase, rabbit muscle (CPK) | 9001-15-4 | 1 KU
Creatine phosphokinase, rabbit muscle (CPK) catalyzes the reversible reaction of creatine and ATP to form phosphocreatine and ADP. This enzyme is crucial for maintaining a constant ATP/ADP ratio during rapid energy turnover.
- Catalyzes reversible reaction of creatine and ATP
- Forms phosphocreatine and ADP
- Key enzyme for maintaining constant ATP/ADP ratio
- Appearance: solid
- Color: white to off-white
- Enzyme activity: ≥100 U/mg solid
- Unit definition: amount of enzyme that transfers 1.0 μmole of phosphate from phosphocreatine to ADP per min at pH 7.4 at 30°C
- Solubility: can be dissolved and stored at 1 mg/ml using 20 mM Tris (pH 8.0)
- Avoids repeated freezing and thawing
- Recommended to add 0.1% albumin to reaction buffer when diluting to avoid inactivation
Medchemexpress LLC AN0128, a boron-containing antibacterial and anti-inflammatory agent | 872044-70-7 | 99.0% | 400.06 | 100 MG
AN0128, a boron-containing antibacterial and anti-inflammatory agent | 872044-70-7 | 99.0% | 400.06 | 100 MG
Medchemexpress LLC Parishin C | 174972-80-6 | MFCD29059903 | 99.8% | 728.65 g·mol^-1 | C32H40O19 | 10 MG
Parishin C is a parishin derivative isolated from Gastrodia elata and supplied as a high-purity analytical standard for research and analytical applications. It may exhibit antioxidant properties.
- High purity of 99.8%.
- Molecular formula C32H40O19 and molecular weight 728.65 g·mol^-1.
- Supplied as a 10 MG vial for analytical use.
- Intended for research and analytical assays, including biochemical characterization and reference standard use.
- Isolated from Gastrodia elata and reported to have antioxidant activity.
Sigma Aldrich Fine Chemicals Biosciences Agar ash 2.0 4.55KG
Agar is a polysaccharide consisting of - D-galactopyranosyl and 3 6-anhydro -L- galactopyranosyl units. Depending on the source agar exists as various substituted forms such as methyl and sulphate ether. It is a linear galactan polysaccharide isolated from the cell wall of Rhodophyceae class of seaweeds.
Medchemexpress LLC Guanidine, N-methyl-, hydrochloride (1:1) | 21770-81-0 | 109.56 | 10 G
1-Methylguanidine monohydrochloride is an endogenous metabolite for research applications. This compound presents as a white to off-white solid with a high purity of 98.0%. It is suitable for various research fields including metabolic disease and as a reference standard.
- Endogenous metabolite
- High purity of 98.0%
- Appears as a white to off-white solid
- Store at 4°C, sealed, away from moisture
- Stock solutions in solvent can be stored at -80°C for 6 months or -20°C for 1 month
- Soluble in water and PBS
Medchemexpress LLC Allantoin | 97-59-6 | MFCD00005260 | 158.12 | 5 G
Allantoin is a widely recognized skin conditioning agent that supports healthy skin and stimulates new tissue growth. It exhibits anti-oxidative and anti-inflammatory properties, and has been observed to attenuate apoptosis and cytotoxicity, enhancing the viability of STZ-induced β-cells in a dose-dependent manner. Additionally, allantoin decreases caspase-3 levels, boosts phosphorylated B-cell lymphoma 2 (Bcl-2) expression, and activates imidazoline 3 (I3) receptors.
- Skin conditioning agent
- Promotes healthy skin and new tissue growth
- Exhibits anti-oxidative and anti-inflammatory activities
- Attenuates apoptosis and cytotoxicity
- Increases viability of STZ-induced β-cells
- Activates imidazoline 3 (I3) receptors
STA Pharmaceutical ANA 2'-F U amidite | 1 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 30 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 47.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
Medchemexpress LLC Creatine (standard) | 57-00-1 | 99.98% | 131.13 | 250 MG
Creatine (Standard) is the analytical standard of Creatine, intended for research and analytical applications. Creatine is an endogenous amino acid derivative that plays an important role in cellular energy, particularly in muscle and brain.
- Analytical standard for Creatine.
- Intended for research and analytical applications.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Endogenous metabolite.
- Formula: C4H9N3O2.
- Appearance: Solid, white to off-white.
- Structure classification: Amino acids.
- Initial source: Endogenous metabolite, Disease markers (Cancer, Nervous System Disorder), Human Gut Microbiota Metabolites.
Medchemexpress LLC 5'-Phosphoguanylyl-(3',5')-guanosine | 33008-99-0 | MFCD00064360 | 95.8% | 708.43 g/mol | C20H26N10O15P2 | 5 MG
5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is a nucleotide intermediate produced during enzymatic degradation of cyclic di-guanylate (c-di-GMP). It is supplied as a purified research reagent for biochemical and microbiology studies involving nucleotide signaling and enzymology.
- Purity 95.8% suitable for analytical and biochemical assays.
- Molecular weight 708.43 g/mol.
- Chemical formula C20H26N10O15P2.
- Available in milligram scales (5 mg, 10 mg, 25 mg, 50 mg, and larger sizes).
- Intended for biochemical assays and studies of nucleotide signaling and c-di-GMP metabolism.
- Provided with characterization data to support research use.
Medchemexpress LLC Ccr4-351 | 2174938-70-4 | MFCD32701932 | 99.0% | 500.42 g/mol | C24H27Cl2N7O | 5 MG
CCR4-351 is a small-molecule, orally active CCR4 antagonist used for preclinical research. It shows potent and selective activity in cellular assays and has demonstrated antitumor efficacy in animal models. For research use only; consult the supplier datasheet and safety documents for handling, storage, and dosing guidance.
- Orally active and selective CCR4 antagonist.
- Demonstrated antitumor activity in vivo.
- Potent activity in cellular assays (low-nanomolar IC50 reported).
- High chemical purity suitable for research applications.
- Provided as a solid form for in vitro and in vivo studies.
- Refer to the product datasheet and safety documents for handling and dosing.
Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 g/mol | C21H26ClN | 50 MG
Melitracen hydrochloride is the hydrochloride salt of melitracen, supplied as a high-purity research standard for analytical, pharmacological, and formulation studies. It is a white to off-white solid (CAS 10563-70-9) with defined solubility and storage recommendations to support reproducible results.
- High purity suitable for analytical and pharmacological research.
- White to off-white solid with consistent physical properties.
- Soluble in water and DMSO; may require sonication.
- Store solid at 4°C, sealed and protected from moisture; solutions at -80°C (long term) or -20°C (short term).
- Supplied in small pack sizes convenient for assay and preclinical work.
Sigma Aldrich Fine Chemicals Biosciences Creatine phosphate
Creatine kinase is responsible for the production of ATP (adenosine triphosphate) by transferring phosphate from creatine phosphate to ADP (adenosine diphosphate). Creatine phosphate is provided as a disodium salt.
eMolecules 108-19-0 | Biuret | Combi-Blocks | MFCD00007946 | 103.081 | C2H5N3O2 | 98.000 | NC(=O)NC(N)=O | 5g | 296394882
Biuret | Combi-Blocks | 108-19-0 | MFCD00007946 | 103.081 | C2H5N3O2 | 98.000 | NC(=O)NC(N)=O | 5g | 296394882
Sigma Aldrich Fine Chemicals Biosciences Cimetidine | 51481-61-9 | MFCD00133296 | 5g
Cimetidine | Mol Wt: 252.34 | 51481-61-9 | MFCD00133296 | 5g