Carboximidamides
AdipoGen Diphenyliodonium PF6
Chemical. CAS 58109-40-3. Formula C12H10F6IP. MW 426.08. Synthetic. Catalyst for the photochemical polymerization of various monomers.
eMolecules 872044-70-7 | Medchem Express | AN0128 | 5mg | 705860157 | HY-10979 | MFCD18251581 | 400.06 | C20H16BCl2NO3
Medchem Express | AN0128 | 5mg | 705860157 | HY-10979 | 872044-70-7 | MFCD18251581 | 400.060 | C20H16BCl2NO3
Medchemexpress LLC Bnc375 | 1557240-80-8 | 99.6% | 394.92 g/mol | C19H23ClN2O3S | 5 MG
BNC375 is a small-molecule, orally available type I positive allosteric modulator of the α7 nicotinic acetylcholine receptor (α7 nAChR). It demonstrates an EC50 of about 1.9 μM and exhibits CNS drug-like properties, supplied as a high-purity research chemical for in vitro and in vivo pharmacology studies.
- Potent, selective type I positive allosteric modulator of α7 nAChR.
- EC50 approximately 1.9 μM in functional assays.
- High purity suitable for in vitro and in vivo studies.
- Soluble in DMSO; recommended in vivo formulations provided.
- Available in milligram-scale quantities for research use.
- Storage recommendations provided to maintain stability.
Sigma Aldrich Fine Chemicals Biosciences Nalpha Tosyl L lysne chlo500MG
Nalpha Tosyl L lysne chlo500MG
eMolecules 134865-70-6 | Medchem Express | 8-M-PDOT | 5mg | 752822498 | HY-101358 | MFCD00901636 | 233.311 | C14H19NO2
ChemScene | (S)-1-(m-Tolyl)ethanamine hydrochloride | 100mg | 632322474 | CS-0153235 | 1630984-18-7 | MFCD11101252 | 171.670 | C9H14ClN
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Medchemexpress LLC ATX inhibitor 1 | 2225892-70-4 | 99.3% | 501.30 | 10 MM 1 ML
ATX inhibitor 1 is a potent ATX inhibitor, with IC50 values of 1.23 nM (FS-3) and 2.18 nM (bis-pNPP). It is supplied as a white to off-white solid.
- Potent ATX inhibitor
- Molecular weight of 501.30
- Store at -20°C for up to 3 years as powder
- Soluble in DMSO (250 mg/mL)
Medchemexpress LLC H3B-6545 | 2052130-80-8 | 99.4% | 567.58 | 10 MG
H3B-6545 is an oral, selective estrogen receptor covalent antagonist (SERCA) for the research of metastatic ER-positive, HER2-negative breast cancer. It is a first-in-class selective ER covalent antagonist (SERCA) that inactivates both wild-type and mutant ERα by targeting C530 and enforcing a unique antagonist conformation.
- Inactivates wild-type and mutant ERα by targeting C530.
- Enforces a unique antagonist conformation.
- Used for research of metastatic ER-positive, HER2-negative breast cancer.
- Shows potent activity in MCF-7 xenograft model.
- Well tolerated in rats and monkeys across a broad dose range.
eMolecules 1399191-70-8 | Ambeed | 55-(14-Phenylene)dipicolinaldehyde | 100mg | 603089926 | A1226399 | 288.306 | C18H12N2O2
Medchem Express | SB 242084 | 5mg | 446262835 | HY-13409 | 181632-25-7 | MFCD05662310 | 394.860 | C21H19ClN4O2
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Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 | C21H26ClN | 10 MG
Melitracen hydrochloride is a tricyclic antidepressant research compound supplied as the hydrochloride salt and used as a chemically characterized reference for laboratory studies. It inhibits norepinephrine and serotonin uptake and is provided in small, labeled packs for analytical and formulation work.
- High chemical purity (reported ~99.8%) for analytical applications.
- Hydrochloride salt form for consistent physicochemical properties.
- Molecular weight 327.89 and molecular formula C21H26ClN.
- Available in multiple small pack sizes suitable for research and testing.
- Supplied with product documentation and batch information.
Medchemexpress LLC Pentagamavunon-1 (PGV-1) | 27060-70-4 | 98.95% | 348.43 | 100 MG
Pentagamavunon-1 (PGV-1) is a Curcumin analog with oral activity. It targets multiple molecular mechanisms to induce apoptosis, including the inhibition of angiogenic factors cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF). PGV-1 also inhibits NF-κB activation.
- Enhances the cytotoxic effect of 5-FU on WiDr cells
- Induces G2/M arrest
- Exhibits significant anti-tumor activity in a PDX model
- Shows minimal adverse effects on normal cells
- Soluble in DMSO for in vitro studies
- Soluble in 10% DMSO and 90% (20% SBE-β-CD in saline) for in vivo studies
- Soluble in 10% DMSO and 90% corn oil for in vivo studies
Medchemexpress LLC Creatine-13C | 687996-99-2 | 98.5% | 132.13 | 25 MG
Creatine-13C is a 13C labeled Creatine, which is an endogenous amino acid derivative. It plays a significant role in cellular energy, particularly in muscle and brain. It is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
- Stable heavy isotope of carbon (13C) incorporated into the molecule.
Medchemexpress LLC Clonidine (hydrochloride) | 4205-91-8 | 99.9% | 1 G
Clonidine hydrochloride is an agonist of α2-adrenoceptor and a potent antihypertensive agent. It has been studied for its various biological activities.
- Induces CGRP (α and β) mRNA expression in endothelial cells
- Increases NO levels in endothelial cells
- Decreases rat body temperature
- Suppresses dopamine efflux in the prefrontal cortex
- Reduces blood pressure
- Enhances RVLM pERK1/2
Medchemexpress LLC Ripk3-in-1 | 2361139-70-8 | 99.3% | 50 MG
RIPK3-IN-1 is a type II DFG-out inhibitor with primary activity against RIPK3. It also demonstrates inhibitory effects on RIPK1, RIPK2, and c-Met kinase. Additionally, it inhibits ABL, BRAF/V599E, MAP4K3, and SRC kinases.
- Inhibits RIPK3 with an IC50 of 9.1 nM
- Inhibits RIPK1 with an IC50 of 5.5 μM
- Inhibits RIPK2 with an IC50 of >10 μM
- Inhibits c-Met kinase with an IC50 of 1.1 μM
- Inhibits ABL with an IC50 of 0.37 μM
- Inhibits BRAF/V599E with an IC50 of 0.15 μM
- Inhibits MAP4K3 with an IC50 of 0.012 μM
- Inhibits SRC with an IC50 of 0.075 μM