Enamines
Accela Chembio Inc Isopropyl 3-aminocrotonate | 100g | 14205-46-0 | MFCD00134272 | 97+% | Shelf Life: 1260 Days | Light Sensitive/+4
Isopropyl 3-aminocrotonate | 100g | 14205-46-0 | MFCD00134272 | 97+% | Shelf Life: 1260 Days | Light Sensitive/+4
Medchemexpress LLC CDK2-IN-4 | 1316652-41-1 | 99.3% | 326.37 g/mol | C16H14N4O2S | 5 MG
NCC-149 is a selective histone deacetylase 8 (HDAC8) inhibitor used in cell biology research, including studies of neural differentiation. The product is provided with supporting documentation for purity, handling, and storage, and is available both as a solid and as a DMSO solution.
- Selective HDAC8 inhibitor for neural differentiation studies.
- Documented purity approximately 99.3% based on certificate of analysis.
- Available as a solid and as a 10 mM solution in DMSO.
- Datasheet, certificate of analysis, and safety data sheet provided for quality and safety information.
- Storage recommendations included for powdered material and solutions.
Medchemexpress LLC PF-562271 besylate | 939791-38-5 | MFCD14105612 | 99.2% | 665.66 | C27H26F3N7O6S2 | 50 MG
PF-562271 besylate is the besylate salt of a potent, ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and Pyk2 commonly used in preclinical biochemical and cellular research. It shows low-nanomolar activity against FAK and is supplied at high purity in small-scale packages for laboratory studies.
- Potent ATP-competitive inhibitor of FAK and Pyk2 (FAK IC50 ≈ 1.5 nM; Pyk2 IC50 ≈ 13 nM).
- Reversible mechanism suitable for biochemical assays.
- High purity for research applications (reported ~99.17%).
- Available in multiple small-scale package sizes for laboratory use.
- Suitable for cellular and signaling pathway studies.
TARGETMOL CHEMICALS INC Cisatracurium besylate 50MG
Also available in 1 mL, 10 mg, 25 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Cisatracurium besylate (51W89) is a nondepolarizing skeletal muscle relaxant intended for intravenous administration. Purity 98%
eMolecules 39741-62-3 | tert-butyl (2S)-2,5-diamino-5-oxopentanoate hydrochloride | Synthonix - Stock | MFCD00039081 | 238.710 | C9H19ClN2O3 | 95.000 | Cl.CC(C)(C)OC(=O)[C@@H](N)CCC(N)=O | 25g | 495874754
tert-butyl (2S)-2,5-diamino-5-oxopentanoate hydrochloride | Synthonix - Stock | 39741-62-3 | MFCD00039081 | 238.710 | C9H19ClN2O3 | 95.000 | Cl.CC(C)(C)OC(=O)[C@@H](N)CCC(N)=O | 25g | 495874754
Medchemexpress LLC Molibresib (besylate) | 1895049-20-3 | 97.0% | 50 MG
Molibresib besylate is an orally active pan-BET inhibitor that targets BRD2, BRD3, BRD4, and BRDT. It disrupts the interaction between BET proteins and chromatin, inhibiting MYC expression and target gene transcription. This compound exhibits broad antiproliferative activity, inhibiting cancer cell growth and inducing growth arrest. It is widely applicable to research related to acute myeloid leukemia, multiple myeloma, triple-negative breast cancer, small-cell lung cancer, and various advanced refractory solid tumors.
- Orally active pan-BET inhibitor.
- Targets BRD2, BRD3, BRD4, and BRDT.
- Inhibits MYC expression and target gene transcription.
- Exhibits broad antiproliferative activity.
- Shows synergistic effect with MEK inhibitors.
- Applicable for research in acute myeloid leukemia, multiple myeloma, triple-negative breast cancer, and small-cell lung cancer.
Medchemexpress LLC 4-((((1-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethyl)-1h-1, | 98.4% | 795.72 | 5 MG
TO-1187 TFA is a selective HDAC6 PROTAC degrader with a DC50 of 5.81 nM. It promotes the ubiquitination and degradation of HDAC6 and is used in the study of hematological malignancies and solid tumors. The compound is composed of an HDAC6 ligand, a CRBN ligase ligand, and a linker.
- Selective PROTAC degrader
- Promotes ubiquitination and degradation of HDAC6
- Applicable for studying hematological malignancies and solid tumors
Selleck Chemical LLC Nimodipine S1747-1g
Nimodipine (BAY E 9736) is a dihydropyridine calcium channel blocker and an autophagy inhibitor used in the treatment of high blood pressure
eMolecules 14205-39-1 | Methyl 3-aminocrotonate | Chem-Impex115.132 | C5H9NO2 | 98.000 | COC(=O)C=C(C)N | 25g | 386901549
Methyl 3-aminocrotonate | Chem-Impex | 14205-39-1115.132 | C5H9NO2 | 98.000 | COC(=O)C=C(C)N | 25g | 386901549
Medchemexpress LLC PF-562271 besylate | 939791-38-5 | MFCD16038299 | 99.2% | 665.66 g·mol⁻¹ | C27H26F3N7O6S2 | 5 MG
PF-562271 besylate is a small-molecule, ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and Pyk2 used in research to study FAK pathway modulation. It is supplied as the besylate salt for laboratory use and has been evaluated in preclinical and clinical studies.
- Potent ATP-competitive inhibitor of FAK and Pyk2 (IC50 1.5 nM and 13 nM).
- Reversible mechanism suitable for biochemical and cellular assays.
- Supplied as besylate salt for improved stability and handling.
- High chemical purity (99.17%) for reproducible results.
- Molecular weight 665.66 g·mol⁻¹, molecular formula C27H26F3N7O6S2.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC TO-1187 (TFA) | 98.4% | 795.72 | C36H36F3N9O9 | 10 MG
TO-1187 TFA is a selective PROTAC degrader that targets HDAC6 and recruits cereblon to promote ubiquitination and proteasomal degradation of HDAC6. Supplied as a trifluoroacetic acid salt in solid form, it is intended as a research tool for cellular and preclinical studies investigating HDAC6 biology and PROTAC-mediated target removal.
- Selective HDAC6 degrader with DC50 of 5.81 nM.
- Engages cereblon to induce ubiquitination and proteasomal degradation.
- High chemical purity (98.4%) suitable for biochemical and cellular assays.
- Provided as a solid TFA salt for stable handling and storage.
- Includes analytical documentation such as COA, H NMR, LCMS, and RP-HPLC.
- Storage recommended at 4°C under nitrogen; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC PF-562271 besylate | 939791-38-5 | MFCD14105612 | 99.2% | 665.66 | C27H26F3N7O6S2 | 10 MG
PF-562271 besylate is the besylate salt of PF-562271, a potent ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and Pyk2 used in cancer research to probe signaling pathways, tumor growth, and cell adhesion. The compound is supplied as a high-purity solid for in vitro and in vivo studies.
- Potent inhibition of FAK and Pyk2 (FAK IC50 ~1.5 nM; Pyk2 IC50 ~13 nM).
- High reported purity (99.17%).
- Provided as a solid, off-white to light-yellow material suitable for handling and formulation.
- Demonstrated antiproliferative activity in multiple human cell lines.
- Used for in vitro and in vivo studies of tumor growth, signaling, and angiogenesis.
- Available in a 10 mg package for research use.
Medchemexpress LLC (R)-Nimodipine | 77940-92-2 | 99.87% | 100 MG
(R)-Nimodipine is an orally active, blood-brain barrier-permeable L-type calcium channel blocker with an IC50 of 5 nM. It inhibits corticosterone release by blocking calcium channels on the hypothalamic-pituitary-adrenal axis, which can reverse immobilization stress-induced memory impairment and behavioral abnormalities. It is for research use only.
- Inhibits corticosterone release
- Reverses immobilization stress-induced memory impairment
- Used in studies related to aneurysmal subarachnoid hemorrhage
- Used in studies related to cerebral ischemia
- Used in studies related to epilepsy
- Used in studies related to age-related degenerative neurological diseases
- Used in studies related to alcohol intoxication