Guanidines
Selleck Chemical LLC Metformin
Metformin (1 1-Dimethylbiguanide) a widely used drug for treatment of type 2 diabetes activates AMP-activated protein kinase (AMPK) in hepatocytes Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
Medchemexpress LLC Phenylbiguanide hydrochloride | 55-57-2 | 100.0% | 213.67 g/mol | C8H12ClN5 | 1 ML
Phenylbiguanide hydrochloride is a research-grade 5-HT3 receptor selective agonist used in receptor pharmacology and electrophysiology. It is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and in solid forms for preparation. CAS number 55-57-2; reported EC50 ≈ 3.0 ± 0.1 μM.
- Selective 5-HT3 receptor agonist with an EC50 of 3.0 ± 0.1 μM.
- Ready-to-use 10 mM solution in DMSO for in vitro assays.
- High purity suitable for research applications.
- Molecular weight 213.67 g/mol; molecular formula C8H12ClN5.
- Formulation and solubility guidance provided for in vitro and in vivo studies.
Accela Chembio Inc 1 | 1-dimethylbiguanide Hydrochloride | 100g | 1115-70-4 | MFCD00012582 | 96% | Shelf Life: 2340 Days | Light Sensitive/moisture Sensitive
1 | 1-dimethylbiguanide Hydrochloride | 100g | 1115-70-4 | MFCD00012582 | 96% | Shelf Life: 2340 Days | Light Sensitive/moisture Sensitive
Medchemexpress LLC Biguanide | 56-03-1 | 98.1% | 10 MG
Biguanide (CAS 56-03-1) is a small-molecule biguanide base used as a research reagent. It is reported to inhibit mitochondrial ATP production, activate the LKB1-AMPK signaling pathway, and modulate insulin-receptor signaling; it is commonly used in metabolic and diabetes-related studies.
- Small-molecule biguanide reagent for research use
- CAS number 56-03-1
- Molecular formula C2H7N5; molecular weight 101.11 g/mol
- Reported to inhibit mitochondrial ATP production and activate AMPK signaling
- Used in metabolic, insulin signaling, and mitochondrial studies
- Available in a 10 MG vial; verify pack sizes with supplier
Apexbio Technology LLC Metformin 657-24-9 10mg
Metformin (CAS 657-24-9) is a biguanide compound widely employed as an antihyperglycemic agent in type II diabetes research Its primary mechanism involves enhancing insulin sensitivity in peripheral tissues and reducing hepatic gluconeogenesis leading to lower circulating glucose levels without directly inducing hypoglycemia Metformin is also associated with decreased fasting plasma insulin concentrations and modest weight reduction These properties make it a valuable small molecule for investigating metabolic regulation insulin resistance and therapeutic strategies for obesity-associated metabolic disorders in preclinical and clinical studies
Apexbio Technology LLC Metformin 657-24-9 25mg
Metformin (CAS 657-24-9) is a biguanide compound widely employed as an antihyperglycemic agent in type II diabetes research Its primary mechanism involves enhancing insulin sensitivity in peripheral tissues and reducing hepatic gluconeogenesis leading to lower circulating glucose levels without directly inducing hypoglycemia Metformin is also associated with decreased fasting plasma insulin concentrations and modest weight reduction These properties make it a valuable small molecule for investigating metabolic regulation insulin resistance and therapeutic strategies for obesity-associated metabolic disorders in preclinical and clinical studies
Medchemexpress LLC Metformin hydrochloride | 1115-70-4 | MFCD00012582 | 100.0% | 165.62 | C4H12ClN5 | 10 MG
Metformin hydrochloride is the hydrochloride salt of metformin supplied as an analytical reference standard for use in analytical chemistry, method development, and research. It is identified by CAS 1115-70-4, has formula C4H12ClN5, and a molecular weight of 165.62.
- High purity suitable for analytical assays (reported 99.97%).
- Provided as a 10 MG package for calibration and method development.
- Highly soluble in water and PBS (≥100 mg/mL); limited solubility in DMSO.
- Storage: keep sealed at 4°C; follow solvent storage guidelines for long-term stability.
- Intended for use as an analytical reference in validation, quality control, and research workflows.
Selleck Chemical LLC Metformin HCl S1950-5g
Metformin HCl (1 1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis) Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
Med Vet International Metformin Hcl 500mg, 100 Tablets
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Metformin HCL 500mg, 100 Tablets