Organic nitroso compounds
Cayman Chemical N-NItroso-N-ethylnIlIn 25mg
An N-nitrosamine; non-carcinogenic in a survival assay using 2FR450 Rauscher leukemia virus-infected rat embryo cultures; a synthetic intermediate in the synthesis of 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as CXCR2 antagonists
Cayman Chemical N-NItroso-N-methylnIlIn 100mg
An N-nitrosamine; induces the formation of esophageal, pharyngeal, and tongue tumors in rats at 200 mg/L in the drinking water or 15 mg/ml via oral gavage; toxic to rats (LD50s = 336 and 225 mg/kg for male and female rats, respectively); reduces survival of hamsters but only induces a low incidence of tumors at 5 mg/week for a total dose of 1.8 mmol
Medchemexpress LLC BUSPIRONE 50.0MG
Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent and can be used for the generalized anxiety disorder research.
Sigma Aldrich Fine Chemicals Biosciences Isopentyl nitrite 96% | 110-46-3 | MFCD00002057 | 100ML
Isopentyl nitrite 96% | Purity: 96% | Mol Wt: 117.15 | 110-46-3 | MFCD00002057 | 100ML
Medchemexpress LLC N-Nitrosomorpholine | 59-89-2 | 99.9% | 1 G
N-Nitrosomorpholine is a photosensitive nitrosamine known for its carcinogenic properties, primarily used in research to construct animal cancer models. It is intended for research applications only and not for patient use.
- Carcinogenic agent for research purposes.
- Used to construct animal cancer models.
- Induces liver disease, including cytoplasmic and nuclear changes.
- Causes toxic damage, single-cell necrosis, and loss of glycogen.
- Promotes giant cell production, bile duct proliferation, and fibrosis.
- Leads to cirrhosis and metastatic liver cancer in animal models.
- Supports the study of molecular and histological changes, including increased serum glutamate-oxaloacetate aminotransferase levels and liver damage.
Medchemexpress LLC N-Nitrosomorpholine | 59-89-2 | 99.98% | 5 G
N-Nitrosomorpholine is a photosensitive nitrosamine that is carcinogenic and can be used to construct animal cancer models. It is for research use only and not sold to patients.
- Photosensitive nitrosamine
- Carcinogenic agent
- Used to construct animal cancer models
- For research use only
- Not sold to patients
Medchemexpress LLC Tripeptide epoxyketone immunoproteasome (LMP-7) inhibitor | 1416709-79-9 | 98.9% | 618.72 g/mol | C37H38N4O5 | 50MG
A selective tripeptide epoxyketone inhibitor of the immunoproteasome LMP7 subunit for biochemical and cellular research. It covalently modifies proteasomal N-terminal threonine active sites and has demonstrated antitumor activity in preclinical studies.
- Selective LMP7 (β5i) immunoproteasome inhibitor.
- Covalently modifies N-terminal threonine active sites.
- Reported IC50 of 22 nM against LMP7.
- Demonstrated inhibition of multiple myeloma cell growth and induction of apoptosis.
- High chemical purity (98.9%).
- Enantiomeric excess 100%.
- Molecular weight 618.72 g/mol and formula C37H38N4O5.
- Supplied in small research pack sizes, e.g., 50 mg.
- For research use only; not for human use.
Enzo Life Sciences Spermine NONOate (25mg). CAS: 136587-13-8
Nitric oxide (NO) donor. A convenient reagent for preparing aqueous solutions of NO. Alternative name: SPER/NO, (Z)-1-N-[3-Aminopropyl]-N-[4-(3-aminopropylammonio)butyl]-amino-diazen-1-ium-1,2-diolate. Purity: ≥97% (NMR). Appearance: White to off-white crystalline solid. Solubility: Soluble in water, methanol or 100% ethanol. Long Term Storage: -80°C.
Medchemexpress LLC (R)-PR-924 | 98.5% | 618.72 | 10 MG
(R)-PR-924 is an isomer of PR-924 used as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor that covalently modifies proteasomal N-terminal threonine active sites. It inhibits growth and triggers apoptosis in multiple myeloma cells, demonstrating antitumor activities.
- Used as an experimental control
- Inhibits growth and triggers apoptosis in multiple myeloma cells
- Covalently modifies proteasomal N-terminal threonine active sites
- Acts as a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor
- Demonstrates antitumor activities
Medchemexpress LLC (R)-PR-924 | 1416709-79-9 | 98.5% | 618.72 | 50 MG
(R)-PR-924 is an isomer of PR-924, which can be used as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor with an IC50 of 22 nM. It covalently modifies proteasomal N-terminal threonine active sites, inhibits growth, and triggers apoptosis in multiple myeloma (MM) cells, also exhibiting antitumor activities.
- Selective immunoproteasome subunit LMP-7 inhibitor.
- Covalently modifies proteasomal N-terminal threonine active sites.
- Inhibits growth in multiple myeloma (MM) cells.
- Triggers apoptosis in multiple myeloma (MM) cells.
- Exhibits antitumor activities.
- Can be used as an experimental control.
eMolecules 24697-70-9 | 2-(4-hydroxybutyl)isoindoline-1,3-dione | MFCD00204335 | 250mg
Pharmablock | 1-methyl-6-oxo-16-dihydropyridine-2-carboxylic acid | 25mg | 788557060 | PBTQ6717 | 59864-31-2 | MFCD17215908 | 153.137 | C7H7NO3
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Cayman Chemical N-NItroso-N-methylnIlIn 50mg
An N-nitrosamine; induces the formation of esophageal, pharyngeal, and tongue tumors in rats at 200 mg/L in the drinking water or 15 mg/ml via oral gavage; toxic to rats (LD50s = 336 and 225 mg/kg for male and female rats, respectively); reduces survival of hamsters but only induces a low incidence of tumors at 5 mg/week for a total dose of 1.8 mmol
Cayman Chemical 5-NItroso-8-quInolInol 100mg
An HDAC inhibitor, antitumor agent that at 10 μM can induce oxidative stress contributing to apoptosis and differentiation in MCF-7 breast cancer cells; inhibits T. gondii tachyzoite propagation in human fibroblasts (EC50 = 80 nM) and inhibits P. falciparum growth in human red blood cells (EC50 = 1.3 μM)
Cayman Chemical N-NItroso FluoxetIn 25mg
A derivative of fluoxetine; genotoxic to S. typhimurium at 0.06-0.12 mg/ml