Organic nitroso compounds
Medchemexpress LLC N-Nitroso-N-methylurea | 684-93-5 | 99.7% | 103.08 | 500 MG
N-Nitroso-N-methylurea is a potent carcinogen, mutagen, and teratogen. It acts as a direct-acting alkylating agent that interacts with DNA, targeting multiple animal organs to induce various cancers and/or degenerative diseases. It is also utilized as a precursor in the synthesis of diazomethane.
- Potent carcinogen, mutagen, and teratogen
- Direct-acting alkylating agent that interacts with DNA
- Targets multiple animal organs to induce various cancers and/or degenerative diseases
- Precursor in the synthesis of diazomethane
- Can be used to construct rat tumor models
- Increases cellular NF-κB activity and I-κBα phosphorylation in human malignant keratinocytes
Medchemexpress LLC N-Nitrosomorpholine-d8 | 1219805-76-1 | 99.7% | 1 MG
N-Nitrosomorpholine-d8 is a deuterium-labeled version of N-Nitrosomorpholine, a light-sensitive nitrosamine and a strong animal carcinogen. This compound is intended for research use only and can be utilized as a tracer or an internal standard for quantitative analysis. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules for quantitation during drug development, with potential impacts on pharmacokinetic and metabolic profiles.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium-labeled compound
- Suitable for research use only
Cayman Chemical N-NItroso SarcosIn-d3 5mg
An internal standard for the quantification of nitroso sarcosine by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences N Nitrosodiethylamine NDEA
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Cayman Chemical N-NItroso-N-methylnIlIn 50mg
An N-nitrosamine; induces the formation of esophageal, pharyngeal, and tongue tumors in rats at 200 mg/L in the drinking water or 15 mg/ml via oral gavage; toxic to rats (LD50s = 336 and 225 mg/kg for male and female rats, respectively); reduces survival of hamsters but only induces a low incidence of tumors at 5 mg/week for a total dose of 1.8 mmol
eMolecules 24697-70-9 | 2-(4-hydroxybutyl)isoindoline-1,3-dione | MFCD00204335 | 250mg
Pharmablock | 1-methyl-6-oxo-16-dihydropyridine-2-carboxylic acid | 25mg | 788557060 | PBTQ6717 | 59864-31-2 | MFCD17215908 | 153.137 | C7H7NO3
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Medchemexpress LLC N-nitroso-N-methyl-4-aminobutyric acid | 61445-55-4 | MFCD00869939 | 99.9% | 146.14 g/mol | C5H10N2O3 | 100 MG
N-Nitroso-N-methyl-4-aminobutyric acid is a tobacco-specific nitrosamine provided as a high-purity research reagent for analytical and toxicological studies. It is intended for laboratory research use only and supplied as a solid; handle with appropriate carcinogen safety precautions.
- Tobacco-specific nitrosamine and carcinogen.
- Used as an analytical standard and in toxicology studies.
- Molecular weight 146.14 g/mol.
- Chemical formula C5H10N2O3.
- CAS number 61445-55-4.
- Reported purity 99.9%.
- Supplied as a 100 mg solid.
- Certificate of analysis available.
Medchemexpress LLC N-nitroso-n-methyl-4-aminobutyric acid | 61445-55-4 | MFCD00869939 | 99.9% | 146.14 | C5H10N2O3 | 50 MG
N-nitroso-n-methyl-4-aminobutyric acid is a tobacco-derived nitrosamine used as a research chemical and analytical reference. It is supplied as a colorless to light yellow liquid with high reported purity and is intended for research use only.
- High purity (HPLC): 99.88%.
- Molecular formula C5H10N2O3.
- Molecular weight 146.14.
- Appearance liquid, colorless to light yellow.
- Available in small milligram packs, including 50 mg.
- CAS number 61445-55-4.
- Tobacco-specific nitrosamine; identified as a carcinogen.
- For research use only; not for sale to patients.
Medchemexpress LLC N-nitroso-3-azabicyclo[3.3.0]octane-d4 | 1346604-35-0 | 95.0% | C7H8D4N2O | 50 MG
N-Nitroso-3-azabicyclo[3.3.0]octane-d4 is the deuterium labeled N-Nitroso-3-azabicyclo[3.3.0]octane. It is used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs
Cayman Chemical N-NItroso-N-methylnIlIn 250mg
An N-nitrosamine; induces the formation of esophageal, pharyngeal, and tongue tumors in rats at 200 mg/L in the drinking water or 15 mg/ml via oral gavage; toxic to rats (LD50s = 336 and 225 mg/kg for male and female rats, respectively); reduces survival of hamsters but only induces a low incidence of tumors at 5 mg/week for a total dose of 1.8 mmol
Cayman Chemical 5-NItroso-8-quInolInol 10mg
An HDAC inhibitor, antitumor agent that at 10 μM can induce oxidative stress contributing to apoptosis and differentiation in MCF-7 breast cancer cells; inhibits T. gondii tachyzoite propagation in human fibroblasts (EC50 = 80 nM) and inhibits P. falciparum growth in human red blood cells (EC50 = 1.3 μM)
Medchemexpress LLC L-tryptophanamide, N-((3-methyl-1H-inden-2-yl)carbonyl)-D-alanyl-N-((1S)-2-((2R)-2-methyl-2-oxiranyl | 1416709-79-9 | 98.9% | 618.72 g·mol⁻¹ | C37H38N4O5 | 10MM 1ML
PR-924 is a selective tripeptide epoxyketone inhibitor of the immunoproteasome subunit LMP-7, intended for research use in biochemical and cellular assays. It is supplied in ready-to-use solutions and in solid quantities to support formulation and dosing studies.
- Selective tripeptide epoxyketone LMP-7 inhibitor.
- Available as 10 mM solution in DMSO and multiple solid sizes.
- High reported purity: 98.9%.
- Molecular weight 618.72 g·mol⁻¹; formula C37H38N4O5.
- Soluble in DMSO; in vivo formulation options described for PEG300/tween/saline and corn oil.
- Storage recommendations provided for powder and in solvent to preserve stability.