Alcohols and polyols
- (1)
- (55)
- (354)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
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- (156)
- (1)
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- (1)
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- (10)
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- (2)
- (1)
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- (1)
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- (6)
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- (30)
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- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (400)
- (6)
- (102)
- (22)
- (50)
- (31)
- (63)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (14)
- (148)
- (116)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
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- (1)
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- (1)
- (1)
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- (1)
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- (30)
- (1)
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- (1)
- (2)
- (1)
- (20)
- (10)
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- (15)
- (1)
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- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
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- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
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- (17)
- (15)
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- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (13)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
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- (1)
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- (1)
- (1)
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- (1)
- (1)
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- (1)
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- (1)
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- (733)
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Filtered Search Results
Medchemexpress LLC Tivozanib hydrochloride hydrate | 682745-41-1 | 99.8% | 509.34 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib. It is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2, and 3, with IC50s of 30, 6.5, and 15 nM, respectively. It demonstrates antitumor efficacy.
- Selective, orally active inhibitor for VEGFR-1, 2, and 3
- Exhibits antitumor efficacy
- Inhibits phosphorylation of VEGFR-1, VEGFR-2, and VEGFR-3 with IC50s of 0.16-0.24 nM in vitro
- Inhibits VEGF-induced proliferation and migration of HUVECs in vitro
- Selectively inhibits VEGF-stimulated phosphorylation of MAPKs in endothelial cells in vitro
- Shows antitumor efficacy against breast, colon, hepatic, lung, ovarian, pancreatic, and prostate cancer in athymic mice models in vivo
- Reversibly suppresses vascular permeability and angiogenesis in Calu-6 tumor bearing rats in vivo
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Research Products International Corp Ninhydrin Reagent 1 KG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Ninhydrin Reagent, 1 Kilogram
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eMolecules 29671-92-9 | Chloroformamidine hydrochloride | Chem-Impex | MFCD00035527 | 114.960 | CH4Cl2N2 | 99.000 | Cl.NC(Cl)=N | 5g | 386903866
Chloroformamidine hydrochloride | Chem-Impex | 29671-92-9 | MFCD00035527 | 114.960 | CH4Cl2N2 | 99.000 | Cl.NC(Cl)=N | 5g | 386903866
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 13071-11-9 | 2R-(+)-Propanolol hydrochloride | Chem-Impex | MFCD00012558 | 295.810 | C16H22ClNO2 | 95.000 | Cl.CC(C)NCC(O)COc1cccc2ccccc12 | 1g | 112446705
2R-(+)-Propanolol hydrochloride | Chem-Impex | 13071-11-9 | MFCD00012558 | 295.810 | C16H22ClNO2 | 95.000 | Cl.CC(C)NCC(O)COc1cccc2ccccc12 | 1g | 112446705
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Medchemexpress LLC Taltobulin hydrochloride | 228266-40-8 | 99.3% | 510.11 g/mol | C27H44ClN3O4 | 10 MG
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Taltobulin hydrochloride is the hydrochloride salt of taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin that functions as a potent tubulin (microtubule) inhibitor for preclinical cancer research and ADC payload development.
- Potent tubulin inhibitor that disrupts microtubule organization.
- Exhibits low-nanomolar in vitro activity (median IC50 ~1.7 nM).
- Demonstrated in vivo activity in mouse xenograft models (examples: 1.6 mg/kg i.v., 3 mg/kg p.o.).
- Supplied as a white to off-white solid for research use.
- Storage: solid at 4°C, sealed and protected from moisture; solutions stored at -80°C or -20°C for limited durations.
- High reported purity (~99.3%) suitable for biological studies.
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Medchemexpress LLC Defactinib hydrochloride | 1073160-26-5 | 99.4% | 50 MG
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Defactinib hydrochloride is the hydrochloride salt of defactinib (VS-6063; PF-04554878), a small-molecule focal adhesion kinase (FAK) inhibitor used in research to study FAK signaling, tumor cell motility, and antineoplastic and antiangiogenic mechanisms.
- Inhibits FAK phosphorylation at Tyr397 in a time- and dose-dependent manner.
- Hydrochloride salt form, off-white powder suitable for research use.
- Molecular formula C20H22ClF3N8O3S; molecular weight 546.95 g/mol.
- Reported purity 99.35% with available certificate of analysis.
- Available in multiple pack sizes, including 50 mg.
- Supporting documents available: data sheet, COA, and SDS.
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Medchemexpress LLC Proadifen (hydrochloride) | 62-68-0 | 99.95% | 1 ML
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Proadifen hydrochloride, also known as SKF-525A, is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. It reduces monoamine oxidase A activity and N,N-dimethyltryptamine metabolism. This compound is promising for research related to metabolism-related diseases, ovarian carcinoma, inflammation, and dopamine neuron-related diseases.
- Reduces monoamine oxidase A activity
- Reduces N,N-dimethyltryptamine metabolism in liver microsomes
- Inhibits N-demethylation and Acridone formation
- Augments lipopolysaccharide-induced fever
- Exacerbates prostaglandin E2 levels in rats
- Promising for research of metabolism-related diseases
- Promising for research of ovarian carcinoma
- Promising for research of inflammation
- Promising for research of dopamine neuron-related diseases
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Medchemexpress LLC Imidapril (hydrochloride) | 89396-94-1 | 99.9% | 50 MG
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Imidapril hydrochloride (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. It suppresses the conversion of angiotensin I to angiotensin II, reducing total peripheral resistance and systemic blood pressure. It is used for research related to hypertension, type 1 diabetic nephropathy, and chronic heart failure.
- Orally active ACE inhibitor
- MMP-9 inhibitor
- Suppresses angiotensin I to angiotensin II conversion
- Reduces total peripheral resistance
- Reduces systemic blood pressure
- Used for hypertension research
- Used for type 1 diabetic nephropathy research
- Used for chronic heart failure research
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Medchemexpress LLC Leonurine hydrochloride | 24735-18-0 | 347.79 | 100 MG
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Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia, exhibiting anti-oxidative and anti-inflammatory properties. This compound is intended for research use only, playing a role in various biological activities in vitro and in vivo.
- Causes diminution in lipid accumulation and cellular cholesterol content.
- Increases apoA-I- or HDL-mediated cholesterol efflux.
- Significantly increases the expressions of ABCA1 and ABCG1.
- Shows protective effects on cell viability of HepG2 and HL-7702 cells.
- Improves cellular lipid accumulation via activating AMPK/SREBP1 pathway.
- Inhibits the expression of iNOS, COX-2, PGE2, NO, TNF-α, and IL-6.
- Suppresses ECM degradation in human OA chondrocytes.
- Blocks IL-1β-induced PI3K and Akt phosphorylation.
- Ameliorates osteoarthritis development in mouse DMM model.
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Medchemexpress LLC Simufilam hydrochloride (PTI-125 hydrochloride) | 2480226-07-9 | 99.9% | 295.81 | 25 MG
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Simufilam hydrochloride (PTI-125 hydrochloride) is an orally active FLNA modulator. It restores NMDAR signaling and Arc expression. It inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Aβ42-induced neuroinflammation, and tau protein hyperphosphorylation. This product can be used for research related to Alzheimer's disease.
- Reduces FLNA-α7nAChR/TLR4 associations and dissociates Aβ42-α7nAChR complexes.
- Restores α7nAChR/NMDAR/IR function and NMDAR signaling and arc expression in human AD brain slices.
- Decreases tau phosphorylation, Aβ42 aggregates, and inflammatory cytokines in mouse models.
- Improves NMDAR/IR function, synaptic plasticity, spatial/working memory, and nesting behavior in 3xTg AD mice.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000381209 PDK4-IN-1 HYDROCHLO 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000381279 SB-505124 HYDROCHLO 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378610 AP-III-A4 HYDROCHLO 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380507 ENPATORAN HYDROCHLO 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380977 BELOTECAN HYDROCHLO 50MG
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