Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,351 – 4,365 of 5,342 results

4,351

eMolecules Ambeed / Dibenzo[bd]thiophene-2-carbaldehyde / 1g / 600827214 / A108182 / / 22099-23-6 / MFCD02251670 / 212.270 / C13H8OS

Ambeed / Dibenzo[bd]thiophene-2-carbaldehyde / 1g / 600827214 / A108182 / / 22099-23-6 / MFCD02251670 / 212.270 / C13H8OS

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4,352

Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 100 MG

Dopexamine hydrochloride is a β2 adrenergic receptor agonist, intended for research use only. This dopamine analogue exhibits agonist activity at β2 and dopaminergic receptors, making it suitable for studies on inflammatory response and organ protection.

Attenuates systemic inflammatory response
Reduces tissue leukocyte infiltration
Protects against organ injury
Reduces systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress

Pricing & Availability

4,353

Medchemexpress LLC Eglumegad hydrochloride | 176199-48-7 | 99.63% | 221.64 | 5 MG

Eglumegad hydrochloride is a highly potent and selective group II (mGlu2/3) receptor agonist. It protects neurons from NMDA toxicity and has anxiolytic- and antipsychotic-like effects.

Highly potent and selective group II (mGlu2/3) receptor agonist.
Protects neurons from NMDA toxicity.
Has anxiolytic-like effects.
Has antipsychotic-like effects.

Pricing & Availability

4,354

Medchemexpress LLC Embramine hydrochloride | 13977-28-1 | 384.74 | 25 MG

Embramine hydrochloride is a monoethanolamine that functions as an antihistamine and anticholinergic. It is intended for research use only.

Functions as an antihistamine
Functions as an anticholinergic
Targets Histamine Receptor
Involved in GPCR/G protein, immunology/inflammation, and neuronal signaling pathways

Pricing & Availability

4,355

Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 1 ML

Ansofaxine hydrochloride (LY03005) is a triple reuptake inhibitor that targets serotonin, dopamine, and norepinephrine. It is intended for research use only.

Inhibits serotonin reuptake (IC50: 723 nM)
Inhibits dopamine reuptake (IC50: 491 nM)
Inhibits norepinephrine reuptake (IC50: 763 nM)
Purity of 99.44%
Molecular weight of 417.97

Pricing & Availability

4,356

Medchemexpress LLC SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 1 ML

SCH-23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. It is also a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM, and binds with high affinity to 5-HT2 and 5-HT1C receptors. It inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM. For research use only.

Potent and selective dopamine D1-like receptor antagonist.
Potent and high efficacy human 5-HT2C receptor agonist.
Binds with high affinity to 5-HT2 and 5-HT1C receptors.
Inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels.
Used in studies of neurological disorders like psychosis and Parkinson's disease.
Used in topographical determination of brain D1 receptors.

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4,357

Medchemexpress LLC VU0453379 (hydrochloride) | 99.0% | 471.03 | 10 MG

VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM.

Highly selective
Central nervous system (CNS) penetrant
Positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R)

Pricing & Availability

4,358

Medchemexpress LLC Ru-ski 43 hydrochloride | 1782573-67-4 | 98.8% | 423.01 | 50 MG

RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. It also exhibits anti-cancer activity.

Potent and selective Hhat inhibitor (IC50 = 850 nM).
Reduces Gli-1 activation via Smoothened-independent non-canonical signaling.
Decreases Akt and mTOR pathway activity.
Possesses anti-cancer activity.

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4,359

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g/mol | C24H34ClN5O4S | 50MG

Yonkenafil hydrochloride is a research-grade phosphodiesterase 5 (PDE5) inhibitor supplied as the hydrochloride salt for laboratory pharmacology studies. It has demonstrated neuroprotective and cognitive effects in preclinical models and is suitable for both in vitro assays and in vivo formulations. This material is intended for research use only and should be handled and stored to minimize moisture exposure.

Purity 99.4%.
Molecular weight 524.08 g/mol.
Chemical formula C24H34ClN5O4S.
Soluble in DMSO at 100 mg/mL with sonication.
Formulatable for in vivo dosing at ≥2.5 mg/mL in recommended vehicles.
Store sealed and protected from moisture and light; freeze solutions for longer-term storage.

Pricing & Availability

4,360

Medchemexpress LLC GB111-NH2 hydrochloride | 99.26% | 610.14 | 1 ML

GB111-NH2 hydrochloride is a cysteine cathepsin inhibitor, which can be used for cancer study. It is for research use only and not sold to patients.

Purity: 99.26%
Molecular weight: 610.14
Formula: C33H40ClN3O6
Appearance: Solid
Color: White to off-white
Storage: -20°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light).
Solubility (in vitro): DMSO: 125 mg/mL (204.87 mM; needs ultrasonic; hygroscopic DMSO has a significant impact on solubility, use newly opened DMSO).
Related classifications: Metabolic enzyme/protease, cathepsin.

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4,361

Medchemexpress LLC Iptacopan (hydrochloride) | 1646321-63-2 | 99.83% | 25 MG

Iptacopan (LNP023) hydrochloride is an effective, orally-active, and highly selective factor B inhibitor. With an IC50 of 10 nM and a KD of 7.9 nM, it exerts a proximal effect in the complement cascade reaction, preventing the destruction of red blood cells in PNH and damage to renal cells in IgAN and C3G. It is used for studying complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G).

Highly selective factor B inhibitor.
Orally active.
Potent inhibition of alternative complement pathway (AP)-induced membrane attack complex (MAC) formation.
Excellent selectivity over other proteases.
Prevents destruction of red blood cells in PNH.
Prevents damage to renal cells in IgAN and C3G.
Used for studying complement-mediated diseases.

Pricing & Availability

4,362

Medchemexpress LLC Voreloxin Hydrochloride | 175519-16-1 | 99.6% | 437.90 | 100 MG

Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.

A first-in-class topoisomerase II poison and inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.
Inhibits topoisomerase II activity and induces site-selective DNA DSB.
Induces G2 arrest partially through topoisomerase II.
Cytotoxic activity requires DNA intercalation.
Demonstrates potent cytotoxic activity in AML cell lines.
Causes accumulation of cells in the S and G2 phases of the cell cycle and acts on topoisomerase II.

Pricing & Availability

4,363

Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | 98.9% | 273.75 g/mol | C13H20ClNO3 | 25MG

Viloxazine hydrochloride is the hydrochloride salt of viloxazine, a selective norepinephrine reuptake inhibitor supplied as a research-grade solid reference compound. It is intended for biochemical and pharmacological studies and includes analytical and storage guidance. For research use only; not for human or veterinary use.

High purity: 98.9% (reported by supplier)
Molecular formula: C13H20ClNO3
Molecular weight: 273.75 g/mol
Form: solid powder suitable for formulation or assay
Storage: store sealed, away from moisture; recommended 4°C; in solvent, -80°C (6 months) or -20°C (1 month)
Available in small quantities suitable for research (for example, 25 mg)

Pricing & Availability

4,364

Medchemexpress LLC mAChR-IN-1 hydrochloride | 119391-73-0 | 99.6% | 524.82 g/mol | C23H26ClIN2O2 | 100MG

mAChR-IN-1 hydrochloride is a research-grade muscarinic acetylcholine receptor antagonist provided for laboratory use. It exhibits potent inhibitory activity against mAChR with a reported IC50 of 17 nM. The compound is supplied as a hydrochloride salt, with formula C23H26ClIN2O2 and molecular weight 524.82 g/mol.

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4,365

Medchemexpress LLC Taltobulin hydrochloride | 228266-40-8 | 99.3% | 510.11 Da | C27H44ClN3O4 | 100 MG

Taltobulin hydrochloride is a synthetic analogue of the tripeptide hemiasterlin and a potent antimicrotubule agent. It inhibits tubulin polymerization, disrupts microtubule organization, and induces mitotic arrest, and is supplied as a solid research reagent for in vitro and in vivo studies.

Potent tubulin inhibitor with low-nanomolar activity in tumor cell lines.
High purity suitable for research applications.
Supplied as a solid powder for solution preparation in DMSO or aqueous buffers.
Recommended solvent and formulation guidance provided for in vitro and in vivo use.
Store sealed at 4°C; solutions stable at -80°C for long-term storage.

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Alcohols and polyols

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Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Eglumegad hydrochloride | 176199-48-7 | 99.63% | 221.64 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Embramine hydrochloride | 13977-28-1 | 384.74 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VU0453379 (hydrochloride) | 99.0% | 471.03 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ru-ski 43 hydrochloride | 1782573-67-4 | 98.8% | 423.01 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g/mol | C24H34ClN5O4S | 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GB111-NH2 hydrochloride | 99.26% | 610.14 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Iptacopan (hydrochloride) | 1646321-63-2 | 99.83% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Voreloxin Hydrochloride | 175519-16-1 | 99.6% | 437.90 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | 98.9% | 273.75 g/mol | C13H20ClNO3 | 25MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC mAChR-IN-1 hydrochloride | 119391-73-0 | 99.6% | 524.82 g/mol | C23H26ClIN2O2 | 100MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Taltobulin hydrochloride | 228266-40-8 | 99.3% | 510.11 Da | C27H44ClN3O4 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More