Alcohols and polyols
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- (1)
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- (1)
- (462)
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- (11)
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- (1)
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- (145)
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- (1)
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- (2)
- (2)
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- (1)
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- (7)
- (3)
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- (1)
- (36)
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- (2)
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- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
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- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
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- (1)
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Filtered Search Results
Medchemexpress LLC Betaxolol hydrochloride | 63659-19-8 | 98.12% | 100 MG
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Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. It is a cardioselective beta-adrenergic receptor blocking agent. It has been shown to diminish anxiety-like behavior during early withdrawal from chronic cocaine administration in rats, and it produces less systemic beta 2- and possibly beta 1-adrenergic receptor blockade than either timolol or levobunolol, potentially making it safer for patients with reactive airway disease.
- Selective beta1 adrenergic receptor blocker
- Used in research for hypertension and glaucoma
- Cardioselective beta-adrenergic receptor blocking agent
- Diminishes anxiety-like behavior during withdrawal from chronic cocaine administration in rats
- Produces less systemic beta 2- and possibly beta 1-adrenergic receptor blockade
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Amprolium hydrochloride | 137-88-2 | 98.79% | 250 MG
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Amprolium hydrochloride is an anti-parasitic drug that is taken orally and acts as an antagonist to thiamine in intestinal absorption. It is for research use only and not sold to patients.
- Acts as an antagonist to thiamine in intestinal absorption
- Targets Coccidia
- Suitable for in vivo and in vitro applications
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Alfuzosin hydrochloride | 81403-68-1 | 99.7% | 50 MG
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Alfuzosin hydrochloride is an orally active, selective and competitive α1-adrenoceptor antagonist. It relaxes the muscles of the prostate and bladder neck, aiding in urination. This compound can be used in the study of benign prostatic hyperplasia (BPH).
- Orally active
- Selective and competitive α1-adrenoceptor antagonist
- Relaxes the muscles of the prostate and bladder neck
- Aids in urination
- Can be used in the study of benign prostatic hyperplasia (BPH)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Nebivolol hydrochloride | 152520-56-4 | MFCD07357273 | 99.9% | 50 MG
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Nebivolol hydrochloride is an orally active beta receptor blocker with high beta(1)-receptor affinity. It possesses direct vasodilator properties and adrenergic blocking characteristics. This compound is used for the research of various diseases such as hypertension, coronary artery disease, congestive heart failure, and ischemic heart disease.
- Orally active beta receptor blocker
- High beta(1)-receptor affinity
- Direct vasodilator properties
- Adrenergic blocking characteristics
- Improves endothelial dysfunction
- Stimulates endothelial nitric oxide synthase activity
- Antioxidative properties
- Inhibits haCSMC and haEC proliferation
- Induces moderate apoptosis
- Increases NO formation and decreases endothelin-1 secretion
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Medchemexpress LLC Articaine hydrochloride | 23964-57-0 | 99.4% | 1 ML
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Articaine hydrochloride is a selective inhibitor of voltage-gated sodium channels, demonstrating local anesthetic activity by blocking nerve impulse conduction. It also exhibits anti-inflammatory functions by inhibiting NF-κB activation and NLRP3 inflammasome pathways. It is used in the study of dental local anesthesia and inflammatory-related diseases.
- Inhibits voltage-gated sodium channels
- Exhibits local anesthetic activity
- Inhibits NF-κB activation and NLRP3 inflammasome pathways
- Reduces inflammatory factors like TNF-α, IL-6, and IL-1β
- Ameliorates LPS-induced acute kidney injury in animal models
- Can enhance anesthetic effect in zebrafish model
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Medchemexpress LLC Epz020411 (hydrochloride) | 2070015-25-5 | 98.15% | 10MM 1ML
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EPZ020411 hydrochloride is a selective inhibitor of PRMT6 with an IC50 of 10 nM. It demonstrates more than 10-fold selectivity for PRMT6 over PRMT1 and PRMT8 and can be used for cancer research.
- Selective inhibitor of PRMT6 (IC50 of 0.01 μM).
- Exhibits over 10-fold selectivity for PRMT6 compared to PRMT1 and PRMT8.
- Decreases H3R2 methylation in A375 cells.
- Reduces neomycin- and cisplatin-induced cell apoptosis and increases hair cell survival.
- Attenuates neomycin- and cisplatin-induced hearing loss in mice.
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Medchemexpress LLC BMY 14802 hydrochloride | 105565-55-7 | MFCD04039786 | 98.0% | 384.85 | C18H23ClF2N4O | 5 MG
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BMY-14802 hydrochloride is the hydrochloride salt of a selective and orally active sigma receptor antagonist that also exhibits 5-HT1A agonist and α1-adrenergic activity. It is used in preclinical research exploring antipsychotic effects and movement disorders, and is supplied for research use only.
- Selective sigma receptor antagonist with reported IC50 = 112 nM.
- Also displays 5-HT1A agonist activity and α1-adrenergic effects.
- Supplied for research use only; not for human or veterinary use.
- High purity by HPLC (≈98.0%).
- Available as solid and as a 10 mM solution in DMSO.
- Molecular weight 384.85; formula C18H23ClF2N4O.
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Medchemexpress LLC Trazodone (hydrochloride) | 25332-39-2 | 99.6% | 100 MG
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Trazodone (hydrochloride) is a triazolopyridine derivative that acts as a serotonin receptor antagonist and reuptake inhibitor (SARI). It exhibits antidepressant and anti-insomnia activity, alongside antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects. This product is intended for use as a laboratory chemical and for substance manufacturing, and is stable under recommended storage conditions.
- Triazolopyridine derivative
- Serotonin receptor antagonist and reuptake inhibitor (SARI)
- Demonstrates antidepressant and anti-insomnia activity
- Exhibits antagonistic properties against α1- and α2-adrenergic and histamine H1 receptors
- Minimal anticholinergic effects
- Stable under recommended storage conditions
- For research use only
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Medchemexpress LLC Trazodone (hydrochloride) | 25332-39-2 | 99.6% | 50 MG
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This product is a triazolopyridine derivative, classified as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates antidepressant and anti-insomnia activities by antagonizing α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects. It is intended for research use only.
- Classified as a serotonin receptor antagonist and reuptake inhibitor (SARI)
- Exhibits antidepressant and anti-insomnia activity
- Antagonizes α1- and α2-adrenergic receptors
- Antagonizes histamine H1 receptors
- Minimal anticholinergic effects
- Purity of 99.60%
- Molecular formula: C19H23Cl2N5O
- Appears as a white to off-white solid
- Soluble in DMSO and water
- Binds to 5-HT1A receptor with high affinity
- Inhibits key signaling pathways for neuroinflammatory markers
- Increases BDNF and CREB expression
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Medchemexpress LLC Lidocaine hydrochloride hydrate | 6108-05-0 | 99.8% | 50 MG
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Lidocaine hydrochloride hydrate is a sodium channel blocker that inhibits sodium channels with complex voltage and use dependence. It decreases the growth, migration, and invasion of gastric carcinoma cells by up-regulating miR-145 expression and inactivating the MEK/ERK and NF-κB signaling pathways. This amide derivative shows potential for research into ventricular arrhythmia.
- Inhibits sodium channels
- Decreases growth, migration, and invasion of gastric carcinoma cells
- Upregulates miR-145 expression
- Inactivates MEK/ERK and NF-κB signaling pathways
- Decreases cell proliferation and viability in MKN45 cells
- Increases apoptotic cell rate in MKN45 cells
- Down-regulates Cyclin D1 and up-regulates p21 expression in MKN45 cells
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Medchemexpress LLC Moexipril hydrochloride | 82586-52-5 | 98.4% | 50 MG
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Moexipril hydrochloride is an orally active inhibitor of angiotensin-converting enzyme (ACE) that becomes effective by being hydrolyzed to moexiprila (hydrochloride). It exhibits antihypertensive and neuroprotective effects and is for research use only.
- Orally active ACE inhibitor
- Exhibits antihypertensive effects
- Exhibits neuroprotective effects
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Medchemexpress LLC Dyclonine hydrochloride | 536-43-6 | 99.3% | 1 ML
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Dyclonine hydrochloride, also known as Dyclocaine hydrochloride, is an orally effective covalent inhibitor of Aldehyde Dehydrogenase (ALDH) that can cross the blood-brain barrier. It demonstrates sensitizing activities for targeted cancer cells and exhibits antibacterial properties. Additionally, Dyclonine hydrochloride functions as a local anesthetic, capable of suppressing or relieving pain by blocking the transmission of nerve impulses and inhibiting the sensation of touch and pain.
- Orally effective ALDH covalent inhibitor
- Crosses the blood-brain barrier
- IC50 of 35 μM for ALDH2 and 76 μM for ALDH3A1
- Sensitizes targeted cancer cells
- Possesses antibacterial activity
- Acts as a local anesthetic to suppress and relieve pain
- Blocks the transmission of nerve impulses
- Inhibits the sensation of touch and pain
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Medchemexpress LLC Terazosin hydrochloride dihydrate | 70024-40-7 | 99.5% | 1 ML
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Terazosin hydrochloride dihydrate is a quinazoline derivative and a competitive, orally active α1-adrenoceptor antagonist. It functions by relaxing blood vessels and aiding in the opening of the bladder. This compound has potential applications in the treatment of benign prostatic hyperplasia (BPH) and high blood pressure. This product is for research use only.
- Competitive α1-adrenoceptor antagonist
- Relaxes blood vessels
- Aids in opening the bladder
- Potential for treating benign prostatic hyperplasia (BPH)
- Potential for treating high blood pressure
- Does not differentiate cloned α1-adrenoceptor subtypes
- Can promote stone discharge in the treatment of ureteral stones
- Reportedly safe and effective for distal ureteral stones, especially those >5 mm
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Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 g·mol⁻¹ | C21H26ClN | 500 MG
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Melitracen hydrochloride is an orally active tricyclic antidepressant research compound that inhibits norepinephrine and serotonin reuptake. Supplied as the hydrochloride salt, it is intended for in vitro and preclinical investigation of monoaminergic activity.
- Inhibits norepinephrine and serotonin reuptake, increasing monoamine availability.
- Provided as the hydrochloride salt for improved stability and solubility.
- High reported purity (≈99.8%) suitable for research applications.
- Molecular formula C21H26ClN, molecular weight 327.89 g·mol⁻¹.
- Soluble in DMSO and water at high concentrations with sonication.
- Recommended sealed storage away from moisture; short-term storage in solution at low temperatures.
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Medchemexpress LLC Molindone hydrochloride | 15622-65-8 | 99.8% | 5 MG
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Molindone hydrochloride (EN-1733A) is an orally active, brain-penetrant dopamine D2/D5 receptor antagonist. It demonstrates antipsychotic and antidepressant-like activities, suppresses spontaneous locomotion, and antagonizes apomorphine-induced emesis. This compound is suitable for research related to neurological diseases.
- Orally active and brain-penetrant D2/D5 receptor antagonist
- Exhibits antipsychotic and antidepressant-like activities
- Suppresses spontaneous locomotion
- Antagonizes apomorphine-induced emesis
- Targeted to D2 and D5 receptors
- Soluble in water (100 mg/mL; ultrasonic needed)
- Soluble in DMSO (17.5 mg/mL; ultrasonic and warming needed)
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