Alcohols and polyols
trans-4-(Hydroxymethyl)cyclohexanecarboxylic Acid 98.0+%, TCI America™
CAS: 66185-74-8 Molecular Formula: C8H14O3 Molecular Weight (g/mol): 158.20 MDL Number: MFCD10566907,MFCD01734677,MFCD10566906 InChI Key: VQMIUUBKKPIDBN-UHFFFAOYSA-N PubChem CID: 202819 IUPAC Name: 4-(hydroxymethyl)cyclohexane-1-carboxylic acid SMILES: OCC1CCC(CC1)C(O)=O
Medchemexpress LLC Alectinib (Hydrochloride) | 1256589-74-8 | 99.9% | 100 MG
Alectinib Hydrochloride is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner). It effectively inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively, and demonstrates effective central nervous system (CNS) penetration.
- Potent, selective, and orally available ALK inhibitor
- Effective central nervous system (CNS) penetration
- Molecular formula: C30H35ClN4O2
- Molecular weight: 519.08
- Appearance: White to off-white solid
- Recommended storage at 4°C, sealed and away from moisture
Medchemexpress LLC Alectinib Hydrochloride | 1256589-74-8 | 99.9% | 200 MG
Alectinib (CH5424802; RO5424802; RG7853) Hydrochloride is a potent, selective, and orally available ALK inhibitor. It has an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner). It also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.
- Potent and selective ALK inhibitor
- Orally available
- Effective central nervous system (CNS) penetration
- Inhibits ALK F1174L and ALK R1275Q
Medchemexpress LLC Alectinib hydrochloride | 1256589-74-8 | 99.9% | 25 MG
Alectinib hydrochloride is a potent, selective, and orally available ALK inhibitor. It demonstrates effective central nervous system (CNS) penetration.
- Potent and selective ALK inhibitor
- Orally available
- Inhibits ALK F1174L and ALK R1275Q
- Effective central nervous system (CNS) penetration
- Reduces cell activity in a dose-dependent manner
- Leads to dose-dependent tumor growth inhibition and regression
Medchemexpress LLC Alectinib hydrochloride | 1256589-74-8 | MFCD27987893 | 99.9% | C30H35ClN4O2 | 10MG
Alectinib hydrochloride is the hydrochloride salt of alectinib, a potent and selective anaplastic lymphoma kinase (ALK) inhibitor. It is supplied as a research-grade analytical standard for biochemical and cell-based assays and includes documentation to support analytical verification. Intended for research use only.
- High purity (99.9%) for analytical applications.
- Verified identity with CAS 1256589-74-8.
- Available in multiple small pack sizes for method development.
- Soluble in common organic solvents for assay preparation.
- Supplied with COA and datasheet for traceability.
eMolecules (+)-1-Phenyl-1-propanol | 1565-74-8 | MFCD00064279 | 1g
Oakwood Chemical | (+)-1-Phenyl-1-propanol | 1g | 537710266 | 103637 | | 1565-74-8 | MFCD00064279 | 136.194 | C9H12O
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Medchemexpress LLC 3-epi-Vitamin D3 | 57651-82-8 | C27H44O | 5 MG
A Vitamin D3 analogue, this compound acts as a Hedgehog pathway inhibitor with an IC50 of 39.2 μM in U87MG cells. It significantly upregulates Cyp24A1 in U87MG, HT-29, and C3H10T1/2 cells at concentrations of 5 or 10 μM. It exhibits antiproliferative activity against human U87MG cells after 72 hours, as measured by MTS assay.
- Exhibits specific inhibitory activity against the Hedgehog pathway.
- Demonstrates antiproliferative effects in certain human cell lines.
- Induces upregulation of a key metabolic enzyme in multiple cell types.
Medchemexpress LLC 3-epi-Vitamin D3 (Epicholecalciferol) | 57651-82-8 | C27H44O | 50 MG
3-epi-Vitamin D3 (Epicholecalciferol) is an analogue of Vitamin D3. It functions as a Hedgehog pathway inhibitor with an IC50 of 39.2 μM in U87MG cells. This product is intended for research use only and is not for patient use.
- Acts as a Hedgehog pathway inhibitor
- Exhibits antiproliferative activity against U87MG cells
- Significantly upregulates Cyp24A1 in U87MG, HT-29 and C3H10T1/2 cells
Medchemexpress LLC 3-epi-Vitamin D3 (Epicholecalciferol) | 57651-82-8 | C27H44O | 1 MG
3-epi-Vitamin D3 (Epicholecalciferol) is a Vitamin D3 analogue that functions as a Hedgehog pathway inhibitor. It demonstrates an IC50 of 39.2 μM when measured in U87MG cells, and notably upregulates Cyp24A1 in U87MG, HT-29, and C3H10T1/2 cells at concentrations of 5 or 10 μM. This compound is presented as a white to light yellow solid with a purity of 94.11% by HPLC, and is intended for research use only.
- Functions as a Vitamin D3 analogue
- Acts as a Hedgehog pathway inhibitor
- Exhibits an IC50 of 39.2 μM in U87MG cells
- Significantly upregulates Cyp24A1 in U87MG, HT-29, and C3H10T1/2 cells
- Appears as a white to light yellow solid
- Purity of 94.11% (HPLC)
- For research use only
eMolecules 1-Cyclohexyl-2-buten-1-ol | 18736-82-8 | MFCD00060819 | 1g
Oakwood Chemical | 1-Cyclohexyl-2-buten-1-ol | 1g | 537710474 | 103866 | | 18736-82-8 | MFCD00060819 | 154.253 | C10H18O
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Medchemexpress LLC HY-N2250 5mg Medchemexpress, Hosenkoside B CAS:156764-82-8 Purity:>98%
Medchemexpress, HY-N2250 5mg Hosenkoside B CAS:156764-82-8 Hosenkoside B is a baccharane glycoside isolated from the seeds of impatiens balsamina. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules Medchem Express / CINPA1 / 5mg / 506403688 / HY-110249 / / 102636-74-8 / MFCD00288296 / 395.503 / C23H29N3O3
Medchem Express / CINPA1 / 5mg / 506403688 / HY-110249 / / 102636-74-8 / MFCD00288296 / 395.503 / C23H29N3O3
eMolecules Ambeed Pyrrolidin-3-ol hydrochloride 5g 525036786 A131822 86070-82-8 MFCD03001754 123.580 C4H10ClNO
Ambeed Pyrrolidin-3-ol hydrochloride 5g 525036786 A131822 86070-82-8 MFCD03001754 123.580 C4H10ClNO
eMolecules Ambeed / (R)-()-1-Phenyl-1-propanol / 100mg / 592282770 / A309310 / / 1565-74-8 / MFCD00064279 / 136.194 / C9H12O
Ambeed / (R)-()-1-Phenyl-1-propanol / 100mg / 592282770 / A309310 / / 1565-74-8 / MFCD00064279 / 136.194 / C9H12O
Medchemexpress LLC 3-epi-vitamin D3 (epicholecalciferol) | 57651-82-8 | MFCD28963703 | 94.1% | 384.64 g·mol⁻1 | C27H44O | 10 MG
3-epi-Vitamin D3 (Epicholecalciferol) is a vitamin D3 analogue used in research to modulate the Hedgehog signaling pathway. It exhibits antiproliferative activity in human U87MG cells (IC50 = 39.2 μM, MTS assay, 72 h) and is provided as a purified small-molecule powder for in vitro studies.
- Molecular formula C27H44O.
- Molecular weight 384.64 g·mol⁻1.
- CAS number 57651-82-8.
- Purity 94.1%.
- Bioactivity Hedgehog pathway inhibition; IC50 = 39.2 μM in U87MG cells (MTS assay, 72 h).
- Supplied in milligram pack sizes suitable for cell-based assays.