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Filtered Search Results
Medchemexpress LLC EGTA-AM (EGTA Acetoxymethyl ester) | 99590-86-0 | 99.8% | 1 MG
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EGTA-AM is a membrane permeable form of EGTA, which can be passively loaded into cells to generate intracellular EGTA. It is also a Ca2+ chelator with slow chelating dynamics. For research use only.
- Membrane permeable, allowing passive loading into cells.
- Generates intracellular EGTA.
- Ca2+ chelator with slow chelating dynamics.
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Medchemexpress LLC Nonaethylene glycol 10g | 3386-18-3 | 414.49 g/mol | C18H38O10 | 10 G
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Nonaethylene glycol is a polyethylene glycol (PEG)-based PROTAC linker used as a hydrophilic, flexible spacer in the synthesis and optimization of bifunctional degrader molecules. The nine-unit ethylene glycol chain increases solubility and provides conformational freedom for connecting ligands or warheads.
- PEG-based linker with nine ethylene glycol units for flexibility.
- Enhances aqueous solubility of conjugates.
- Suitable for linker optimization in PROTAC synthesis.
- Available as a solid for routine synthetic workflows.
- Stable when stored under recommended conditions.
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Medchemexpress LLC Octaethylene glycol | 5117-19-1 | MFCD00698694 | 100.0% | 370.44 g/mol | C16H34O9 | 5 G
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Octaethylene glycol is a polyethylene glycol (PEG) linker composed of eight ethylene glycol units. It is a hydrophilic spacer used in chemical synthesis, commonly as a linker for proteolysis targeting chimeras (PROTACs) and other bioconjugation applications. The substance is a diol with terminal hydroxyl groups and is soluble in water and polar organic solvents.
- Cas number 5117-19-1.
- Molecular formula C16H34O9.
- Molecular weight 370.44 g/mol.
- High purity suitable for research use.
- Functional groups: terminal hydroxyls for conjugation.
- Uses: peg-based linker for PROTAC synthesis and bioconjugation.
- Available in small lab-scale quantities (5 G pack).
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eMolecules 1146169-44-9 | 4-[(2-methoxyethoxy)methyl]phenylboronic acid | Combi-Blocks | MFCD14687278 | 210.040 | C10H15BO4 | 98.000 | COCCOCc1ccc(cc1)B(O)O | 1g | 117529684
4-[(2-methoxyethoxy)methyl]phenylboronic acid | Combi-Blocks | 1146169-44-9 | MFCD14687278 | 210.040 | C10H15BO4 | 98.000 | COCCOCc1ccc(cc1)B(O)O | 1g | 117529684
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Medchemexpress LLC Hexaethylene glycol | 2615-15-8 | 99.5% | C12H26O7 | 10 G
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Hexaethylene glycol is a PEG-based PROTAC linker that plays a crucial role in the synthesis of PROTACs. These molecules are designed with two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other binding to a target protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of specific target proteins.
- Acts as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTAC molecules
- Facilitates the degradation of target proteins via the ubiquitin-proteasome system
- For research use only
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Sigma Aldrich Fine Chemicals Biosciences 1,2-Dimethoxyethane | 110-71-4 | MFCD00008502 | 100ML
1,2-Dimethoxyethane | 110-71-4 | MFCD00008502 | 100ML ** For R&D use only. Not for drug, household, or other uses. CAS RN 110-71-4 is under an EPA TSCA Significant New Use Rule (40 CFR 721.10229). Website-reference: https://www.govinfo.gov/content/pkg/CFR-2018-title40-vol33/pdf/CFR-2018-title40-vol33-sec721-10229.pdf
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eMolecules 2089325-76-6 | 4-FLUOROTETRAHYDROFURAN-3-AMINE HYDROCHLORIDE | AstaTech141.570 | C4H9ClFNO | 95.000 | Cl.NC1COCC1F | 0.25g | 600864294
4-FLUOROTETRAHYDROFURAN-3-AMINE HYDROCHLORIDE | AstaTech | 2089325-76-6141.570 | C4H9ClFNO | 95.000 | Cl.NC1COCC1F | 0.25g | 600864294
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Medchemexpress LLC Hexyl nicotinate | 23597-82-2 | 99.0% | 100 MG
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Hexyl nicotinate is a nicotinic acid ester used as a laboratory reagent in biochemical and pharmacological research. It is typically supplied as a liquid with documented purity, molecular properties, and defined storage and solubility recommendations.
- Purity 98.96%.
- Molecular formula C12H17NO2.
- Molecular weight 207.27 g/mol.
- Appearance colorless to light yellow liquid; density 1.02 g/cm3.
- Solubility DMSO soluble at 100 mg/mL; in vivo formulation ≥ 2.5 mg/mL in 10% DMSO with SBE-β-CD in saline.
- Storage pure form: -20°C (3 years) or 4°C (2 years); in solvent: -80°C (6 months).
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eMolecules 2112738-58-4 | DSPE-PEG4-acid | Broadpharm | MFCD30828702 | 1010.338 | C52H100NO15P | 97.000 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)COCCOCCOCCOCCC(O)=O)OC(=O)CCCCCCCCCCCCCCCCC | 100mg | 349512642
DSPE-PEG4-acid | Broadpharm | 2112738-58-4 | MFCD30828702 | 1010.338 | C52H100NO15P | 97.000 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)COCCOCCOCCOCCC(O)=O)OC(=O)CCCCCCCCCCCCCCCCC | 100mg | 349512642
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eMolecules Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine | Broadpharm |670.073 | C40H79NO6 | 0.000 | CCCCCCCCC(CCCCCC)C(=O)OCCOCCNCCOCCOC(=O)C(CCCCCC)CCCCCCCC | 50mg | 718091569
Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine | Broadpharm |670.073 | C40H79NO6 | 0.000 | CCCCCCCCC(CCCCCC)C(=O)OCCOCCNCCOCCOC(=O)C(CCCCCC)CCCCCCCC | 50mg | 718091569
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Sigma Aldrich Fine Chemicals Biosciences 2-Methoxyethanol ReagentPlus(R), >=99.0%, contains 50 ppm BHT as stabilizer | 109-86-4 | MFCD00002867 | 500ML
2-Methoxyethanol ReagentPlus(R), >=99.0%, contains 50 ppm BHT as stabilizer | Purity: >=99.0% | Mol Wt: 76.09 | 109-86-4 | MFCD00002867 | 500ML
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eMolecules 2086689-03-2 | Aminooxy-PEG3-methyl ester | Broadpharm | MFCD30723260 | 251.279 | C10H21NO6 | 98.000 | COC(=O)CCOCCOCCOCCON | 100mg | 340376915
Aminooxy-PEG3-methyl ester | Broadpharm | 2086689-03-2 | MFCD30723260 | 251.279 | C10H21NO6 | 98.000 | COC(=O)CCOCCOCCOCCON | 100mg | 340376915
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Ambeed 1 4Oxazepan5one
1,4-Oxazepan-5-one, 10341-26-1, 97%
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Medchemexpress LLC Phen Green SK diacetate (5/6-mixture) | 234075-45-7 | 95.3% | 1 MG
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Phen Green SK diacetate (5/6-mixture) is a metal ion-sensitive fluorescent probe that can penetrate cell membranes. It reacts with various metal ions like Fe2+, Cd2+, Co2+, Ni2+, and Zn2+. When Phen Green SK diacetate chelates Fe2+, it causes fluorescence quenching, which can be reversed by adding a membrane-permeable chelator, reflecting changes in the intracellular chelatable iron pool.
- Metal ion-sensitive fluorescent probe.
- Can penetrate cell membranes.
- Reacts with a variety of metal ions including Fe2+, Cd2+, Co2+, Ni2+, and Zn2+.
- Chelates Fe2+, leading to fluorescence quenching that can be restored, indicating changes in the intracellular chelatable iron pool.
- Excitation/emission maxima are 507/532 nm.
- Used to detect intracellular Fe2+ levels.
- Can be used with a lipid peroxidation indicator dye to assess the ferroptosis state of cells.
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Matrix Scientific 1-BROMO-3-METHOXYPROPANE-25G
1-Bromo-3-methoxypropane, 98%; 25g,C4H9BrO, MFCD02258473, mw 153.02, [36865-41-5]
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