Sulfonyls
Medchemexpress LLC Benzenesulfonamide, 4-amino-N-2-thiazolyl- | 72-14-0 | 99.7% | 500 MG
Sulfathiazole is an orally active, organosulfur compound functioning as a short-acting sulfonamide antibiotic and an endocrine disruptor. It targets the steroidogenic pathway, enhancing CYP19 activity in human adrenal cells (H295R) and upregulating mRNA expression of CYP17, CYP19, and 3β-HSD. It also increases 17-estradiol (E2) production and exhibits endocrine-disrupting effects on aquatic organisms like the Japanese medaka fish. This product is a white to off-white solid with a molecular formula of C9H9N3O2S2 and a molecular weight of 255.32. It is intended for research use only.
- Purity of 99.71%
- Orally active sulfonamide antibiotic
- Targets steroidogenic pathway by enhancing CYP19 activity
- Appears as a white to off-white solid
- Recommended for long-term storage in powder form at -20°C for 3 years or 4°C for 2 years
- Recommended for storage in solution at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Sulfapyridine (Standard) | 144-83-2 | 99.9% | 100 MG
Sulfapyridine (Standard) is an analytical standard intended for research and analytical applications. This compound is a major metabolite of Sulfasalazine and functions as a sulfonamide antibiotic agent, exhibiting antibacterial, anti-inflammatory, and anti-rheumatic activities. It serves as a reference standard for assays and is commonly used in qualitative, quantitative, and methodological research experiments.
- Analytical standard for research and analytical applications
- Functions as a sulfonamide antibiotic agent
- Exhibits antibacterial, anti-inflammatory, and anti-rheumatic activities
- Inhibits P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM
- Used in HPLC, GC, and MS research experiments
- Inhibits production of IL-8, CXCL1, and MCP-1 in synovial cells of rheumatoid arthritis
- Inhibits systemic allergic reactions in vivo
Medchemexpress LLC Sulfadiazine | 68-35-9 | 99.9% | 10 MM * 1 ML
Sulfadiazine is a sulfonamide antibiotic with antimalarial activity, primarily used for toxoplasmosis research. This product is intended for research use only and has not been fully validated for medical applications.
- Functions as a sulfonamide antibiotic
- Exhibits antimalarial activity
- Suitable for toxoplasmosis research
- Supplied as a white to off-white solid
- High purity of 99.9%
Medchemexpress LLC Sulfadiazine | 68-35-9 | 99.9%
Sulfadiazine is a sulfonamide antibiotic with antimalarial activity, primarily used for toxoplasmosis research.
- Functions as a sulfonamide antibiotic
- Exhibits antimalarial properties
- Utilized in toxoplasmosis research
- Demonstrates activity against Toxoplasma gondii in various cell lines (e.g., MRC5, Vero)
- Effectiveness evaluated in in vivo models against T. gondii strains
Medchemexpress LLC Sulfadiazine | 68-35-9 | 99.9% | 1 G
Sulfadiazine is a sulfonamide antibiotic with antimalarial activity, primarily used for toxoplasmosis research. With a molecular formula of C10H10N4O2S and a molecular weight of 250.28, this compound targets bacterial and parasitic organisms, functioning within the anti-infection pathway. It is available in solid form.
- Purity is 99.89%.
- Powder is stable for 3 years at -20°C and 2 years at 4°C.
- In solvent, stable for 2 years at -80°C and 1 year at -20°C.
- In vitro solubility: soluble in DMSO (≥ 50 mg/mL) but insoluble in H₂O.
- In vivo solubility options include 10% DMSO with various diluents.
- IC₅₀ and target information for Toxoplasma is available.
Medchemexpress LLC Sulfathiazole | 72-14-0 | MFCD00005319 | 99.7% | 1 G
Sulfathiazole is an orally active endocrine disruptor that targets the steroidogenic pathway. It specifically enhances the activity of CYP19 in human adrenal cancer cells (H295R) and upregulates the mRNA expression of CYP17, CYP19, and 3β-HSD. It also increases the production of 17-estradiol (E2) and demonstrates endocrine disrupting effects on aquatic organisms like the Japanese medaka fish.
- Targets the steroidogenic pathway
- Enhances CYP19 activity in human adrenal cancer cells (H295R)
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD
- Increases production of 17-estradiol (E2)
- Demonstrates endocrine disrupting effects on aquatic organisms
- Can inhibit copper corrosion in 0.1 M NaCl solution
- Increases plasma 17-estradiol concentrations in male Japanese medaka models
Medchemexpress LLC Sulfadiazine sodium | 547-32-0 | 98.0% | 5 G
Sulfadiazine sodium is a sulfonamide antibiotic with antimalarial activity, utilized in toxoplasmosis research.
- Sulfonamide antibiotic with antimalarial activity
- Useful for toxoplasmosis research
- Purity of 98.0%
- Molecular formula: C10H9N4NaO2S
- Molecular weight: 272.26
- Appears as a white to off-white solid
- Store solid at 4°C, protected from light, under nitrogen
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Sulfapyridine | 144-83-2 | MFCD00038036 | 99.9% | 1 G
Sulfapyridine is a sulfonamide antibiotic that is a major metabolite of Sulfasalazine. It acts as an antibiotic agent by inhibiting recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Beyond its antibacterial properties, Sulfapyridine also exhibits anti-inflammatory and anti-rheumatic activities.
- Inhibits IL-8, CXCL1, and MCP-1 production in synovial cells
- Active against Y. enterocolitica and Salmonella
- Significantly inhibits systemic allergic reactions in rats
- For research use only
Selleck Chemical LLC Sodium sulfadiazine S4634-500mg
Sodium Sulfadiazine (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine an intermediate-acting bacteriostatic synthetic sulfanilamide derivative
eMolecules 4-Amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide | Combi-Blocks | 68-35-9 | MFCD00006065 | 250.280 | C10H10N4O2S | 98.000 | Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1 | 5g | 296391758
4-Amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide | Combi-Blocks | 68-35-9 | MFCD00006065 | 250.280 | C10H10N4O2S | 98.000 | Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1 | 5g | 296391758
