Sulfoxides
Medchemexpress LLC Kv3 modulator 2 | 2101321-76-8 | 99.9% | 379.41 g·mol⁻¹ | C21H21N3O4 | 5 MG
Kv3 modulator 2 is a small-molecule modulator of Kv3 voltage-gated potassium channels with reported analgesic activity. It is provided for laboratory research use and is characterized by a defined molecular formula and molecular weight, and high purity suitable for preclinical studies.
- High purity (99.9%).
- Available in small research quantities (example: 5 mg).
- Molecular formula C21H21N3O4; molecular weight 379.41 g·mol⁻¹.
- Reported Kv3 channel modulatory activity with analgesic effects.
- For research use only; not for human or clinical use.
Medchemexpress LLC Nourseothricin (sulfate) | 96736-11-7 | 99.9% | 1 G
Nourseothricin sulfate is a broad-spectrum antibiotic that inhibits protein biosynthesis in prokaryotic cells and destroys the outer membrane of Gram-negative bacteria. It also functions as a selective marker for *Fonsecaea pedrosoi* and is effective for a diverse range of organisms including bacteria, yeast, filamentous fungi, and plant cells.
- Broad-spectrum antibiotic
- Destroys outer membrane of Gram-negative bacteria
- Inhibits protein biosynthesis in prokaryotic cells
- Inhibits growth of eukaryotes such as fungi
- Selective marker for *Fonsecaea pedrosoi*
- Used as an elective marker for various organisms
Medchemexpress LLC 1-Butanesulfonic acid, sodium salt | 2386-54-1 | MFCD00007540 | 98.0% | 160.17 g/mol | C4H9NaO3S | 1 G
Sodium butane-1-sulfonate (sodium 1-butanesulfonate) is an anionic sulfonate salt supplied as a white to off-white solid. It is used primarily as an ion-pairing reagent or mobile-phase additive in chromatographic separations, for example to improve separation of arsenic and selenium species. Typical purity is 98.0% and it is available in small laboratory pack sizes.
- Anionic sulfonate suitable for ion-pairing in HPLC.
- Improves separation of arsenic and selenium species.
- White to off-white solid with stated purity of 98.0%.
- Molecular weight 160.17 g/mol; formula C4H9NaO3S.
- Supplied in small laboratory pack sizes for analytical use.
Medchemexpress LLC (+)-LRH-1 modulator-1 | 00-00-0 | 99.4% | C28H36N2O2S | 10MG
(+)-LRH-1 modulator-1 is the (+)-stereoisomer of an LRH-1 modulator and functions as a potent agonist of liver receptor homolog-1 (LRH-1). It modulates inflammatory signaling in intestinal organoid models by inducing IL-10 and reducing IL-1β and TNFα. The compound is provided as a high-purity research-grade small molecule for cellular and biochemical studies of LRH-1 pathways.
- Potent LRH-1 modulator/agonist for receptor pharmacology studies.
- Induces anti-inflammatory cytokine IL-10 in organoid models.
- Reduces proinflammatory cytokines IL-1β and TNFα in assays.
- High purity suitable for cellular and biochemical experiments.
- Available in multiple small-scale quantities for research use.
Medchemexpress LLC Dl-sulforaphane n-acetyl-l-cysteine | 334829-66-2 | 99.9% | 340.48 g/mol | C11H20N2O4S3 | 5 MG
DL-Sulforaphane N-acetyl-L-cysteine is a sulforaphane metabolite used in research as an orally active histone deacetylase (HDAC) inhibitor. It is reported to have an extended half-life and improved blood-brain barrier permeability versus the parent compound, and has been used to study autophagy, HDAC activity, and anticancer mechanisms. Supplied as a high-purity solid for laboratory research.
- Orally active HDAC inhibitor and sulforaphane metabolite.
- Longer half-life and improved blood-brain barrier permeability compared with parent compound.
- Reported to induce autophagy, cell-cycle arrest, and apoptosis in certain cancer cell lines.
- High-purity solid suitable for research applications.
- Soluble in DMSO; store powder frozen for long-term stability.
Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | >99.0% | C27H34N6O2 | 1 MG
IL-17 modulator 4 is a proagent of IL-17 modulator 1, an orally active and highly efficacious IL-17 modulator. This compound is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome. It modulates IL-17A protein-protein interaction by stabilizing the conformation of the IL-17A dimer, preventing binding to the IL-17RA receptor and inhibiting the IL-17A-mediated signaling pathway. It demonstrates favorable pharmacokinetic properties with excellent oral bioavailability.
- Modulates IL-17A protein-protein interaction
- Stabilizes IL-17A dimer conformation
- Inhibits IL-17A-mediated signaling pathway
- Potential for research in inflammation and autoimmune diseases
- Exhibits good pharmacokinetic properties in rat models
- Offers high oral bioavailability
Medchemexpress LLC Nourseothricin (sulfate) | 96736-11-7 | 99.9% | 500 MG
Nourseothricin (sulfate) is a broad-spectrum polycationic antibiotic that destroys the outer membrane of Gram-negative bacteria. It functions by inhibiting protein biosynthesis in prokaryotic cells and significantly suppressing the growth of eukaryotes such as fungi. It is a dominant selective marker for Fonsecaea pedrosoi and can be utilized as a selective marker for a diverse range of organisms, including bacteria, yeast, filamentous fungi, and plant cells.
- Broad-spectrum antibiotic
- Destroys outer membrane of Gram-negative bacteria
- Inhibits protein biosynthesis in prokaryotic cells
- Suppresses growth of eukaryotes such as fungi
- Selective marker for Fonsecaea pedrosoi, bacteria, yeast, filamentous fungi, and plant cells
- Mixture of several Streptothricins, mainly D and F
- Can create channels in the outer membrane of bacteria
Medchemexpress LLC Sulforaphane | 4478-93-7 | MFCD00016766 | 99.0% | 177.29 | 50 MG
Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway, promoting transcription of tumor-suppressing proteins and inhibiting HDACs. It protects the heart by activating the Keap1/Nrf2/ARE pathway and inducing HO-1 expression, and suppresses high glucose-induced pancreatic cancer via AMPK-dependent signal transmission. It exhibits both anticancer and anti-inflammatory properties.
- Induces cell cycle arrest and apoptosis.
- Inhibits growth re-initiation and decreases cell viability.
- Reduces apoptotic cells and pro-apoptotic proteins.
- Activates Keap1/Nrf2/ARE pathway and induces HO-1 expression.
- Inhibits mammary tumor formation.
- Reduces incidence and weight of DMBA-induced mammary tumors.
Medchemexpress LLC 5-HT1A modulator 2 hydrochloride | 3880-76-0 | 99.69% | 213.70 | 10 MM * 1 ML
5-HT1A modulator 2 hydrochloride is a derivative of 8-OH-DPAT (HY-112061), acting as a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding.
- Modulator of 5-HT1A
- Derivative of 8-OH-DPAT
- Binding Ki of 53 nM for 5-HT1A
Cayman Chemical SulIndac sulfon 10mg
An oxidized metabolite of sulindac that is produced in many mammals but minimally in mice and rats; generally considered to be inactive against COX enzymes, although it can reduce azoxymethane-induced colon cancer in rats; inhibits aldose reductase (IC50 = 367 nM) in vitro