Sulfoxides
Medchemexpress LLC 5-HT1A modulator 2 hydrochloride | 3880-76-0 | 99.69% | 213.70 | 10 MM * 1 ML
5-HT1A modulator 2 hydrochloride is a derivative of 8-OH-DPAT (HY-112061), acting as a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding.
- Modulator of 5-HT1A
- Derivative of 8-OH-DPAT
- Binding Ki of 53 nM for 5-HT1A
Medchemexpress LLC Sulindac | 38194-50-2 | 99.68% | C20H17FO3S | 100 MG
Sulindac (MK-231) is an orally active nonsteroidal anti-inflammatory agent and an immunomodulatory agent. It is used for the research of arthritis of the spine, gouty arthritis, and various cancers, including colorectal cancer (CRC) and lung cancer.
- Store powder at -20°C for 3 years or 4°C for 2 years.
- Store in solvent at -80°C for 2 years or -20°C for 1 year.
Medchemexpress LLC Mutant p53 modulator-1 | 2746371-35-5 | 99.9% | C27H32F4N8O2 | 50 MG
Mutant p53 modulator-1 is a mutant p53 modulator that reduces the progression of cancers containing a p53 mutation.
- Molecular weight: 576.59
- Appearance: Solid
- Color: Light yellow to brown
- Solubility in DMSO: 100 mg/mL (173.43 mM)
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC AHL modulator-1 | 942296-18-6 | 99.2% | 298.13 | 25 MG
AHL modulator-1 is a compound that modulates N-acylated L-homoserine lactone (AHL) activity. It exhibits both agonism and antagonism in cellulase activity and potato maceration. This product is suitable for laboratory research applications.
- Soluble in DMSO
- Stable as powder at -20°C for 3 years
- Stable as powder at 4°C for 2 years
- Stable in solvent at -80°C for 6 months
- Stable in solvent at -20°C for 1 month
Medchemexpress LLC GLP-1R modulator C16 | 875005-43-9 | 98.7% | C21H26ClFN2O3 | 50 MG
GLP-1R modulator C16 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 8.43 ± 3.82 μM).
- Enhances GLP-1 binding to GLP-1R.
- Acts via a transmembrane site.
- High purity of 98.7% confirmed by LCMS.
- Recommended storage conditions for powder: -20°C for 3 years, 4°C for 2 years.
- Recommended storage conditions for in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC 3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride | 2749504-65-0 | 99.9% | 307.86 | 5 MG
This product is a laboratory chemical, 3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride, intended for research use only and suitable for the manufacture of substances. It should be handled by suitably qualified and experienced scientists in appropriately equipped and authorized facilities. The substance is stable under recommended storage conditions but is incompatible with strong acids/alkalis and strong oxidizing/reducing agents. It is not classified as a hazardous substance or mixture.
- Identified for laboratory use and substance manufacturing.
- Stable under recommended storage conditions.
- High purity of 99.9%.
- Molecular formula C18H26CINO.
- Powder storage: -20°C for 3 years, 4°C for 2 years.
- In solvent storage: -80°C for 6 months, -20°C for 1 month.
- Not a hazardous substance or mixture.
Medchemexpress LLC Mutant p53 modulator-1 | 2746371-35-5 | 99.89% | C27H32F4N8O2 | 25 MG
Mutant p53 modulator-1 is a compound that acts as a mutant p53 modulator. It reduces the progression of cancers containing a p53 mutation. This product is for research use only and not intended for patient use.
- Reduces progression of cancers with p53 mutation
- For research use only
- Powder storage at -20°C for 3 years, or 4°C for 2 years
- In solvent storage at -80°C for 6 months, or -20°C for 1 month
- Appears as a light yellow to brown solid
- Purity of 99.89% by HPLC
Medchemexpress LLC mGluR3 modulator-1 | 374548-18-2 | C16H21N3O | 5 MG
mGluR3 modulator-1 (compound 3) is a mGluR3 modulator with an EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 Calcium Mobilization Assay. It is intended for research use only.
- Solid, white to off-white appearance
- Purity of 98.67%
- Molecular weight: 271.36
- Can be stored as powder at -20°C for 3 years, or 4°C for 2 years
- Can be stored in solvent at -80°C for 6 months, or -20°C for 1 month
- Soluble in DMSO at 125 mg/mL
Medchemexpress LLC GPR120 modulator 2 | 1050506-87-0 | 97.1% | 387.88 | C20H18ClNO3S | 10 MG
GPR120 modulator 2 is a small-molecule research compound that modulates the free fatty acid receptor GPR120 and is intended for in vitro pharmacology and metabolic signaling studies.
- Targets the free fatty acid receptor GPR120.
- Molecular formula C20H18ClNO3S and molecular weight 387.88.
- CAS number 1050506-87-0 for unambiguous identification.
- High purity (97.1%) suitable for research applications.
- Available in small pack sizes, including 10 mg.
- Storage: powder at -20°C for long-term stability, 4°C short term; in solvent store at -80°C.
Medchemexpress LLC Phenol, 2,2'-sulfinylbis[4,6-dichloro- | 844-26-8 | 99.0% | 372.05 | 50 MG
Bithionol sulfoxide is an anti-infection agent for parasites, with mutagenic activity. It can be used in research of parasite infections such as paragonimiasis, flukes, and cestodes infection.
- Shows toxicity to *Neoparamoeba spp* parasites in sea water.
- Exhibits mutagenic activity in strains TA98 and TA100.
- Demonstrates efficacy against natural rumen fluke infections in dairy cattle.
- Supplied as a white to off-white solid.
- Storage conditions for powder: -20°C for 3 years, 4°C for 2 years.
- Storage conditions in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC Elafibranor sulfoxide | 95.0% | 400.49 | 25 MG
Elafibranor (GFT505) sulfoxide is a sulfoxide metabolite of Elafibranor (HY-16737). Elafibranor is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis.
- Purity: 95.0%
- Molecular weight: 400.49
- Formula: C22H24O5S
- Appearance: Solid
- Color: Light yellow to yellow
- Solubility (in vitro): 100 mg/mL (DMSO)
- Storage (powder): -20°C 3 years, 4°C 2 years
- Storage (in solvent): -80°C 6 months, -20°C 1 month
- Research use only
Medchemexpress LLC Sonidegib metabolite 50mg | 1221722-10-6 | 296.24 g·mol⁻¹ | C15H11F3O3 | 50 MG
Sonidegib metabolite M48 (2-methyl-3-[4-(trifluoromethoxy)phenyl]benzoic acid) is the primary circulating metabolite of sonidegib, supplied as a research-grade reference standard for pharmacokinetic, metabolic, and analytical studies.
- For research use only; not for human or clinical use.
- High purity: 98.0%.
- White to off-white solid, stable under recommended storage.
- Comprehensive analytical data available (COA, HNMR, LC-MS).
- Recommended storage: room temperature (solid) for up to 3 years; in solvent: -80°C for 2 years, -20°C for 1 year.
- Suitable as a reference standard for PK and metabolism studies.
Medchemexpress LLC GLP-1R modulator L7-028 | 2648317-95-5 | 99.5% | C24H28N2O3 | 25 MG
GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM).
- Enhances GLP-1 binding to GLP-1R
- Functions as an allosteric modulator
- Acts via a transmembrane site
- Molecular weight: 392.49
- Appearance: solid, white to off-white
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO: 100 mg/mL (254.78 mM)
Medchemexpress LLC Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)- | 2097787-75-0 | 99.0% | 308.40 | 5 MG
Nur77 modulator 3 (HY-162147) is a chemical compound intended for research use only. It has a molecular weight of 308.40 and exhibits a high purity of 99.01% via HPLC analysis. This compound is identified by its CAS Number 2097787-75-0 and the chemical name Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)-.
- Provided as a white to off-white solid
- Structure confirmed by ¹H NMR and LCMS
- High purity of 99.01% verified by HPLC
- Powder storage recommended at -20°C for up to 3 years
- In-solvent storage recommended at -80°C for 6 months or -20°C for 1 month
- Complies with specified quality standards
Medchemexpress LLC Mutant p53 modulator-1 | 2746371-35-5 | 99.9% | C27H32F4N8O2 | 1 ML
Mutant p53 modulator-1 is a compound that acts as a modulator of mutant p53. It has been shown to reduce the progression of cancers that possess a p53 mutation. This compound is identified as 231B in patent WO2021231474A1.
- Molecular weight: 576.59
- Appearance: Solid
- Color: Light yellow to brown
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: Powder at -20°C for 3 years, 4°C for 2 years. In solvent at -80°C for 6 months, -20°C for 1 month
- Solubility (in vitro): 100 mg/mL (173.43 mM) in DMSO (requires sonication; hygroscopic DMSO significantly impacts solubility, use newly opened DMSO)
- 1
- 2