Cinnamic acids and derivatives
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 100 MG
Ferulic acid 4-O-sulfate, also known as Ferulic acid 4-sulfate, is a metabolite of Ferulic acid that has been observed to relax arteries and decrease blood pressure in mice.
- In vitro: This compound, at concentrations ranging from 0.1 to 30 μM, elicited significant concentration-dependent relaxations in the aorta, femoral, and saphenous arteries of mice.
- In vivo: When administered intravenously to male Swiss mice at dosages of 16.13 and 161.3 μg/kg, ferulic acid 4-O-sulfate demonstrated the ability to relax arteries and lower blood pressure, with a significant decrease in mean arterial pressure (MAP) observed immediately post-injection.
Medchemexpress LLC M-coumaric acid (standard) | 588-30-7 | 99.9% | 164.16 | 10 MG
M-coumaric acid (standard) | 588-30-7 | 99.9% | 164.16 | 10 MG
eMolecules 117113-98-1 | 4-(4-Fluorobenzyloxy)benzyl alcohol | Oakwood Chemical | MFCD00173648 | 232.254 | C14H13FO2 | 98.000 | OCc1ccc(OCc2ccc(F)cc2)cc1 | 1g | 537669244
4-(4-Fluorobenzyloxy)benzyl alcohol | Oakwood Chemical | 117113-98-1 | MFCD00173648 | 232.254 | C14H13FO2 | 98.000 | OCc1ccc(OCc2ccc(F)cc2)cc1 | 1g | 537669244
Medchemexpress LLC cis-p-Coumaric acid | 4501-31-9 | 164.16 | 5 MG
cis-p-Coumaric acid, also known as cis-4-Hydroxycinnamic acid, is the cis-form of p-Coumaric acid. This compound is found in higher concentrations in viable groundnut seeds compared to non-viable ones.
- Exhibits oral activity.
- Inhibits cell proliferation.
- Promotes apoptosis.
Selleck Chemical LLC 2-Methoxycinnamic acid
2-Methoxycinnamic acid (AI3-11206) is a cinnamic acid with magnetic properties
Medchemexpress LLC p-Coumaric acid (trans-4-hydroxycinnamic acid) | 501-98-4 | 164.16 | 10 G
p-Coumaric acid, an isomer of cinnamic acid, demonstrates diverse biological activities including antibacterial, anti-inflammatory, antioxidant, and anti-tumor effects. It has been shown to inhibit cell proliferation and promote apoptosis, making it a subject of interest in various research applications.
- Inhibits proliferation of A375 and B16 cells.
- Promotes cell apoptosis in human and mouse melanoma cells.
- Exhibits antibacterial activity against gram-negative and gram-positive bacteria.
- Reduces polyp incidence and precancerous lesions in animal models.
- Alleviates doxorubicin-induced nephrotoxicity by inhibiting oxidative stress, inflammation, and apoptosis.
- Modulates cell cycle progression and protein expression in A375 and B16 cells.
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.1% | 274.25 | 1 ML
Ferulic acid 4-O-sulfate is a metabolite of ferulic acid. It relaxes arteries and lowers blood pressure in mice. This product is for research use only and not sold to patients.
- Causes significant concentration-dependent relaxations in mouse aorta, femoral, and saphenous arteries (in vitro).
- Relaxes arteries and lowers blood pressure in mice (in vivo).
- Significantly decreases mean arterial pressure (MAP) immediately after intravenous injection in male Swiss mice.
Accela Chembio Inc 3-(trifluoromethyl)cinnamic Acid | Predominantly Trans | 100g | 779-89-5 | MFCD00004393 | 97+% | Shelf Life: 1440 Days | Light Sensitive
3-(trifluoromethyl)cinnamic Acid | Predominantly Trans | 100g | 779-89-5 | MFCD00004393 | 97+% | Shelf Life: 1440 Days | Light Sensitive
Waters Corp Ion Chamber, CI, MS System, Replacement Part
This replacement Ion Chamber is designed for Chemical Ionization (CI) applications within an MS System. It functions as a critical component, used specifically on the Xevo TQ-GC system.
- Categorized as a replacement parts kit
- Mechanical type
- Used in MS (Mass Spectrometry) systems
- Replaced as required
Medchemexpress LLC cis-Ferulic acid 4-O-β-D-glucopyranoside | 94942-20-8 | 356.32 | 5 MG
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycosid, which can be isolated from Nitraria sibirica. This compound exhibits antioxidant activity and a potent inhibitory effect on Phosphatase PTP1B.
- Exhibits antioxidant activity.
- Potent inhibitory effect on Phosphatase PTP1B.
![eMolecules 953769-46-5 | Sotuletinib | Ambeed | MFCD28142668 | 398.480 | C20H22N4O3S | 98.000 | CNC(=O)c1cc(Oc2ccc3nc(N[C@@H]4CCCC[C@H]4O)sc3c2)ccn1 | 1mg | 682927965](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502417835.JPG-250.jpg)
eMolecules 953769-46-5 | Sotuletinib | Ambeed | MFCD28142668 | 398.480 | C20H22N4O3S | 98.000 | CNC(=O)c1cc(Oc2ccc3nc(N[C@@H]4CCCC[C@H]4O)sc3c2)ccn1 | 1mg | 682927965
Sotuletinib | Ambeed | 953769-46-5 | MFCD28142668 | 398.480 | C20H22N4O3S | 98.000 | CNC(=O)c1cc(Oc2ccc3nc(N[C@@H]4CCCC[C@H]4O)sc3c2)ccn1 | 1mg | 682927965
Medchemexpress LLC Trans-Cinnamic acid | 140-10-3 | 148.16 | 500 MG
Trans-Cinnamic acid is a natural antimicrobial that demonstrates a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1.
- Natural antimicrobial agent.
- Exhibits moderate inhibition against various fish pathogens.
- More effective on bacteria when the pH of the culture media is not neutralized.
- For research use only.
Apexbio Technology LLC Sodium ferulic 24276-84-4 500mg
Sodium ferulic (CAS 24276-84-4) is a small molecule inhibitor targeting fibroblast growth factor receptors specifically FGFR1 and FGFR2 It demonstrates inhibitory activity with IC50 values of 3 78 M for FGFR1 and 12 5 M for FGFR2 At the cellular level sodium ferulic suppresses intracellular signaling pathways involved in cell proliferation This compound is utilized in biomedical research to investigate signaling mechanisms and to assess therapeutic potential in disease models such as cancer
Apexbio Technology LLC BIBF 1202 894783-71-2 5mg
BIBF 1202 (CAS 894783-71-2) is a carboxylate metabolite derivative of BIBF 1120 characterized as a selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2) kinase In biochemical assays BIBF 1202 demonstrates inhibitory activity against VEGFR2 kinase with an IC50 of 62 nM This compound is frequently employed in studies investigating the regulation of the VEGFR2 signaling pathway and its role in endothelial cell function Additionally BIBF 1202 is utilized in preclinical models related to tumor angiogenesis and associated pharmacological research
Medchemexpress LLC Ferulic acid methyl ester | 2309-07-1 | 99.9% | 208.21 g/mol | C11H12O4 | 1 G
Ferulic acid methyl ester (methyl ferulate) is the methyl ester derivative of ferulic acid used as a research reagent. It is reported as a p38 MAPK inhibitor with anti-inflammatory and antioxidant properties and is applied in studies of autophagy and neurological disease. The compound is cell membrane and brain permeable and modulates COX-2, p-p38, and p-JNK signaling.
- CAS number 2309-07-1
- Chemical formula C11H12O4
- Molecular weight 208.21 g/mol
- Typical purity ~99.9% (rounded)
- Available as solid and 10 mM solution in DMSO
- Reported p38 MAPK inhibitor with anti-inflammatory activity
- Useful for autophagy and neurological disease research