Cinnamic acids and derivatives
Medchemexpress LLC Tyrphostin A1 | 2826-26-8 | 99.0% | 184.19 | 100 MG
Tyrphostin A1 inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells. It causes a dose-dependent decrease of IL-12 p40 and blocks CD40L-induced translocation of NF-κB to the nucleus, reducing activation of the IL-12 p40 gene. This compound is a weaker inhibitor of TK, often used to differentiate TK-mediated effects from other non-specific effects.
- Inhibits CD40L-stimulated IL-12 production
- Reduces antigen-induced generation of Th1 cells
- Blocks CD40L-induced translocation of NF-κB to the nucleus
- Attenuates experimental allergic encephalomyelitis (EAE) in SJL/J mice
- Useful for differentiating TK-mediated effects from non-specific effects
- For research use only
Medchemexpress LLC Trans-Cinnamic acid | 140-10-3 | 148.16 | 25 MG
Trans-Cinnamic acid is a natural antimicrobial with a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1. It exhibits broad antimicrobial activity against various fish pathogens and is more effective on bacteria when the pH of the culture media is not neutralized.
- Targeted activity against bacterial and endogenous metabolites
- Inhibits various fish pathogens
- Stable for 3 years at room temperature
- Stable in solvent for 2 years at -80°C or 1 year at -20°C
Bruker Daltonics alpha-Cyano-4-hydroxycinnamic acid | 28166-41-8 | MFCD00004204
alpha-Cyano-4-hydroxycinnamic acid | Mol Wt: 189.17 | 28166-41-8 | MFCD00004204
![Medchemexpress LLC 2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile | 116313-73-6 | 98.7% | 231.16 g/mol | C10H5N3O4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247989.png-250.jpg)
Medchemexpress LLC 2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile | 116313-73-6 | 98.7% | 231.16 g/mol | C10H5N3O4 | 25 MG
Tyrphostin AG 1288 is a small-molecule tyrosine kinase inhibitor used in biochemical and cellular research to probe tyrosine kinase-dependent signaling pathways, ICAM1 expression, and TNFα-mediated cytotoxicity. It is supplied as a high-purity research reagent intended for in vitro assays.
- High purity suitable for analytical and cell-based assays.
- Useful for investigating tyrosine kinase signaling pathways.
- Inhibits ICAM1 expression and TNFα-mediated cytotoxicity in vitro.
- Supplied as a stable, solid reagent for easy handling and storage.
- Batch-tested with a certificate of analysis for lot verification.
- Compatible with common solvents for assay formulation.
eMolecules 2699937-04-5 | Medchem Express | MRL-494 (hydrochloride) | 5mg | 552386588 | HY-128773A | 659.13 | C26H36ClFN16O2
Medchem Express | Apramycin (sulfate) | 100mg | 446273816 | HY-B1329 | 65710-07-8 | 637.660 | C21H43N5O15S
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eMolecules 890839-10-8 | 4-(1,1-Dimethyl-1-methoxycarbonyl)methylphenylboronic acid pinacol ester | Combi-Blocks | MFCD18761362 | 304.190 | C17H25BO4 | 98.000 | COC(=O)C(C)(C)c1ccc(cc1)B1OC(C)(C)C(C)(C)O1 | 1g | 232310038
4-(1,1-Dimethyl-1-methoxycarbonyl)methylphenylboronic acid pinacol ester | Combi-Blocks | 890839-10-8 | MFCD18761362 | 304.190 | C17H25BO4 | 98.000 | COC(=O)C(C)(C)c1ccc(cc1)B1OC(C)(C)C(C)(C)O1 | 1g | 232310038
Accela Chembio Inc 4-(dimethylamino)cinnamic Acid | 5g | 1552-96-1 | MFCD00004397 | 97+% | Shelf Life: 1260 Days | Light Sensitive
4-(dimethylamino)cinnamic Acid | 5g | 1552-96-1 | MFCD00004397 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Medchemexpress LLC Ozagrel hydrochloride | 78712-43-3 | 99.9% | 50 MG
Ozagrel hydrochloride (OKY-046 hydrochloride) is a highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. It exerts anti-platelet aggregation, vasodilation, and anti-inflammatory effects by inhibiting TXA2 production and increasing prostacyclin (PGI2) production. This product is intended for research use only and can be utilized for studies related to ischemic stroke, asthma, and thromboembolic diseases.
- Highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor
- Exerts anti-platelet aggregation effects
- Promotes vasodilation
- Provides anti-inflammatory effects
- Inhibits TXA2 production
- Increases prostacyclin (PGI2) production
- Useful for research in ischemic stroke
- Useful for research in asthma
- Useful for research in thromboembolic diseases
Sigma Aldrich Fine Chemicals Biosciences SB-366791 >=98% (HPLC), powder | 472981-92-3 | MFCD01033818 | 25MG
SB-366791 >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 287.74 | 472981-92-3 | MFCD01033818 | 25MG
eMolecules 614-60-8 | 2-Hydroxycinnamic acid | Combi-Blocks | MFCD00004379 | 164.160 | C9H8O3 | 97.000 | OC(=O)\C=C\c1ccccc1O | 25g | 528671053
2-Hydroxycinnamic acid | Combi-Blocks | 614-60-8 | MFCD00004379 | 164.160 | C9H8O3 | 97.000 | OC(=O)\C=C\c1ccccc1O | 25g | 528671053
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | MFCD00020189 | 98.0% | 170.17 g/mol | C10H6N2O | 10 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor used as a research reagent to investigate EGFR signaling and related pathways. The compound is supplied as a light yellow to yellow solid with high reported purity and is offered in multiple solid sizes and DMSO solution formats.
- Inhibits EGFR kinase; reported IC50 ≈ 560 μM
- Also exhibits GTPase inhibitory activity
- High purity for reproducible experimental results
- Available as solid and as 10 mM DMSO solution in multiple sizes
- Storage recommended: solid at 4°C under nitrogen; solutions at -80°C or -20°C