Cinnamic acids and derivatives
Cayman Chemical CurcumIn-d6 500ug
An internal standard for the quantification of curcumin by GC- or LC-MS
Medchemexpress LLC Curcumin 5-8 | 890984-26-6 | 98.58% | 339.39 | 100 MG
Curcumin 5-8 is a potent, orally active curcumin analog. It inhibits lipid droplet formation, increases autophagy, and inhibits apoptosis. It also improves insulin resistance and insulin sensitivity, and has been shown to ameliorate nonalcoholic fatty liver disease in mice.
- Decreases PA-induced SREBP1 expression and increases Bcl2/BAX expression in AML12 cells.
- Exhibits cytotoxic activity against B16, HUVEC, SiHa, U-87MG ATCC, and Vero cell lines.
- Ameliorates insulin resistance and hepatic steatosis in HFD-induced obese mice.
Selleck Chemical LLC a-cyano-4-hydroxycinnamic acid
4-Chloro- -cyanocinnamic acid ( -CHCA) is a classic monocarboxylate transporters (MCT) inhibitor -cyano-4-hydroxycinnamate (CHC) has a 10-fold selectivity for MCT1 compared to other MCTs
Selleck Chemical LLC Curcumin analog C1
Curcumin analog C1 (Curcumin analog Compound C1) is a potent transcription factor EB (TFEB) activator with promise for the prevention or treatment of Alzheimer s disease
Electron Microscopy Sciences Oil Red O, Certified C.I. DcRo-3 10 GR
Oil Red O is lysochrome (fat soluble dye) used demonstrate fat or lipids in fresh tissue sections. The polyazo group of dyes include the Oil Red, Sudan Red and the Sudan Blacks - all these dyes are interchangeable. Also known as Solvent Red 27, Sudan Red 5B.
Medchemexpress LLC M-coumaric acid | 588-30-7 | 99.8% | 164.16 | 1 ML
m-Coumaric acid is an endogenous metabolite and polyphenol that is formed from caffeic acid by gut microflora. It is a BBB-penetrant metabolite of chlorogenic acid and can stimulate cerebral nerves and evoke neurite outgrowth in hippocampal neuronal cells, promoting neuronal differentiation. It has also been shown to increase spontaneous locomotor activity in mice.
- Inhibits the oxidation of L-dopa by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Stimulates cerebral nerves in vitro
- Promotes neuronal differentiation
- Increases spontaneous locomotor activity
Medchemexpress LLC m-Coumaric acid | 588-30-7 | >99.8% | 164.16 | 500 MG
m-Coumaric acid | 588-30-7 | >99.8% | 164.16 | 500 MG
Selleck Chemical LLC Curcumin analog C1
Curcumin analog C1 (Curcumin analog Compound C1) is a potent transcription factor EB (TFEB) activator with promise for the prevention or treatment of Alzheimer s disease
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 10MM 1ML
SAR405 R enantiomer is the less active enantiomer of SAR405, a selective inhibitor of PIK3C3/Vps34, supplied for research use. It is offered as a ready-to-use 10 mM solution in DMSO or as a solid, and is used as a reference or control in studies of autophagy, vesicle trafficking, and related signaling pathways.
- Less active enantiomer of a PIK3C3/Vps34 inhibitor.
- High purity (~99.9%) for reliable experimental controls.
- Available as 10 mM solution in DMSO and multiple solid package sizes.
- Soluble in DMSO at 100 mg/mL; ultrasonication may be required.
- Storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
- Intended for research use only, not for clinical applications.
Apexbio Technology LLC Tyrphostin A1 2826-26-8 25mg
Tyrphostin A1 (CAS 2826-26-8) is a small molecule inhibitor targeting tyrosine kinase activity specifically involved in disrupting intracellular signaling pathways in immune cells It has been shown to interfere with CD40 ligand-induced signaling resulting in suppressed interleukin-12 (IL-12) secretion by macrophages and reduced differentiation of antigen-induced T helper 1 (Th1) cells Tyrphostin A1 is widely utilized in studies investigating cell-to-cell signaling immune response modulation and the mechanisms underlying inflammatory processes particularly in the context of autoimmune disease models
Selleck Chemical LLC (R)-(-)-JQ1 Enantiomer S2965-5mg
(R)-(-)-JQ1 Enantiomer is the stereoisomer of ( )-JQ1 ( )-JQ1 potently decreases expression of both BRD4 target genes whereas (R)-(-)-JQ1 Enantiomer has no effect
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | MFCD00020189 | 98.0% | 170.17 g·mol⁻¹ | C10H6N2O | 1 ML
Tyrphostin 8 is a small-molecule inhibitor that targets tyrosine kinases and GTPases and also inhibits calcineurin phosphatase activity. It is supplied at high purity for use in biochemical and cellular assays; chemical identifiers include CAS 3785-90-8, formula C10H6N2O, and molecular weight 170.17 g·mol⁻¹.