Coumarins and derivatives
Medchemexpress LLC 3-aminocoumarin (3-aminochromen-2-one) | 1635-31-0 | MFCD00016965 | 99.2% | 161.16 | C9H7NO2 | 250 MG
3-Aminocoumarin (3-aminochromen-2-one) is a coumarin-derived organic intermediate used in research and chemical synthesis. It functions as a building block for the preparation of metal complexes and other functionalized coumarin derivatives, and is supplied as a laboratory research reagent with recommended storage instructions to preserve stability.
- Coumarin-derived intermediate for organic synthesis.
- Suitable for synthesis of metal complexes and functionalized derivatives.
- Molecular formula C9H7NO2; molecular weight 161.16 g/mol.
- Recommended storage: solid at 4°C, protect from light; solutions -80°C (6 months) or -20°C (1 month).
- Provided as a research reagent; follow appropriate safety and handling procedures.
Apexbio Technology LLC 7-Amino-4-(trifluoromethyl)coumarin 53518-15-3 500mg
7-Amino-4-trifluoromethyl coumarin (CAS 53518-15-3) is a small-molecule antagonist targeting serotonin receptor subtype 1E (HTR1E) galanin receptor 2 (GALR2) and gamma receptor subtype 2 (GalR2) It is designed to antagonize these receptors thereby modulating receptor-mediated signaling pathways 7-Amino-4-trifluoromethyl coumarin exerts its biological activity primarily through receptor antagonism and inhibition of hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4) enzymatic activity In biochemical assays it demonstrates inhibitory activity toward HSD17B4 with reported bioactivity at approximately 21 M Based on these pharmacological properties 7-Amino-4-trifluoromethyl coumarin holds research potential in the investigation of protease activity receptor-mediated signaling and metabolic enzyme regulation
Cayman Chemical 3-Cyno-7-ethoxycoumarIn 50mg
A fluorogenic CYP450 substrate; a substrate for CYP1A1 and CYP1A2; metabolized to a lesser extent by CYP2D6 and CYP2C19; metabolized to 3-cyano-7-hydroxycoumarin and its fluorescence can be used to quantify CYP450 isoform activity
Sigma Aldrich Fine Chemicals Biosciences 7-Diethylamino-4-methylcoumarin 99% | 91-44-1 | MFCD00006864 | 100G
7-Diethylamino-4-methylcoumarin 99% | Purity: 99% | Mol Wt: 231.29 | 91-44-1 | MFCD00006864 | 100G
Selleck Chemical LLC 7-Methoxy-4-methylcoumarin S4780-25mg
7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label 7-Methoxy-4-methylcoumarin has an antimicrobial activitiy against both gram positive and gram negative bacterial stains 4-Methylherniarin displays good activity against B subtilis and S sonnei with IC50 of 11 76 g/ml and 13 47 g/ml respectively
Cayman Chemical 3-Cyno-7-ethoxycoumarIn 5mg
A fluorogenic CYP450 substrate; a substrate for CYP1A1 and CYP1A2; metabolized to a lesser extent by CYP2D6 and CYP2C19; metabolized to 3-cyano-7-hydroxycoumarin and its fluorescence can be used to quantify CYP450 isoform activity
Medchemexpress LLC Coumarin-C2-exo-BCN | 2488174-17-8 | 95.7% | 479.57 g·mol⁻¹ | C27H33N3O5 | 10 MG
Coumarin-C2-exo-BCN is a coumarin-derived fluorescent dye functionalized with an exo-BCN strained alkyne for bioorthogonal labeling via strain-promoted alkyne-azide cycloaddition (SPAAC). It is intended for catalyst-free conjugation to azide-containing biomolecules to generate fluorescent triazole-linked products.
- Fluorescent coumarin scaffold for sensitive detection.
- exo-BCN strained alkyne enables catalyst-free SPAAC with azides.
- Used to prepare fluorescent conjugates and label azide-containing biomolecules.
- Supplied as a solid with reported purity of ~95.7%.
Medchemexpress LLC 6-Bromocoumarin | 19063-55-9 | 225.04 | 5 G
6-Bromocoumarin is a potential anti-bacterial agent that shows no inhibition against 17β-HSD1 and exhibits affinity for α and β estrogen receptors. It is supplied as a white to off-white solid with a purity of 98.51% and a molecular weight of 225.04.
- Potential anti-bacterial agent
- Exhibits affinity for α and β estrogen receptors
- Solid appearance, white to off-white color
- Stable under recommended storage conditions
- For research use only
Medchemexpress LLC Coumarin-d4 | 185056-83-1 | 150.17 | 5 MG
Coumarin-d4 is the deuterium labeled version of Coumarin, which is the primary bioactive ingredient found in Radix Glehniae, also known as Beishashen in China. It exhibits various pharmacological activities, including anticancer, anti-inflammation, and antiviral properties. Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs. It is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC 7-hydrazinyl-4-methyl-2H-chromen-2-one | 113707-87-2 | MFCD09999551 | 97.1% | 190.20 | C10H10N2O2 | 100MG
Coumarin hydrazine is a fluorescent chemical probe used to label protein- and lipid-bound carbonyls in cells and biochemical assays. It reacts with aldehydes and ketones to form fluorescent hydrazones, producing a measurable signal suitable for live-cell and in vitro labeling when handled protected from light (λex = 420-450 nm; λem ≈ 468 nm).
- Fluorogenic probe for labeling protein- and lipid-bound carbonyls.
- Reacts with aldehydes and ketones to form fluorescent hydrazones.
- Excitation 420-450 nm; emission ≈468 nm.
- Molecular formula C10H10N2O2; molecular weight 190.20.
- Purity 97.1%; supplied as a 100 mg solid.
- Protect from light; in solvent store at -80°C for up to 6 months or at -20°C for up to 1 month.
Sigma Aldrich Fine Chemicals Biosciences 7-Methoxycoumarin suitable for fluorescence, >=98.0% (TLC) | 531-59-9 | MFCD00006876 | 500MG
7-Methoxycoumarin suitable for fluorescence, >=98.0% (TLC) | Purity: >=98.0% (TLC) | Mol Wt: 176.17 | 531-59-9 | MFCD00006876 | 500MG
Medchemexpress LLC Coumarin-3-carboxylic acid | 531-81-7 | MFCD00006852 | 99.9% | 190.15 g/mol | C10H6O4 | 500 G
Coumarin-3-carboxylic acid is an aromatic coumarin derivative (C10H6O4, MW 190.15 g/mol) commonly used as a fluorescence probe for detection of hydroxyl radicals and as a synthetic intermediate in organic and medicinal chemistry. It is supplied in high purity suitable for research and is available in a range of laboratory pack sizes.
- Used as a fluorescence probe for hydroxyl radical detection
- Serves as a synthetic intermediate for coumarin derivatives
- High purity suitable for analytical and research use
- Available in multiple laboratory pack sizes, including bulk options
- Compatible with standard organic solvents for synthesis and analysis
Medchemexpress LLC Coumarin hydrazine | 113707-87-2 | MFCD09999551 | 97.1% | 190.20 g/mol | C10H10N2O2 | 50MG
Coumarin hydrazine is an aromatic hydrazine-containing coumarin fluorophore used as a chemical probe to label protein- and lipid-bound carbonyls in cells. It excites in the 420-450 nm range and emits near 468-490 nm, and is provided as a solid reagent for research applications.
Medchemexpress LLC 4-Methoxycoumarin | 20280-81-3 | 176.17 g/mol | C10H8O3 | 1 G
4-Methoxycoumarin is a coumarin derivative used in research with reported antibacterial activity against Ralstonia solanacearum. It is supplied as a powder with chemical formula C10H8O3 (molecular weight 176.17 g/mol) and CAS number 20280-81-3. The compound is soluble in DMSO (100 mg/mL; ultrasonic assistance recommended), and storage guidance and solution stability are provided for laboratory handling.
- Antibacterial activity against Ralstonia solanacearum
- Chemical formula C10H8O3 and molecular weight 176.17 g/mol
- CAS number 20280-81-3 for unambiguous identification
- High DMSO solubility: 100 mg/mL (requires ultrasonic)
- Storage stability: powder -20°C (up to 3 years), 4°C (up to 2 years); in solvent -80°C (6 months), -20°C (1 month)
- Solution preparation guidance from 1 g: 1 mM = 5.6763 mL, 5 mM = 1.1353 mL, 10 mM = 0.5676 mL
Cayman Chemical 7-AmIno-4-methylcoumarIn 500mg
A fluorescent probe for peptide labeling commonly used in the study of proteases; conjugation via its amino group to a peptide substrate results in quenching of the fluorescent signal; upon enzymatic cleavage of the peptide by proteases, AMC is released and its fluorescence can be used to quantify enzyme activity; ex/em = 345/445 nm, respectively