Coumarins and derivatives
Medchemexpress LLC 2h-1-benzopyran-2-one, 7-ethoxy-4-methyl- | 87-05-8 | MFCD00016971 | 99.4% | 25 G
7-Ethoxy-4-methylcoumarin is a coumarin derivative that serves as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6. It is intended for research use only and not for sale to patients.
- Coumarin derivative.
- Functions as a substrate probe for specific cytochrome P450 enzymes.
- Useful in research and analytical applications.
- Targets CYP1A1, CYP2B4, and CYP2B6.
- Can be classified as a fluorescent dye.
- Used in labeling chemistry.
- A metabolic enzyme/protease.
Medchemexpress LLC 7-Hydroxycoumarin-4-acetic acid | 6950-82-9 | 250 MG
7-Hydroxycoumarin-4-acetic acid is a pH-indicator dye that is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm). This product is intended for research use only.
- pH-indicator dye
- Covalently bound to bovine serum albumin (BSA)
- White to off-white solid
- Molecular weight 220.18
- Chemical formula C11H8O5
- Emission (Em): 450
- Excitation (Ex): 415
- Store at 4°C, protect from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protect from light
Medchemexpress LLC 6-Methylcoumarin | 92-48-8 | 160.17 | 1 G
6-Methylcoumarin is a synthetic fragrance widely used in cosmetics. It is reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models and is for research use only. Store powder at -20°C for 3 years or 4°C for 2 years. When in solvent, store at -80°C for 2 years or -20°C for 1 year.
- Purity: 99.98%
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC 6-Methylcoumarin | 92-48-8 | 160.17 | 1 ML
6-Methylcoumarin is a synthetic fragrance primarily used in cosmetics. It has been reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models. Studies show that when HaCaT cells are treated with 6-Methylcoumarin and UVA irradiation, it produces γ-H2AX-positive cells at concentrations from 100 nM.
- Synthetic fragrance widely used in cosmetics.
- Reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models.
Medchemexpress LLC Coumarin | 91-64-5 | MFCD00006850 | 146.15 | 1 G
Coumarin is a potent and orally active anti-inflammatory agent. It also shows an antinociceptive effect, and antibacterial, antifungal, and anticancer activity.
- Potent and orally active anti-inflammatory agent
- Shows antinociceptive effect
- Exhibits antibacterial, antifungal, and anticancer activity
Medchemexpress LLC Coumarin (Standard) | 91-64-5 | 146.14 | 100 MG
Coumarin (Standard) is the analytical standard of Coumarin, intended for research and analytical applications. It is a potent, orally active anti-inflammatory agent, also exhibiting antinociceptive, antibacterial, antifungal, and anticancer activities.
This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Intended for research and analytical applications.
- Functions as an anti-inflammatory agent.
- Exhibits antinociceptive effects.
- Shows antibacterial activity.
- Displays antifungal activity.
- Demonstrates anticancer activity.
- Suitable for HPLC, GC, and MS research.
Medchemexpress LLC Coumarin | 91-64-5 | 146.15 | 5 G
Coumarin is a potent and orally active anti-inflammatory agent. It also demonstrates antinociceptive, antibacterial, antifungal, and anticancer activities.
- Potent and orally active anti-inflammatory agent
- Shows antinociceptive effect
- Shows antibacterial, antifungal and anticancer activity
Medchemexpress LLC Coumarin | 91-64-5 | 146.15 | 500 MG
Coumarin is a potent and orally active anti-inflammatory agent. It demonstrates an antinociceptive effect, as well as antibacterial, antifungal, and anticancer activities.
- Potent and orally active anti-inflammatory agent.
- Shows an antinociceptive effect.
- Exhibits antibacterial activity.
- Exhibits antifungal activity.
- Exhibits anticancer activity.
Medchemexpress LLC Coumarin-d4 | 185056-83-1 | 150.17 | 5 MG
Coumarin-d4 is the deuterium labeled version of Coumarin, which is the primary bioactive ingredient found in Radix Glehniae, also known as Beishashen in China. It exhibits various pharmacological activities, including anticancer, anti-inflammation, and antiviral properties. Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs. It is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | MFCD00006880 | 5 G
7-Methylcoumarin is a coumarin derivative known for its potent hepatoprotective and antioxidant properties. It functions as a mechanism-based inhibitor for CYP2A6, a key enzyme involved in drug metabolism. Studies have shown that it can significantly reduce markers of liver damage, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB), in models of CCl4-induced liver injury. Additionally, it helps to restore total protein (TP) and albumin (TA) levels and prevent oxidative stress. It also exhibits an ability to decrease the mitotic activity of *A. sativum* promeristem.
- Possesses potent hepatoprotective properties
- Acts as a mechanism-based inhibitor for CYP2A6
- Reduces markers of liver damage
- Restores protein and albumin levels in serum
- Prevents oxidative stress
- Decreases mitotic activity
Medchemexpress LLC Coumarin 6 | 38215-36-0 | 1 ML
Coumarin 6 is a fluorescent dye utilized as a fluorescent probe within microparticle drug delivery systems. It is employed to conduct in vivo tracking, cellular uptake studies, and investigations into the transport mechanisms of drug delivery systems. It has an excitation wavelength (λexc) of 450 nm and an emission wavelength (λem) of 505 nm. This product is intended for research use only and is not sold to patients.
- Used for in vivo tracking, cell uptake, and transport mechanism studies in drug delivery systems
- Optimal wavelengths: Excitation at 450 nm and emission at 505 nm
- Purity: 99.59%
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | MFCD00630040 | 500 MG
6-Hydroxycoumarin is a coumarin that exhibits a range of biological activities. It is intended for research use only.
- Anti-inflammatory properties
- Anti-pyretic properties
- Anti-oxidant properties
- Vasodilator properties
- Anti-amoebic properties
- Anti-bacterial properties
- Anti-fungal properties
- Bacteriostatic properties
- Antitumor properties
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | MFCD00006856 | 10MM 1ML
4-Hydroxycoumarin | 1076-38-6 | MFCD00006856 | 10MM 1ML
Medchemexpress LLC 4-Hydroxycoumarin (standard) | 1076-38-6 | 50 MG
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin, intended for research and analytical applications. It is an orally active coumarin derivative and a versatile heterocyclic scaffold, frequently used in the synthesis of diverse organic compounds. The product exhibits both electrophilic and nucleophilic properties.
- Analytical standard.
- Intended for research and analytical applications.
- Orally active coumarin derivative.
- Versatile heterocyclic scaffold.
- Used in the synthesis of various organic compounds.
- Possesses both electrophilic and nucleophilic properties.
- Functions as an HIV protease inhibitor.
- Functions as a tyrosine kinase inhibitor.
- Displays anti-inflammatory effects.
- Displays antibacterial effects.
- Displays anti-tumor effects.
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 50 G
4-Hydroxycoumarin is an orally active coumarin derivative, a versatile heterocyclic scaffold used in synthesizing various organic compounds. It possesses both electrophilic and nucleophilic properties. It acts as an HIV protease inhibitor and tyrosine kinase inhibitor, and exhibits anti-inflammatory, antibacterial, and anti-tumor effects.
- Orally active coumarin derivative
- Versatile heterocyclic scaffold for organic compound synthesis
- Possesses both electrophilic and nucleophilic properties
- Acts as an HIV protease inhibitor
- Acts as a tyrosine kinase inhibitor
- Exhibits anti-inflammatory effects
- Exhibits antibacterial effects
- Exhibits anti-tumor effects