Coumarins and derivatives
Medchemexpress LLC 3-Acetylcoumarin | 3949-36-8 | 97.0% | 188.18 | 5 G
3-Acetylcoumarin (Compound 4) exhibits acaricidal activity against *Tetranychus cinnabarinus* and is intended for research use only. It has shown biological activity in various assays.
- Exhibits acaricidal activity against *Tetranychus cinnabarinus*
- IC50 of 14.45 μM for inhibition of human recombinant MAO-B
- IC50 of 75 μM for cytotoxicity against human SH-SY5Y cells
eMolecules 90349-18-1 | 4-(Ethylamino)-3-nitrobenzonitrile | MFCD00186035 | 1g
Combi-Blocks | 4-(Ethylamino)-3-nitrobenzonitrile | 1g | 205380622 | AN-1541 | 96.000 | 90349-18-1 | MFCD00186035 | 191.190 | C9H9N3O2
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Selleck Chemical LLC Dicoumarol S4299-200mg
Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor and used as an anticoagulant by interfering with the metabolism of vitamin K
Cayman Chemical 4-HydroxycoumarIn 250g
A coumarin; inhibits vitamin K1 epoxidation and prothrombin synthesis by 18 and 67%, respectively, in cell-free assays at 6.2 mM; has been used in the synthesis of anticoagulants, as well as antithrombotic, anti-inflammatory, antibacterial, and antifungal agents
Medchemexpress LLC 7-Hydroxycoumarin-4-acetic acid | 6950-82-9 | MFCD00037563 | 5 G
7-Hydroxycoumarin-4-acetic acid is a pH-indicator dye that covalently binds to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm). It is for research use only.
- Molecular weight: 220.18
- Formula: C11H8O5
- Appearance: Solid
- Color: White to off-white
- Emission (Em): 450
- Excitation (Ex): 415
Medchemexpress LLC 2H-1-Benzopyran-2-one, 7-ethoxy-4-methyl- | 87-05-8 | MFCD00016971 | 99.4% | 10 G
7-Ethoxy-4-methylcoumarin is a coumarin derivative that can be used as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6. It is for research use only.
- Coumarin derivative
- Substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6
- Solid appearance
- White to off-white color
![Medchemexpress LLC 6H-dibenzo[b,d]pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]- | 914913-88-5 | MFCD18633224 | 99.3% | C24H22O6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261568.png-250.jpg)
Medchemexpress LLC 6H-dibenzo[b,d]pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]- | 914913-88-5 | MFCD18633224 | 99.3% | C24H22O6 | 10MG
Palomid 529 is a small-molecule research inhibitor that targets both mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2), modulating the PI3K/Akt/mTOR signaling pathway. It has been used in preclinical studies and early clinical research to reduce tumor growth, angiogenesis, and vascular permeability, and has been investigated for neovascular age-related macular degeneration.
- Dual inhibition of mTORC1 and mTORC2.
- Documented in peer-reviewed literature and public chemical databases.
- High reported purity suitable for analytical use.
- Suitable as an analytical standard and research reagent.
- Provided with batch-specific certificate of analysis data.
Medchemexpress LLC 7-Methoxycoumarin-3-carboxylic acid, SE | 150321-92-9 | 317.25 | 100 MG
7-Methoxycoumarin-3-carboxylic acid, SE can be used for the synthesis of hydrophilic dye compound 12. Compound 12 shows a homogeneous distribution inside the cell and represents a suitable probe for viscosity measurements in the cytoplasm. This product is for research purposes only and not for sale to patients.
- Used for the synthesis of hydrophilic dye compound 12
- Suitable probe for viscosity measurements in the cytoplasm
Cayman Chemical 7-AmIno-4-methylcoumarIn 1g
A fluorescent probe for peptide labeling commonly used in the study of proteases; conjugation via its amino group to a peptide substrate results in quenching of the fluorescent signal; upon enzymatic cleavage of the peptide by proteases, AMC is released and its fluorescence can be used to quantify enzyme activity; ex/em = 345/445 nm, respectively
Medchemexpress LLC 4-Ethoxycoumarin | 35817-27-7 | 99.93% | 190.20 | 5 G
4-Ethoxycoumarin is an antimicrobial compound used for research purposes. It has a molecular weight of 190.20 and a purity of 99.93%. The compound should be stored at room temperature for up to 3 years. When in solvent, it can be stored at -80°C for 2 years or -20°C for 1 year. For shipping, it can be transported at room temperature if the duration is less than 2 weeks. Keep the container tightly sealed in a cool, well-ventilated area, away from direct sunlight and sources of ignition.
- Antimicrobial properties
- High purity of 99.93%
- Stable for 3 years at room temperature
- Stable for 2 years at -80°C in solvent
- Stable for 1 year at -20°C in solvent
- Suitable for research use
Sigma Aldrich Fine Chemicals Biosciences 2-(Ethylamino)ethanol >=98% | 110-73-6 | MFCD00002841 | 500ML
2-(Ethylamino)ethanol >=98% | Purity: >=98% | Mol Wt: 89.14 | 110-73-6 | MFCD00002841 | 500ML
Medchemexpress LLC 7-Methoxy-4-methyl-coumarin-8-ol | 22084-94-2 | 206.19 | 5 MG
7-Methoxy-4-methyl-coumarin-8-ol is a compound isolated from sour orange (Citrus aurantium). It is for research use only and not sold to patients. This product appears as a white to off-white solid and boasts a purity of 99.92%.
- Isolated from sour orange (Citrus aurantium)
- High purity of 99.92%
- Appears as a white to off-white solid
- For research use only
- Ships at room temperature in continental US
- Store at 4°C, sealed, away from moisture and light
- Soluble in DMSO for in vitro applications
- Soluble in 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline for in vivo applications
Medchemexpress LLC AZP-531 | 1088543-62-7 | 99.8% | 962.02 | 10 MG
AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. It exerts survival effects on pancreatic b-cells and human pancreatic islets comparable to unacylated ghrelin (UAG). It is very stable in human plasma in vitro with no degradation observed after 1 day of incubation at 37°C.
- Prevents body weight increase caused by a high-fat diet in mice
- Prevents high-fat diet-induced proinflammatory effects
- Stimulates mitochondrial function markers in brown adipose tissue
- Prevents the development of a prediabetic metabolic state
- Prevents a high-fat diet-induced increase in acyl ghrelin levels
- Significantly improves glucose concentrations without increasing insulin levels
- Decreases mean body weight by 2.6 kg (vs 0.8 kg for placebo)
- Reduces HbA1c by 0.4% (vs 0.2% for placebo)
Medchemexpress LLC Coumarin-3-carboxylic acid | 531-81-7 | MFCD00006852 | 99.9% | 190.15 g/mol | C10H6O4 | 25 G
Coumarin-3-carboxylic acid is a small-molecule fluorescent probe (C10H6O4, MW 190.15 g/mol) used to detect hydroxyl radicals and study oxidative stress in analytical and biochemical research. It is provided in high-purity solid form and as a DMSO solution for convenient use in assays and photophysical measurements.
- High purity suitable for analytical and preparative work.
- Strong fluorescence signal for sensitive radical detection.
- Available in multiple package sizes and solution format.
- Documented spectral and chromatographic data for quality assurance.
- Applicable to in vitro assays and photophysical studies.
Medchemexpress LLC Coumarin 314 | 55804-66-5 | MFCD00051334 | 98.0% | 313.35 g·mol⁻¹ | C18H19NO4 | 100 MG
Coumarin 314 is a fluorescent dye exhibiting strong absorption in the visible region and pronounced solvent-dependent spectral properties. It is supplied as a light yellow solid and is used primarily as a research reagent in fluorescence measurements, probe design, and photophysical studies.
- Strong visible absorption and fluorescence.
- Pronounced solvent-dependent spectral behavior.
- High purity for research applications.
- Light yellow solid appearance for easy handling and identification.
- Suitable for photophysical and fluorescence probe studies.