Depsides and depsidones
Medchemexpress LLC Alogliptin Benzoate (SYR 322) | 850649-62-6 | 100.0% | C25H27N5O4 | 200 MG
Alogliptin Benzoate (SYR-322) is a potent, selective, and orally active inhibitor of DPP-4 with an IC50 of <10 nM, exhibiting over 10,000-fold selectivity over DPP-8 and DPP-9. It is suitable for research into type 2 diabetes.
- Potent, selective, and orally active inhibitor of DPP-4.
- Inhibits LPS-induced extracellular signal-regulated kinase (ERK) phosphorylation in U937 cells.
- Inhibits LPS-stimulated MMP-1 secretion and mRNA expression mediated by the ERK pathway in U937 cells.
- Improves glucose tolerance and increases plasma insulin levels in female Wistar fatty rats.
- Reduces infarction area and improves brain vascular integrity in middle cerebral artery occlusion (MCAO) mice.
Cayman Chemical MetronIdazole Benzoate 250mg
An antibiotic and antiprotozoal agent; active against P. asaccharolyticus, C. perfringens, C. septicum, B. fragilis, and B. thetaiotaomicron (MICs = 3.6, 7.3, 1.8, 7.3, and 7.3 µM, respectively); reduces parasitemia in rats when cultured with T. congolense or T. brucei prior to infection
Cayman Chemical EUK 118 Neurochemicals
A synthetic catalytic scavenger of reactive oxygen species, with reduced activity compared to EUK 8 and EUK 134
Medchemexpress LLC Fotagliptin benzoate | 1403496-40-1 | 99.2% | 464.49 g·mol⁻1 | C24H25FN6O3 | 5MG
Fotagliptin benzoate is a research-grade dipeptidyl peptidase-4 (DPP-4) inhibitor provided as the benzoate salt for preclinical and biochemical studies related to type 2 diabetes research. It is supplied as a solid powder and in small analytical vial sizes for laboratory use.
Medchemexpress LLC Alogliptin Benzoate (Standard) | 850649-62-6 | 99.3% | C25H27N5O4 | 5 MG
Alogliptin Benzoate (Standard) is an analytical standard of Alogliptin (Benzoate) for research and analytical applications. It is a potent, selective, and orally active inhibitor of DPP-4 with an IC50 of <10 nM, exhibiting over 10,000-fold selectivity over DPP-8 and DPP-9. This analytical standard is suitable for type 2 diabetes research and commonly employed in qualitative, quantitative, and methodological research experiments using techniques like HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Potent, selective, and orally active DPP-4 inhibitor
- IC50 of <10 nM
- Exhibits over 10,000-fold selectivity over DPP-8 and DPP-9
- Suitable for type 2 diabetes research
- Used in qualitative, quantitative, and methodological research experiments
- Compatible with HPLC, GC, and MS techniques
Medchemexpress LLC Alogliptin (Benzoate) | 850649-62-6 | 99.98% | C25H27N5O4 | 1 ML
Alogliptin Benzoate (SYR-322) is a potent, selective, and orally active inhibitor of DPP-4, primarily used for research related to type 2 diabetes. It exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
- Potent and selective DPP-4 inhibitor
- Orally active
- Used for type 2 diabetes research
- Inhibits LPS-induced ERK phosphorylation in U937 cells
- Reduces infarction area and improves brain vascular integrity in MCAO mice
Medchemexpress LLC Ammonium benzoate | 1863-63-4 | 100g
Ammonium benzoate is the ammonium salt of benzoic acid which is used as a preservative in some adhesives and rubber emulsions and is also a commonly used chemical synthesis intermediate
Medchemexpress LLC n-Butyl benzoate | 136-60-7 | MFCD00009439 | 99.7% | 178.23 g·mol⁻¹ | C11H14O2 | 1 KG
Butyl benzoate (n-butyl benzoate) is an aromatic ester used as a solvent, fragrance ingredient, and chemical intermediate. It is supplied as a clear, high-purity liquid suitable for research, formulation, and analytical applications.
- High purity (99.73%) liquid for research and formulation use.
- Used as a solvent and perfume ingredient in fragrance and flavor applications.
- Low volatility and good solvency for aromatic compounds.
- Soluble in common organic solvents and DMSO for analytical preparations.
- Available in multiple pack sizes for lab-scale use.
Cayman Chemical Methyl SalIcylate-d4 10mg
An internal standard for the quantification of methyl salicylate by GC- or LC-MS
Medchemexpress LLC Fotagliptin benzoate | 1403496-40-1 | 99.2% | 464.49 | C24H25FN6O3 | 25MG
Fotagliptin benzoate is a Dipeptidyl Peptidase-4 (DPP-4) inhibitor provided as a benzoate salt for research use. It is intended for studies of type 2 diabetes mellitus and is supplied in analytical/research grade formulations with reported high purity and available package sizes suitable for both in vitro and in vivo experiments.
- Dipeptidyl peptidase-4 (DPP-4) inhibitor (IC50 = 2.27 nM).
- High purity (99.2%).
- Molecular weight 464.49 g/mol.
- Molecular formula C24H25FN6O3.
- Available in multiple package sizes, including 25 mg.
- Suitable for in vitro and in vivo studies.
- Reported safety data available from rat and dog studies.
Apexbio Technology LLC Denatonium benzoate 3734-33-6 200mg
Denatonium benzoate is a small-molecule agonist targeting bitter taste receptors (TAS2Rs) It is designed to activate TAS2Rs thereby initiating intracellular signaling cascades involved in metabolic regulation and immune response Denatonium benzoate exerts its biological activity primarily through binding and activating TAS2Rs expressed on multiple cell populations In laboratory studies Denatonium benzoate demonstrates receptor activation contributing to investigations of taste receptor activation and insulin secretion Based on these pharmacological properties Denatonium benzoate holds research potential in elucidating glucose homeostasis metabolic functions immune cell activation and the role of bitter taste signaling in immunity and allergic responses