Flavonoids
Medchemexpress LLC Psb-sb-487 | 1399049-81-0 | 98.0% | 408.53 g/mol | C26H32O4 | 50MG
PSB-SB-487 is a small-molecule research compound that functions as a potent GPR55 antagonist and a CB2 receptor agonist. It is supplied as a white to off-white solid for laboratory use and is intended for research use only. The compound has CAS number 1399049-81-0 and a molecular weight of 408.53 g/mol.
- Potent GPR55 antagonist and CB2 agonist.
- High purity (approximately 98.0%).
- Molecular formula C26H32O4; molecular weight 408.53 g/mol.
- Supplied as a white to off-white solid.
- Soluble in DMSO at high concentration (100 mg/mL; ultrasonic recommended).
- Recommended storage conditions for powder and solutions to maintain stability.
- For research use only; not for human or diagnostic use.
Apexbio Technology LLC AST 487 630124-46-8 10mg
AST487 (CAS 630124-46-8) is a small molecule inhibitor primarily targeting RET kinase exhibiting an IC50 of 0 88 M As a member of the N N -diphenylurea class AST487 inhibits RET autophosphorylation and attenuates downstream signaling pathways such as PLC and ERK in a dose-dependent manner It also displays inhibitory activity against additional kinases including KDR Flt-3 and c-Kit In cellular models harboring RET activating mutations (e g C634W) AST487 suppresses RET-mediated signaling and reduces proliferation of thyroid carcinoma cells with RET mutations In xenograft mouse models oral administration of AST487 leads to a notable reduction in tumor volume making it valuable for preclinical studies of RET-driven cancers
TARGETMOL CHEMICALS INC HARMOL 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Harmol (Methylpyridoindolol) is a (beta)-carboline isolated from nature. purity: 98%
Medchemexpress LLC 7,8-Dihydroxyflavone | 38183-03-8 | 254.24 | 25 MG
7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). It displays therapeutic efficacy toward various neurological diseases.
- Protects primary cortical neurons and locus coeruleus neurons from Aβ-induced toxicity
- Promotes dendritic growth and synaptogenesis
- Prevents synaptic loss and memory deficits in an Alzheimer's Disease model
- Activates TrkB in the brain
- Inhibits kainic acid-induced toxicity
- Decreases infarct volumes in stroke
- Neuroprotective in a Parkinson disease model
Medchemexpress LLC 3,6-Dihydroxyflavone | 108238-41-1 | 25 MG
3,6-Dihydroxyflavone is an anti-cancer agent that decreases cell viability and induces apoptosis. It works by activating the caspase cascade and cleaving poly (ADP-ribose) polymerase (PARP). Additionally, it increases intracellular oxidative stress and lipid peroxidation.
- Decreases cell viability and induces apoptosis
- Activates caspase cascade
- Cleaves poly (ADP-ribose) polymerase (PARP)
- Increases intracellular oxidative stress
- Increases lipid peroxidation
- Appears as a light yellow to light brown solid
- Has a molecular weight of 254.24
- Chemical formula is C15H10O4
- Purity is 98.06%
- Soluble in DMSO at 66.67 mg/mL
Cayman Chemical HesperIdIn methylchalconC 50g
A C. aurantium extract that contains hesperidin methylchalcone, among other compounds
Sigma Aldrich Fine Chemicals Biosciences 3',4'-Dimethoxyflavone | 4143-62-8 | MFCD00143009 | 25MG
3',4'-Dimethoxyflavone | Purity: >=98% (HPLC) | Mol Wt: 282.29 | 4143-62-8 | MFCD00143009 | 25MG
TARGETMOL CHEMICALS INC Acacetin 50MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, exhibiting antinociceptive, anti-inflammatory, and antioxidant activities in different research models. Purity 98%
Medchemexpress LLC 5,7-Dimethoxyflavone | 21392-57-4 | 50 MG
5,7-Dimethoxyflavone is an analytical standard and a major component of Kaempferia parviflora. It exhibits anti-obesity, anti-inflammatory, and antineoplastic effects. This product is intended for research and analytical applications.
- Inhibits cytochrome P450 (CYP) 3As
- Potent breast cancer resistance protein (BCRP) inhibitor
- Used for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Shipping is at room temperature in continental US; may vary elsewhere. Store under recommended conditions in the Certificate of Analysis.
Medchemexpress LLC Hesperidin methylchalcone | 1 g | | HY-126382-1g | 24292-52-2 | MW: 624.59
Hesperidin methylchalcone (Hesperidin methyl chalcone) is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone can be used for the research of gout disease.
Medchemexpress LLC Acacetin (5,7-dihydroxy-4'-methoxyflavone) | 480-44-4 | MFCD00016936 | 99.7% | 284.26 | C16H12O5 | 10 MG
Acacetin (5,7-dihydroxy-4'-methoxyflavone) is an O-methylated flavone used as a research reagent for studies of apoptosis, autophagy, and inflammatory signaling. It is supplied as a high-purity reference material for in vitro and preclinical experiments.
- CAS number: 480-44-4.
- Molecular formula: C16H12O5.
- Molecular weight: 284.26 g/mol.
- Purity: 99.7%.
- Available pack sizes: 1 mg-1 g for laboratory use.
- Documentation provided: data sheet, certificate of analysis, and safety data sheet.
Sigma Aldrich Fine Chemicals Biosciences 3',4'-Dimethoxyflavone | 4143-62-8 | MFCD00143009 | 5MG
3',4'-Dimethoxyflavone | Purity: >=98% (HPLC) | Mol Wt: 282.29 | 4143-62-8 | MFCD00143009 | 5MG
Cayman Chemical rac-HesperetIn-d3 1mg
An internal standard for the quantification of hesperetin by GC- or LC-MS
Medchemexpress LLC 5,7-Dimethoxyflavone | 21392-57-4 | 1 ML
5,7-Dimethoxyflavone is a major component of *Kaempferia parviflora* with diverse biological activities. It exhibits anti-obesity, anti-inflammatory, and antineoplastic effects. This compound acts as an inhibitor of cytochrome P450 (CYP) 3As and is a potent Breast Cancer Resistance Protein (BCRP) inhibitor.
- Exhibits anti-obesity, anti-inflammatory, and antineoplastic effects
- Acts as a potent inhibitor of CYP3A and BCRP
- Inhibits Bcrp1-mediated Sorafenib efflux
- Induces melanogenesis
- Inhibits lipid accumulation and adipocyte differentiation
- Reduces liver CYP3A11 and CYP3A25 protein expression
- Inhibits sarcopenia
- Decreases body weight gain and inhibits fatty liver
Sigma Aldrich Fine Chemicals Biosciences 57-Dimethoxyflavone phypro25MG
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity water residual solvents inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH Co. KG