Flavonoids
Apexbio Technology LLC 7,8-Dihydroxyflavone 38183-03-8 10mg
7 8-Dihydroxyflavone (CAS 38183-03-8) is a small-molecule compound that acts as a selective agonist of the tropomyosin receptor kinase B (TrkB) By mimicking the action of brain-derived neurotrophic factor (BDNF) it activates TrkB-mediated signaling pathways resulting in enhanced neuronal survival and modulation of synaptic plasticity 7 8-Dihydroxyflavone is widely utilized in experimental studies on neurodegenerative diseases and neurological disorders serving as a valuable tool for investigating neurotrophic signaling mechanisms and the development of potential therapeutics for central nervous system pathologies
Medchemexpress LLC Apigenin 7-O-malonylglucoside | 86546-87-4 | 1 MG
Apigenin 7-O-malonylglucoside is a flavonoid found in chrysanthemum flowers. It is for research use only.
- Purity >98%
- Appearance: solid
- Color: white to off-white
- Molecular weight: 518.42
- Chemical formula: C24H22O13
- Storage: 4°C, protect from light
- Storage in solvent: -80°C, protect from light
- Soluble in DMSO
Medchemexpress LLC 7,8-Dihydroxyflavone | 38183-03-8 | 254.24 | 25 MG
7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). It displays therapeutic efficacy toward various neurological diseases.
- Protects primary cortical neurons and locus coeruleus neurons from Aβ-induced toxicity
- Promotes dendritic growth and synaptogenesis
- Prevents synaptic loss and memory deficits in an Alzheimer's Disease model
- Activates TrkB in the brain
- Inhibits kainic acid-induced toxicity
- Decreases infarct volumes in stroke
- Neuroprotective in a Parkinson disease model
Apexbio Technology LLC Catechin 154-23-4 10mg
Catechin (154-23-4) is a small-molecule inhibitor targeting cyclooxygenase-1 (COX-1) It is designed to inhibit COX-1 activity thereby modulating inflammation-related pathways Catechin exerts its biological activity primarily through inhibition of COX-1 In cell-based assays catechin demonstrates inhibitory activity with an IC50 value of approximately 1 4 M Based on these pharmacological properties catechin holds research potential in studies of oxidative stress pathways inflammation processes and enzyme inhibition screening
Cayman Chemical ApIgenIn 7-glucosIde 25mg
A flavonoid with anti-inflammatory and anxiolytic activities; inhibits LPS-induced nitric oxide production in RAW 264.7 cells from 0.16-10 μM; reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury at 10 mg/kg; increases the number of entries and the time spent in the open arms of the elevated plus maze in rats
TARGETMOL CHEMICALS INC Gallocatechin gallate 25MG
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. (-)-Gallocatechin gallate ((-)-gallocatechin-3-O-gallate) is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM. Purity 99.78%
TARGETMOL CHEMICALS INC Catechin Hydrate 1G
Also available in 1 mL, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. (+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems. Purity 99.03%
TARGETMOL CHEMICALS INC 4-Hydroxyflavone 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 4'-Hydroxyflavone is a flavonoid compound isolated from the roots of Scutellaria baicalensis with anti-inflammatory activity. Purity 99.42%
Selleck Chemical LLC Rutin hydrate
Rutin (Quercetin-3-O-rutinoside Rutoside Sophorin) is a glycoside found in a wide variety of plants including citrus fruit
Selleck Chemical LLC 7 8-Dihydroxyflavone
7 8-Dihydroxyflavone (7 8-DHF) acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd 320 nM) the main signaling receptor of brain-derived neurotrophic factor (BDNF)