Flavonoids
Sigma Aldrich 5-Methyl-1,10-phenanthroline
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
TARGETMOL CHEMICALS INC Epigallocatechin-3-3-O-methyl
Also available in 1 mL, 5 mg, 10 mg, 25 mg and bulk. Please contact Fisher for quotes. (-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product isolated from tea leaves with potent antioxidant, cytotoxic, and antibacterial properties, and it improves the adhesive stability of etching rinsing adhesives to dentin. Purity 99.59%
Cayman Chemical EpIgalocatechIn Galate 50mg
A phenol with diverse biological activities; lytic against T. cruzi amastigotes (MBC50 = 0.53 pM); decreases deoxyguanosine oxidation and tyrosine nitration (IC50s = 0.25 and 0.11 mM, respectively) and inhibits macrophage-mediated LDL oxidation in vitro; inhibits heregulin-β1-induced activation of ErbB2 and ErbB3, as well as migration and invasion of MCF-7 breast cancer cells; reduces food intake and body weight, serum levels of insulin, leptin, testosterone, and growth hormone, and the size of the ventral prostate, testis, liver, and spleen in male Sprague Dawley, lean Zucker and obese Zucker rats at 82, 81, and 92 mg/kg, respectively; reduces increases in hepatic steatosis, inflammatory cell infiltration, and injury in a mouse model of methionine- and choline-deficient diet-induced NASH at 50 and 100 mg/kg
TARGETMOL CHEMICALS INC Neohesperidin 500MG
Also available in 1 g, 5 g, 1 mL, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model. Purity 98.34%
Medchemexpress LLC HY-N0014 100mg Medchemexpress, Icariin CAS:489-32-7 Purity:>98%
Medchemexpress, HY-N0014 100mg Icariin CAS:489-32-7 Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC 50 s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC 7,8-Dihydroxyflavone 38183-03-8 50mg
7 8-Dihydroxyflavone (CAS 38183-03-8) is a small-molecule compound that acts as a selective agonist of the tropomyosin receptor kinase B (TrkB) By mimicking the action of brain-derived neurotrophic factor (BDNF) it activates TrkB-mediated signaling pathways resulting in enhanced neuronal survival and modulation of synaptic plasticity 7 8-Dihydroxyflavone is widely utilized in experimental studies on neurodegenerative diseases and neurological disorders serving as a valuable tool for investigating neurotrophic signaling mechanisms and the development of potential therapeutics for central nervous system pathologies
Apexbio Technology LLC Troxerutin 7085-55-4 5g
Troxerutin (CAS 7085-55-4) is a bioactive small molecule known to exhibit protective effects against gamma radiation (GR)-induced DNA damage It promotes DNA repair mechanisms thereby reducing radiation-related single- and double-strand breaks Experimentally Troxerutin (1 mM) decreased GR-triggered micronucleus formation in human lymphocytes by approximately 41% In mouse models intraperitoneal administration before or after irradiation (up to 175 mg/kg) minimized micronucleus frequency in reticulocytes and mitigated DNA strand breaks in leukocytes and bone marrow cells with dosage-dependent results Its properties make Troxerutin relevant for radiation biology research particularly in genomic stability and radioprotection studies
Selleck Chemical LLC Nicotiflorin (Kaempferol-3-O-rutinoside) S3267-5mg
Nicotiflorin (Kaempferol-3-O-rutinoside) a flavonoid extracted from Carthamus tinctorius alters the shape and structure of injured neurons decreases the number of apoptotic cells down-regulates expression of p-JAK2 p-STAT3 caspase-3 and Bax and decreases Bax immunoredactivity and increases Bcl-2 protein expression and immunoreactivity
Selleck Chemical LLC Acacetin S5318-1g
Acacetin (Linarigenin 5 7-dihydroxy-4 -methoxyflavone 4 -Methoxyapigenin) is a flavonoid compound that has been shown to have anti-cancer anti-mutagenic anti-inflammatory and anti-peroxidative effects
AdipoGen Catechin
Chemical. CAS 18829-70-4. Formula C15H14O6. MW 290.27. Catechins have wide biological functionality, including antioxidant, anti-inflammatory, antiviral and anticancer activities. Catechins also play a key role in regulating carbohydrate and lipid metabolism. --Catechin is comparatively less bioavailable than the stereoisomer -catechin for intestinal absorption. It shows antioxidant free radical scavenging and antidiabetic activities. --Catechin has been shown to be a stereoselective PPARgamma agonist. It activates PPARgamma in a dose-dependent fashion, promotes adipocyte differentiation and increases sensitivity to insulin. It markedly suppresses the expression of Kruppel-like factor 7 KLF7 protein, which has recently been reported to inhibit the expression of adiponectin and other adipogenesis related genes, including leptin, PPARgamma, C/EBPalpha, and aP2 in adipocytes. It also has shown to have anti-reverse transcriptase activity and maltase inhibitory activity.
Indofine Chemical Myricetin With Hplc, 10 Mg
MYRICETIN with HPLC 10 MG, Flavone, 3,5,7,3',4',5'-Hexahydroxyflavone, Cannabiscetin, C15H10O8, MW: 318.25, 99% by HPLC, 529-44-2, MFCD00006827
Medchemexpress LLC 3'-hydroxyflavanone | 92496-65-6 | MFCD00017738 | >98.0% | 240.25 g/mol | C15H12O3 | 1 G
3'-Hydroxyflavanone is a cyclized flavanone (C15H12O3) reported to induce apoptosis in HeLa cells and to possess antitumor activity in cellular studies. It is employed in biochemical and pharmacological research to probe apoptosis pathways and to study flavonoid bioactivity.
- Cyclized flavanone scaffold with a 3'-hydroxy substitution.
- Reported to induce apoptosis in HeLa cells.
- Demonstrated antitumor activity in preclinical cellular studies.
- Useful as a biochemical probe for apoptosis-related pathways.
- Supplied as a solid with defined molecular formula and molecular weight.