Benzene and substituted derivatives
Selleck Chemical LLC AG 555
AG-555 (Tyrphostin B46) is an inhibitor of tyrosine kinase interacts directly with topoisomerase I thus preventing DNA relaxation It inhibits EGFR with an IC50 of 0 7 M
AdipoGen Rifamycin AG
Chemical. CAS 38128-51-7. Formula C38H49N5O11. MW 751.8. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase RNAP. Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex MAC infections.
AdipoGen Rifamycin AG
Chemical. CAS 38128-51-7. Formula C38H49N5O11. MW 751.8. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase RNAP. Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex MAC infections.
Selleck Chemical LLC AG-126
AG126 is a tyrosine kinase inhibitor which selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 M
TARGETMOL CHEMICALS INC AG-636 5MG
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. AG-636 is a potent, reversible, and selective DHODH inhibitor with an IC50 of 17 nM and is orally active. It demonstrates strong anticancer effects. Purity 99.19%
Medchemexpress LLC AG 555 (Tyrphostin AG 555) | 133550-34-2 | C19H18N2O3 | 1 ML
AG 555 (Tyrphostin AG 555) is a potent antiretroviral agent that acts as a selective inhibitor of EGFR and blocks Cdk2 activation. This product is for research use only.
- Potent antiretroviral agent
- Selective inhibitor of EGFR
- Blocks Cdk2 activation
- Induces growth arrest at G1-S and early S
- Effective in arresting growth of EGFR overexpressor cells
- Suppresses BPV-1 transcription
- Inhibits Moloney murine leukemia virus replication
Medchemexpress LLC Silver diethyldithiocarbamate | 1470-61-7 | MFCD00004929 | 256.1 g/mol | C5H10AgNS2 | 50 G
Silver diethyldithiocarbamate is a silver(I) salt of diethyldithiocarbamate used primarily as a reagent in analytical chemistry and as a metal-complexing agent. It is typically a white to pale-yellow solid with molecular formula C5H10AgNS2 and molecular weight 256.1 g/mol (CAS 1470-61-7).
- Used for colorimetric determination of arsenic in analytical methods.
- Forms stable complexes with transition metal ions.
- Available as a solid powder suitable for reagent preparation and analysis.
- Soluble in select organic solvents such as pyridine.
- High purity grades (commonly reported as ≥98% by suppliers) suitable for analytical use.
Medchemexpress LLC AG-636 | 1623416-31-8 | 98.07% | 343.38 | 1 ML
AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor. With an IC50 of 17 nM, it demonstrates strong anticancer effects and growth-inhibitory activity in various cancer cell lines. It has also shown robust tumor growth inhibition in xenograft lymphoma models.
- Potent, reversible, selective, and orally active DHODH inhibitor
- IC50 of 17 nM against DHODH
- Strong growth-inhibitory activity in cancer cell lines of hematologic versus solid tumor origin
- Robust tumor growth inhibition in xenograft lymphoma models
- Currently in phase 1 clinical trial for lymphoma
Medchemexpress LLC AG-636 | 1623416-31-8 | 98.07% | 343.38 | 25 MG
AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor. It demonstrates strong anticancer effects by inhibiting DHODH with an IC50 of 17 nM.
- Potent, reversible, selective, and orally active DHODH inhibitor
- Inhibits dihydroorotate dehydrogenase (DHODH) with an IC50 of 17 nM
- Exhibits strong growth-inhibitory activity in cancer cell lines
- Demonstrates robust tumor growth inhibition in xenograft lymphoma tumor models
Medchemexpress LLC AG-636 | 1623416-31-8 | 98.1% | 343.38 | 5 MG
AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. It demonstrates strong anticancer effects.
- Exhibits strong growth-inhibitory activity in cancer cell lines of both hematologic and solid tumor origin.
- Functions as a dihydroorotate dehydrogenase (DHODH) inhibitor.
- Applications:
- In vitro: has shown strong growth-inhibitory activity in various cancer cell lines.
- In vivo: treatment resulted in robust tumor growth inhibition in the OCILY19 DLBCL tumor xenograft model.
- Clinical trials: being investigated in a Phase 1 clinical trial (NCT03834584) for lymphoma, which started on May 24, 2019.
Medchemexpress LLC Silver diethyldithiocarbamate | 1470-61-7 | MFCD00004929 | 99.2% | 256.14 g/mol | C5H10AgNS2 | 10 G
Silver diethyldithiocarbamate is the silver salt of diethyldithiocarbamic acid supplied as a high-purity powder for laboratory analytical use. It acts as a chelating reagent that forms colored complexes with metal ions and is used in colorimetric and spectroscopic metal determinations.
- High purity suitable for analytical applications.
- Forms stable complexes with transition metals for colorimetric assays.
- Available in multiple pack sizes to support varied laboratory needs.
- Documentation available (COA and SDS) for quality and safety verification.
- Solid powder form for convenient reagent preparation and storage.
Medchemexpress LLC HY-10617 200mg , Rucaparib (phosphate) AG-014699 phosphate;PF-01367338 phosphate CAS:459868-92-9 Purity:98%
Medchemexpress, HY-10617 200mg Rucaparib (phosphate) AG-014699 phosphate;PF-01367338 phosphate CAS:459868-92-9 Formula:C19H21FN3O5P Ki: 1.4 nM (PARP1) Purity:98% Rucaparib (phosphate) is an inhibitor of PARP with K i of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP domains. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.