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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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STO-609 is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. It inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
Selective inhibitor of CaM-KK
Cell-permeable
Inhibits AMPKK activity
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STO-609 is a specific inhibitor of the Ca2 /Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KK and CaM-KK isoforms with Ki values of 80 and 15 ng/ml respectively and also inhibits their autophosphorylation activities STO-609 inhibits AMPKK activity and inhibits autophagy
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STO-609 is a specific inhibitor of the Ca2 /Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KK and CaM-KK isoforms with Ki values of 80 and 15 ng/ml respectively and also inhibits their autophosphorylation activities STO-609 inhibits AMPKK activity and inhibits autophagy
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STO-609 is a specific inhibitor of the Ca2 /Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KK and CaM-KK isoforms with Ki values of 80 and 15 ng/ml respectively and also inhibits their autophosphorylation activities STO-609 inhibits AMPKK activity and inhibits autophagy
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FHD-609 acts as a selective inhibitor and degrader of BRD9 protein (bromodomain-containing protein 9) FHD-609 targets ncBAF and can be used in research of various cancers involving mutations in a BAF complex subunit
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