FGF-21 Protein, Mouse (HEK293, His) influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression, particularly with KLB's presence. It plays a crucial role in systemic glucose homeostasis and insulin sensitivity, interacting directly with KLB through its C-terminus and engaging with FGFR4. The protein's molecular mechanisms involve a complex interplay, emphasizing its broad impact beyond localized effects. It is the recombinant mouse-derived FGF-21 protein, expressed by HEK293, with a C-6*His labeled tag.
- Influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression.
- Plays a crucial role in systemic glucose homeostasis and insulin sensitivity.
- Interacts directly with KLB through its C-terminus and engages with FGFR4.
- Recombinant mouse-derived protein.
- Expressed by HEK293.
- Features a C-6*His labeled tag.