Phenols
DL-3,4-Dihydroxymandelic Acid 98.0+%, TCI America™
CAS: 775-01-9 Molecular Formula: C8H8O5 Molecular Weight (g/mol): 184.147 MDL Number: MFCD00004231 InChI Key: RGHMISIYKIHAJW-UHFFFAOYSA-N PubChem CID: 85782 ChEBI: CHEBI:27637 IUPAC Name: 2-(3,4-dihydroxyphenyl)-2-hydroxyacetic acid SMILES: C1=CC(=C(C=C1C(C(=O)O)O)O)O
Apexbio Technology LLC HG-9-91-01 1456858-58-4 100mg
HG-9-91-01 (CAS 1456858-58-4) is a small-molecule inhibitor of salt-inducible kinases (SIK) selectively targeting SIK1 SIK2 and SIK3 with IC50 values of 0 92 nM 6 6 nM and 9 6 nM respectively SIK inhibition results in enhanced CREB-dependent gene transcription and elevated IL-10 production in response to LPS stimulation while decreasing pro-inflammatory cytokine secretion and promoting regulatory macrophage differentiation HG-9-91-01 also displays inhibitory activity against several protein tyrosine kinases including Src BTK FGF receptors and Ephrin receptors but does not notably affect other AMPK-related kinase subfamily members This compound is used in research addressing inflammatory and autoimmune disorders
Apexbio Technology LLC 8-Bromo-cGMP, sodium salt 51116-01-9 25mg
8-Bromo-cGMP sodium salt (CAS 51116-01-9) is a membrane-permeable analog of cyclic GMP that functions as an activator of protein kinase G (PKG) By mimicking endogenous cGMP it modulates intracellular signaling pathways notably influencing Ca2 channel activity Studies indicate that 8-Bromo-cGMP sodium salt can suppress macroscopic ionic currents and reduce insulin secretion under high K stimulation Due to its role in signal transduction and vascular function this compound is frequently employed in research addressing nociceptive modulation and vascular biology
Apexbio Technology LLC 8-Bromo-cGMP, sodium salt 51116-01-9 10mg
8-Bromo-cGMP sodium salt (CAS 51116-01-9) is a membrane-permeable analog of cyclic GMP that functions as an activator of protein kinase G (PKG) By mimicking endogenous cGMP it modulates intracellular signaling pathways notably influencing Ca2 channel activity Studies indicate that 8-Bromo-cGMP sodium salt can suppress macroscopic ionic currents and reduce insulin secretion under high K stimulation Due to its role in signal transduction and vascular function this compound is frequently employed in research addressing nociceptive modulation and vascular biology
Apexbio Technology LLC 8-Bromo-cGMP, sodium salt 51116-01-9 50mg
8-Bromo-cGMP sodium salt (CAS 51116-01-9) is a membrane-permeable analog of cyclic GMP that functions as an activator of protein kinase G (PKG) By mimicking endogenous cGMP it modulates intracellular signaling pathways notably influencing Ca2 channel activity Studies indicate that 8-Bromo-cGMP sodium salt can suppress macroscopic ionic currents and reduce insulin secretion under high K stimulation Due to its role in signal transduction and vascular function this compound is frequently employed in research addressing nociceptive modulation and vascular biology
Medchemexpress LLC 8-bromo-cGMP (sodium) | 51116-01-9 | 99.9% | 446.08 | C10H10BrN5NaO7P | 1 ML
8-Bromo-cGMP sodium is a membrane-permeable analogue of cyclic guanosine monophosphate (cGMP) used to activate protein kinase G (PKG) in biochemical and cellular assays. It is available as a ready-to-use 10 mM solution (1 mL) and in solid quantities for custom preparation.
- Membrane-permeable analogue of cGMP for PKG activation.
- Ready-to-use 10 mM solution format simplifies dosing.
- Also available as solid quantities for custom preparation.
- High purity (~99.9%) for reliable experimental results.
- Well characterized with molecular weight 446.08 and CAS 51116-01-9 for identification.
Medchemexpress LLC 8-bromo-cGMP sodium | 51116-01-9 | 99.9% | 446.08 | C10H10BrN5NaO7P | 25 MG
8-Bromo-cGMP sodium is a membrane-permeable analogue of cyclic guanosine monophosphate (cGMP) that acts as a protein kinase G (PKG) activator. It is used in biochemical and cellular research to probe cGMP-dependent signaling pathways involved in vascular tone, nociception, calcium channel modulation, and insulin secretion.
- Membrane-permeable cGMP analogue for intracellular delivery
- Activates protein kinase G (PKG) in functional assays
- Modulates calcium channel activity and insulin secretion pathways
- Useful for studies of vasodilation and nociception
- Available as solid and aqueous solution formats
- High purity suitable for research applications
Medchemexpress LLC 8-bromo-cGMP sodium | 51116-01-9 | 99.9% | 446.08 | C10H10BrN5NaO7P | 100 MG
8-Bromo-cGMP sodium is a membrane-permeable cyclic GMP analogue that activates protein kinase G (PKG). Supplied as the sodium salt in solid form at high purity, it is used as a research reagent to probe cGMP signaling pathways, modulate ion channel activity, and study vascular and neuronal responses. Store sealed at -20°C; in solvent, store at -80°C for longer-term stability.
- Membrane-permeable analogue of cGMP that activates protein kinase G (PKG).
- High purity (99.9%) suitable for biochemical and cellular assays.
- Off-white to light yellow solid for straightforward handling.
- Available in lab-scale quantities, including 100 MG.
- Stable when stored sealed at -20°C; in solvent, store at -80°C for up to 6 months.
- Used to study cGMP signaling, ion channel modulation, and vascular or neuronal pharmacology.
Medchemexpress LLC 8-Bromo-cGMP sodium | 51116-01-9 | 99.9% | 446.08 g/mol | C10H10BrN5NaO7P | 50 MG
8-Bromo-cGMP sodium is a membrane-permeable cyclic GMP analogue used to activate protein kinase G (PKG) in biochemical and cellular research. It mimics intracellular cGMP signaling and is commonly used to probe cGMP-dependent pathways in pharmacological and physiological studies.
- Membrane-permeable cyclic GMP analogue
- Activates protein kinase G (PKG) in biochemical assays
- High purity suitable for research use (99.89% per manufacturer)
- Solid form, off-white to light yellow appearance
- Available in small solid packages for experimental use
- Stable when stored sealed and protected from moisture; in solvent: -80°C for 6 months, -20°C for 1 month
