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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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ARL67156 trisodium hydrate is the trisodium salt hydrate form of ARL67156 (FPL 67156), a small-molecule inhibitor of ecto-ATPases used in research to study extracellular ATP signaling and disease models such as calcific aortic valve disease and asthma.
Inhibits ecto-ATPase enzymes, including NTPDase1 (CD39), NTPDase3, and NPP1.
Reported Ki values: 11 μM, 18 μM, and 12 μM for NTPDase1, NTPDase3, and NPP1, respectively.
Purity 99.94% as reported on the product page.
Supplied as a trisodium hydrate salt.
Available in small research quantities (for example, 1 mg and 5 mg sizes).
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Amino-PEG3-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker, with one targeting an E3 ubiquitin ligase and the other targeting the protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Contains two different ligands connected by a linker
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This compound leverages the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
Cleavable ADC linker
PEG-based PROTAC linker
Utilized in antibody-drug conjugate (ADC) synthesis
Used in PROTAC synthesis
Leverages intracellular ubiquitin-proteasome system
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Mosapride citrate is an orally active gastroenterokinetic compound. It acts as a 5HT4 agonist and a CYP inducer. It exhibits a concentration-dependent inhibitory effect on Kv4.3, with an IC50 value of 15.2 μM. Mosapride citrate is used in the study of gastrointestinal diseases.
Orally active gastroenterokinetic compound
5HT4 agonist
CYP inducer
Inhibitory effect on Kv4.3
Useful for studying gastrointestinal diseases
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Citric acid trilithium salt tetrahydrate (Trilithium citrate tetrahydrate Lithium citrate tribasic tetrahydrate) is a pharmaceutical and construction material It is commonly used in HPLC gradient elution for quantification of amino acids
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(E/Z)-Zotiraciclib citrate is a potent inhibitor targeting CDK2, JAK2, and FLT3. This compound is supplied as a solid, appearing off-white to light yellow, and is intended for research use only.
Potent CDK2, JAK2, and FLT3 inhibitor
High purity: 99.83%
Molecular weight: 564.59
Store at 4°C, sealed, away from moisture
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Gefapixant citrate is a P2X3 receptor antagonist provided as a concentrated solution for laboratory research. The reagent is supplied at 10 mM in DMSO (1 mL) and is intended for in vitro pharmacology and biochemical studies, with analytical documentation available from the manufacturer.
Ready-to-use 10 mM solution in DMSO, 1 mL.
High purity (99.2%) suitable for research applications.
Supports in vitro P2X3 receptor pharmacology and biochemical assays.
Comes with data sheet, certificate of analysis, and safety data sheet.
For research use only; not for human or diagnostic use.
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DMAPP (Dimethylallyl diphosphate) triammonium is an isoprenoid precursor found in virtually all life forms. It is an isomer of isopentenyl pyrophosphate (IPP) and plays a role in both the mevalonate and MEP pathways of isoprenoid precursor biosynthesis. The enzyme isopentenyl pyrophosphate isomerase catalyzes the isomerization between DMAPP and IPP.
Isoprenoid precursor
Isomer of isopentenyl pyrophosphate (IPP)
Found in virtually all life forms
Product of mevalonate and MEP pathways
Involved in isoprenoid precursor biosynthesis
Isomerization catalyzed by isopentenyl pyrophosphate isomerase
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2-Methylcitric acid trisodium is the trisodium salt of 2-methylcitric acid provided as a white to off-white solid for laboratory research. It is an endogenous metabolite used as a marker in methylmalonic and propionic acidemias and is employed in biochemical and mitochondrial studies, where it has been reported to inhibit ADP-stimulated mitochondrial respiration supported by glutamate.
Trisodium salt, white to off-white solid.
CAS number 117041-96-0.
Purity 96.0%.
Molecular weight 272.10 g·mol⁻1; formula C7H7Na3O7.
Highly soluble in water (100 mg/mL; may require ultrasonication).
Storage: sealed at 4°C; in solvent -80°C (6 months), -20°C (1 month).
For research use only; not for human or veterinary use.
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