Carboxylic acids and derivatives
eMolecules 52090-18-3 | Ambeed | (3-Bromopropyl)triethoxysilane | 1g | 660580810 | A1463762 | MFCD01862791 | 285.253 | C9H21BrO3Si
Ambeed | (3-Bromopropyl)triethoxysilane | 1g | 660580810 | A1463762 | 52090-18-3 | MFCD01862791 | 285.253 | C9H21BrO3Si
Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 50 MG
Asenapine maleate, a brain-penetrant atypical antipsychotic, acts as an antagonist of serotonin receptors, adrenoceptors, dopamine receptors, and histamine receptors. It is used in the research of schizophrenia and bipolar disorder.
- Exhibits high affinity for several serotonin, adrenergic, and dopamine receptors, indicating strong target engagement.
- Acts as a potent antagonist at various serotonin, dopamine, adrenergic, and histamine receptors.
- Demonstrates potential for superior therapeutic effect on anxiety symptoms in animal models.
- Shows anxiolytic-like effects in behavioral tests in mice.
Medchemexpress LLC VTP50469 fumarate | 2169919-29-1 | 99.8% | 804.93 g/mol | C32H47FN6O4S · 3/2 C4H4O4 | 5 MG
VTP50469 fumarate is the fumarate salt of VTP50469, a potent, highly selective, orally active inhibitor of the Menin-MLL (MLL1) protein-protein interaction. It has a reported Ki of 104 pM and demonstrates potent anti-leukemia activity in preclinical studies. The compound is supplied for research use with supporting datasheet, certificate of analysis, and safety data.
- Highly potent inhibitor with a reported Ki of 104 pM.
- Orally active compound effective in preclinical leukemia models.
- Selective mode of action targeting the Menin-MLL interaction.
- High purity suitable for biochemical and cellular studies.
- Supplied with datasheet, COA, and SDS for lab use.
- Available in small research quantities for preclinical experiments.
Selleck Chemical LLC Pimethixene maleate S3913-5mg
Pimethixene (Pimetixene) maleate an antihistamine anntimigraine agent and antiserotonergic compound is a highly potent antagonist of a broad range of monoamine receptors including a variety of serotonin receptors Pimethixene maleate inhibits 5-HT2A 5-HT2B 5-HT2C 5-HT1A 5-HT1B 5-HT6 5-HT7 Adrenergic -1A Dopamine D1 Receptor Dopamine D2 Receptor Dopamine D4 4 Receptor Histamine H1 Receptor Muscarinic M1 and Muscarinic M2 with pKi of 10 22 10 44 8 42 7 63 5 7 30 7 28 7 61 6 37 8 19 7 54 10 14 8 61 and 9 38 respectively
Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MG
Asenapine maleate (Org 5222 maleate) is a brain-penetrant atypical antipsychotic, serving as an antagonist for serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4), and histamine receptors (pKi: 8.2-9.0). This compound is valuable in the research of schizophrenia and bipolar disorder.
- Higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B, and D3 receptors compared to D2 receptor affinity.
- Demonstrated anxiolytic-like effects in animal models.
- Used for treating schizophrenia and bipolar I disorder.
Apexbio Technology LLC NB-598 Maleate 155294-62-5 10mg
NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
Medchemexpress LLC Velnacrine maleate | 118909-22-1 | HY-W011246 | 98.0% | 330.34 | 100 MG
Velnacrine maleate (HP 029) is an orally active cholinesterase inhibitor that can be used for the research of Alzheimer's disease.
- Orally active
- Cholinesterase inhibitor
- Used for research of Alzheimer's disease
Medchemexpress LLC Ilginatinib maleate | 1354799-87-3 | 99.87% | 505.50 | 50 MG
Ilginatinib maleate | 1354799-87-3 | 99.87% | 505.50 | 50 MG
Medchemexpress LLC 9(10H)-acridinone, 10-(3-aminopropyl)-3,4-dimethyl-, (2Z)-2-butenedioate (1:1) | 1204480-26-1 | 99.4% | 396.44 | 25 MG
ER-27319 (maleate), an acridone derivative, is a potent and selective SYK inhibitor. It inhibits the tyrosine phosphorylation of SYK and its activity. This compound also inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM, making it useful for studying allergic diseases.
- Potent and selective SYK inhibitor.
- Inhibits tyrosine phosphorylation of SYK and its activity.
- Inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM.
- Useful for study in allergic diseases.
- Available in solid form, yellow to orange color.
Medchemexpress LLC Quipazine maleate | 5786-68-5 | >98% | 50 MG
Quipazine maleate is a 5-HT agonist that causes behavioral changes such as hyperactivity. It also shows a weak reversible MAO inhibitory activity. This piperazine-based nonselective serotonin receptor agonist targets several 5-HT receptor subtypes, including 5-HT₂A (pKi ≈ 6.9), 5-HT₂C (≈ 7.27), and 5-HT₂B, as well as showing marked agonist activity at 5-HT₃ (EC₅₀ ≈ 1.0 nM). It has been explored for anti-parkinsonian potential in preclinical settings and is a valuable pharmacological tool for studying serotonin receptor functions.
- 5-HT agonist
- Causes behavioral changes such as hyperactivity
- Weak reversible MAO inhibitory activity
- Nonselective serotonin receptor agonist
- Targets 5-HT₂A, 5-HT₂C, 5-HT₂B, and 5-HT₃ receptors
- Explored for anti-parkinsonian potential
- Valuable pharmacological tool for studying serotonin receptor functions
TARGETMOL CHEMICALS INC PAMIDRONATE DISODIUM 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pamidronate Disodium (CGP 23339A) a nitrogen-containing bisphosphonate can help to strengthen bones. purity: 99%
![eMolecules 41575-94-4 | Carboplatin | Broadpharm369.240 | C6H10N2O4Pt | 0.000 | [NH2-].[NH2-].[Pt+4].[O-]C(=O)C1(CCC1)C([O-])=O | 50mg | 573896669](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502458606.PNG-250.jpg)
eMolecules 41575-94-4 | Carboplatin | Broadpharm369.240 | C6H10N2O4Pt | 0.000 | [NH2-].[NH2-].[Pt+4].[O-]C(=O)C1(CCC1)C([O-])=O | 50mg | 573896669
Carboplatin | Broadpharm | 41575-94-4369.240 | C6H10N2O4Pt | 0.000 | [NH2-].[NH2-].[Pt+4].[O-]C(=O)C1(CCC1)C([O-])=O | 50mg | 573896669