Suramin sodium salt is a versatile compound acting as a reversible and competitive inhibitor of protein-tyrosine phosphatases (PTPases). It also inhibits sirtuins and reverse transcriptase. It has been identified as an antiparasitic, anti-neoplastic, and anti-angiogenic agent, and is also a potent inhibitor of SARS-CoV-2 RNA-dependent RNA polymerase (RdRp).
- Reversible and competitive PTPases inhibitor
- Potent inhibitor of sirtuins (SirT1, SirT2, SirT5)
- Competitive inhibitor of reverse transcriptase (DNA topoisomerase II)
- Potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor
- Efficiently inhibits IP5K
- Acts as an antiparasitic, anti-neoplastic, and anti-angiogenic agent