Azoles
Aobchem 1-(2-Phenylthiazol-5-yl)ethanone | ≥95% | CAS 10045-50-8 | C11H9NOS | 1g
1-(2-Phenylthiazol-5-yl)ethanone | ≥95% | CAS 10045-50-8 | C11H9NOS | 1g
Medchemexpress LLC 3-Chloro-N-(4-hydroxy-2-oxo-2H-chromen-3-yl)benzamide | 94205-22-8 | C16H10ClNO4 | 5 MG
Anticancer agent 93 is a 4-Hydroxycoumarin derivative that inhibits invasion and migration of lung cancer cells by modulating the expression of epithelial-mesenchymal transition (EMT) effectors. In vitro, it significantly inhibits A549 cell invasion and migration, and lung cancer cell motility by downregulating EMT markers.
- Acts as a 4-hydroxycoumarin derivative
- Inhibits invasion and migration of lung cancer cells
- Modulates the expression of epithelial-mesenchymal transition (EMT) effectors
- Significantly inhibits A549 cell invasion and migration in vitro
- Downregulates EMT markers to reduce lung cancer cell motility
Medchemexpress LLC 1H-Pyrrole-2-carboxamide, N-[4-(5-thiazolyl)phenyl]-4-[2-(trifluoromethyl)benzoyl]- | 3056857-07-6 | 99.8% | 441.43 | 25 MG
1H-Pyrrole-2-carboxamide, N-[4-(5-thiazolyl)phenyl]-4-[2-(trifluoromethyl)benzoyl]- | 3056857-07-6 | 99.8% | 441.43 | 25 MG
Medchemexpress LLC Cis VH-298 | 2097381-86-5 | 100.0% | 523.65 g/mol | C27H33N5O4S | 5 MG
Cis VH-298 is the cis geometric isomer of VH-298 that shows a significant loss of binding specificity of hydroxylated HIF-1α peptides to the von Hippel-Lindau (VHL) protein in vitro. Supplied as a high-purity research-grade small molecule, it is intended for laboratory studies of VHL-HIF interactions and to serve as a stereochemical control when comparing isomer effects.
- High purity suitable for analytical and cell-based research.
- Provided in research-scale quantities for experimental use.
- Useful as a stereochemical control to compare cis/trans activity.
- Demonstrates reduced VHL binding, aiding mechanistic studies of HIF regulation.
- Includes datasheet with chemical properties and handling information.
- For research use only; not for human or diagnostic use.