Azoles
Medchemexpress LLC 2'-O-Methyladenosine | 2140-79-6 | 99.8% | 281.27 | 100 MG
2'-O-Methyladenosine is a methylated adenine residue found in the urine of both normal individuals and adenosine deaminase (ADA) deficient patients. It exhibits unique hypotensive activities.
- Human endogenous metabolite.
- Exhibits unique hypotensive activities in rats.
- Decreased blood pressure by about 40-50% in male spontaneously hypertensive rats.
Medchemexpress LLC Adefovir dipivoxil | 142340-99-6 | 99.0% | 500 MG
Adefovir dipivoxil is an orally active adenosine analog and Adefovir prodrug. It inhibits DNA synthesis, activates the ATR signaling pathway, and disrupts the KCTD12-CDK1 interaction. This compound exhibits antiviral activity against PRV, HBV, and orthopoxviruses. Additionally, it shows antitumor activity against lung and colon cancer.
- Orally active adenosine analog and prodrug of Adefovir
- Inhibits DNA synthesis
- Activates the ATR signaling pathway
- Disrupts the KCTD12-CDK1 interaction
- Exhibits antiviral activity against PRV, HBV, and orthopoxviruses
- Effective against both lamivudine-resistant and wild-type strains
- Shows antitumor activity against lung and colon cancer
- Intended for research use only
Medchemexpress LLC HY-A0006 50mg , Pentostatin Deoxycoformycin CAS:53910-25-1 Purity:98%
Medchemexpress, HY-A0006 50mg Pentostatin Deoxycoformycin CAS:53910-25-1 Formula:C11H16N4O4 Ki: 2.5 pM (adenosine deaminase) Purity:98% Pentostatin is an irreversible inhibitor of adenosine deaminase with K i of 2.5 pM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Rad16-I (hydrochloride) | 2100275-49-6 | 98.9% | 5 MG
RAD16-I hydrochloride is a soft nanofibrous self-assembling peptide. It provides a suitable microenvironment for human mesenchymal stem cells' (hMSC) proliferation and differentiation into chondrocytes. This ionic complementary peptide is also used as a model to check potential amyloid-like staining properties of self-assembling peptide nanofibers (SAPNFs).
- Provides a suitable microenvironment for human mesenchymal stem cells' (hMSC) proliferation and differentiation into chondrocytes.
- Used as a model to check potential amyloid-like staining properties of self-assembling peptide nanofibers (SAPNFs).
- Intended for research use only.
- Suitable for laboratory use.
Medchemexpress LLC Delamanid-d4 | 681492-22-8 | 98.0% | 538.51 | 2 MG
Delamanid-d4 is the deuterium labeled Delamanid, a newer mycobacterial cell wall synthesis inhibitor. It inhibits the synthesis of mucolic acids and is intended for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Inhibits the synthesis of mucolic acids.
- Deuterium-labeled compound.
Medchemexpress LLC HY-111646 5mg Medchemexpress, N6-Etheno 2'-deoxyadenosine CAS:68498-25-9 Purity:>98%
Medchemexpress, HY-111646 5mg N6-Etheno 2'-deoxyadenosine CAS:68498-25-9 N6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0028 100mg Medchemexpress, Fludarabine (phosphate) CAS:75607-67-9 Purity:98%
Medchemexpress,HY-B0028 100mg Fludarabine (phosphate) CAS:75607-67-9 Formula:C10H13FN5O7P Fludarabine (phosphate) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC 5H-imidazo[2,1-b]oxazine, 6,7-dihydro-2-nitro-6-[[6-[4-(trifluoromethoxy)phenyl]-3-pyridinyl]methoxy] | 1257426-19-9 | 99.7% | 436.34 | C19H15F3N4O5 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236436.png-250.jpg)
Medchemexpress LLC 5H-imidazo[2,1-b]oxazine, 6,7-dihydro-2-nitro-6-[[6-[4-(trifluoromethoxy)phenyl]-3-pyridinyl]methoxy] | 1257426-19-9 | 99.7% | 436.34 | C19H15F3N4O5 | 100MG
TBA-354 is a nitroimidazole-class anti-tuberculosis research compound with reported activity against Mycobacterium tuberculosis, including some monoresistant strains. It is provided as a high-purity solid and as ready-to-use DMSO solutions for use in antimicrobial screening and efficacy studies.
- Molecular formula C19H15F3N4O5.
- Molecular weight 436.34.
- CAS number 1257426-19-9.
- Purity 99.7%.
- Supplied as solid and as 10 mM solution in DMSO.
- Available in small-scale quantities from 5 mg up to 500 mg.
- Demonstrates bactericidal activity against M. tuberculosis strains.
- Intended for research use in in vitro and in vivo studies.
![eMolecules 174899-82-2 | 1-Ethyl-3-methyl?imidazolium bis(trifluoromethylsulfonyl)imide, 99% [EMIIm] | Strem Chemicals | MFCD11865028 | 391.300 | C8H11F6N3O4S2 | 99.000 | CC[n+]1ccn(C)c1.FC(F)(F)S(=O)(=O)[N-]S(=O)(=O)C(F)(F)F | 1g | 321334782](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502169125.JPG-250.jpg)
eMolecules 174899-82-2 | 1-Ethyl-3-methyl?imidazolium bis(trifluoromethylsulfonyl)imide, 99% [EMIIm] | Strem Chemicals | MFCD11865028 | 391.300 | C8H11F6N3O4S2 | 99.000 | CC[n+]1ccn(C)c1.FC(F)(F)S(=O)(=O)[N-]S(=O)(=O)C(F)(F)F | 1g | 321334782
1-Ethyl-3-methyl?imidazolium bis(trifluoromethylsulfonyl)imide, 99% [EMIIm] | Strem Chemicals | 174899-82-2 | MFCD11865028 | 391.300 | C8H11F6N3O4S2 | 99.000 | CC[n+]1ccn(C)c1.FC(F)(F)S(=O)(=O)[N-]S(=O)(=O)C(F)(F)F | 1g | 321334782
![Medchemexpress LLC 5-[(E)-2-thiophen-2-ylethenyl]-1H-pyrazole | 1070881-42-3 | 99.9% | C9H8N2S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000258416.png-250.jpg)
Medchemexpress LLC 5-[(E)-2-thiophen-2-ylethenyl]-1H-pyrazole | 1070881-42-3 | 99.9% | C9H8N2S | 10MG
Terevalefim (ANG-3777) is a small-molecule hepatocyte growth factor (HGF) mimetic that selectively activates the c-Met receptor. It has been used in preclinical studies to decrease apoptosis, increase cellular proliferation, and promote organ repair and function. For research use only; not for clinical use or sale to patients.
- Selectively activates the c-Met receptor in cellular assays.
- Demonstrated to decrease apoptosis and promote proliferation in preclinical models.
- High chemical purity suitable for research applications.
- Solid, white to light brown appearance for convenient handling and storage.
- Soluble in DMSO at high concentration; ultrasonic agitation recommended.
- Stable when stored under recommended cryogenic conditions.
Apexbio Technology LLC BRD4770 1374601-40-7 10mg
BRD4770 (CAS 1374601-40-7) is a small-molecule inhibitor targeting the histone methyltransferase G9a with an IC50 of 6 3 M In studies using the PANC-1 pancreatic cancer cell line BRD4770 was shown to decrease levels of di- and trimethylated histone H3 lysine 9 (H3K9) through inhibition of G9a activity This reduction in H3K9 methylation is associated with the induction of cellular senescence and cell death as well as suppression of both adherent-dependent and independent cell proliferation BRD4770 serves as a useful probe for exploring the epigenetic regulation of gene expression and cellular senescence in cancer biology research
Medchemexpress LLC Akt-in-6 | 1430056-54-4 | 99.1% | 389.43 | 5 MG
AKT-IN-6 is a potent Akt inhibitor that inhibits Akt1, Akt2, and Akt3 with IC50s less than 500 nM.
- Potent Akt inhibitor.
- Inhibits Akt1, Akt2, and Akt3.
- Available in solid form (yellow to brown color).
- Soluble in DMSO (125 mg/mL).
- Multiple package sizes are available (5 mg to 100 mg).
- Associated with various related screening libraries, small molecules, and proteins.
Accela Chembio Inc 1-hexyl-3-methylimidazolium Tetrafluoroborate | 100g | 244193-50-8 | MFCD03095459 | 97+% | D: 1.149 | Shelf Life: 1440 Days | Moisture Sensitive/n2
1-hexyl-3-methylimidazolium Tetrafluoroborate | 100g | 244193-50-8 | MFCD03095459 | 97+% | D: 1.149 | Shelf Life: 1440 Days | Moisture Sensitive/n2
Accela Chembio Inc 1-hexyl-3-methylimidazolium Tetrafluoroborate | 25g | 244193-50-8 | MFCD03095459 | 97+% | D: 1.149 | Shelf Life: 1440 Days | Moisture Sensitive/n2
1-hexyl-3-methylimidazolium Tetrafluoroborate | 25g | 244193-50-8 | MFCD03095459 | 97+% | D: 1.149 | Shelf Life: 1440 Days | Moisture Sensitive/n2
![eMolecules 3056-33-5 | N,9-Diacetylguanine | Combi-Blocks | MFCD00142116 | 235.203 | C9H9N5O3 | 95.000 | CC(=O)Nc1nc2n(cnc2c(=O)[nH]1)C(C)=O | 5g | 205386045](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502184098.JPG-250.jpg)
eMolecules 3056-33-5 | N,9-Diacetylguanine | Combi-Blocks | MFCD00142116 | 235.203 | C9H9N5O3 | 95.000 | CC(=O)Nc1nc2n(cnc2c(=O)[nH]1)C(C)=O | 5g | 205386045
N,9-Diacetylguanine | Combi-Blocks | 3056-33-5 | MFCD00142116 | 235.203 | C9H9N5O3 | 95.000 | CC(=O)Nc1nc2n(cnc2c(=O)[nH]1)C(C)=O | 5g | 205386045