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Organic compounds that consist of a phenyl group attached to an amino group; aniline is the simplest aromatic amine. Anilines with additional substitutions are included.
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4-Bromo-2-methoxyaniline is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. It has a purity of 99.71% and a chemical formula of C7H8BrNO. It is for research use only and not sold to patients.
Biochemical reagent for life science-related research
High purity (99.71%)
Chemical formula: C7H8BrNO
For research use only
Storage at 4°C, protected from light; in solvent: -80°C for 6 months, -20°C for 1 month (protected from light)
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DuP-697 (CAS 88149-94-4) is a selective, irreversible cyclooxygenase-2 (COX-2) inhibitor used as a research chemical. It inhibits prostaglandin synthesis and has demonstrated antiproliferative, antiangiogenic, and antipyretic effects in cellular studies. The compound is provided as a high-purity solid for biochemical assays and preclinical research; it is not intended for human or veterinary use.
Selective, irreversible COX-2 inhibition (IC50 ≈ 10 nM for human COX-2)
Minimal COX-1 activity (IC50 ≈ 800 nM for human COX-1)
High purity (≈99.8%) suitable for analytical and biological studies
Molecular weight 411.31 g·mol⁻¹; formula C17H12BrFO2S2
Suitable for biochemical assays and cell-based research; research use only
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PSI-697 is a small-molecule, orally active P-selectin inhibitor in the quinoline-carboxylic acid series that was investigated for antithrombotic and anti-inflammatory effects in preclinical models and early clinical studies.
Orally active small-molecule P-selectin inhibitor.
Characterized in vitro and in rodent models for antithrombotic activity.
Reported in vitro P-selectin inhibition in the 50-125 μM range.
High reported purity suitable for research use.
Available in multiple small pack sizes for laboratory studies.
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DuP-697 is an irreversible and specific inhibitor of COX-2 with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1. DuP-697 shows antiproliferative activity with an IC50 of 42.8 nM. DuP-697 exhibits antiangiogenic anti-inflammatory antipyretic and apoptotic effects. purity: 100%
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DuP 697 (CAS 88149-94-4) is an ortho-diaryl heterocyclic compound that selectively and irreversibly inhibits cyclooxygenase-2 (COX-2) displaying an IC50 of 10 nM for human COX-2 and 800 nM for COX-1 DuP 697 is demonstrated to suppress prostaglandin synthesis and in vitro exhibits antiproliferative pro-apoptotic and anti-angiogenic effects in HT29 colorectal cancer cells (IC50 42 8 nM) This small molecule is commonly utilized to explore COX-2-mediated inflammatory pathways as well as tumor biology providing a valuable tool for dissecting mechanisms underlying inflammation and cancer
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DuP 697 (CAS 88149-94-4) is an ortho-diaryl heterocyclic compound that selectively and irreversibly inhibits cyclooxygenase-2 (COX-2) displaying an IC50 of 10 nM for human COX-2 and 800 nM for COX-1 DuP 697 is demonstrated to suppress prostaglandin synthesis and in vitro exhibits antiproliferative pro-apoptotic and anti-angiogenic effects in HT29 colorectal cancer cells (IC50 42 8 nM) This small molecule is commonly utilized to explore COX-2-mediated inflammatory pathways as well as tumor biology providing a valuable tool for dissecting mechanisms underlying inflammation and cancer
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
DuP-697 (CAS 88149-94-4) is a selective, irreversible cyclooxygenase-2 (COX-2) inhibitor provided as a solid research reagent for biochemical and cell-based assays. It exhibits potent inhibition of human COX-2 with marked selectivity over COX-1 and is used to investigate prostaglandin-mediated inflammation and related pharmacology.
Selective, irreversible COX-2 inhibitor with hCOX-2 IC50 = 10 nM.
High purity solid suitable for biochemical and cell-based assays.
Demonstrates activity in cellular models and animal inflammation assays.
Stable as a powder at -20°C for long-term storage; limit solvent storage to -80°C for extended periods.
Useful tool compound for studies of prostaglandin synthesis and inflammation pathways.
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