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Filtered Search Results
eMolecules 150725-87-4 | Medchem Express | Ro 46-2005 | 5mg | 446269889 | HY-19529 | MFCD00918670 | 473.54 | C23H27N3O6S
Ambeed | (35-Difluoro-4-propoxyphenyl)boronic acid | 100mg | 717401517 | A363125 | 2096331-43-8 | MFCD20231441 | 215.990 | C9H11BF2O3
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Medchemexpress LLC HY-18253 5mg Medchemexpress, Udenafil CAS:268203-93-6 Purity:>98%
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Medchemexpress, HY-18253 5mg Udenafil CAS:268203-93-6 Udenafil (DA8159) is a potent, selective and orally active phosphodiesterase type 5 (PDE5) inhibitor. Udenafil also inhibits cGMP hydrolysis and can be used for erectile dysfunction research. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Tamsulosin hydrochloride British Pharmacopoeia (BP) Reference Standard | 106463-17-6 | MFCD00922997 |
Tamsulosin hydrochloride British Pharmacopoeia (BP) Reference Standard | Mol Wt: 444.97 | 106463-17-6 | MFCD00922997 |
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Frontier Specialty Chemicals 5G 4- (3-BROMOBENZENE)SULFONYL
4-[(3-Bromobenzene)sulfonyl]morpholine; CAS: 871269-13-5; 5g
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eMolecules 942206-85-1 | Medchem Express | GSK1016790A | 5mg | 446269983 | HY-19608 | MFCD12912413 | 655.61 | C28H32Cl2N4O6S2
Medchem Express | GSK1016790A | 5mg | 446269983 | HY-19608 | 942206-85-1 | MFCD12912413 | 655.610 | C28H32Cl2N4O6S2
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Medchemexpress LLC HY-B0397 10mg Medchemexpress, Dichlorphenamide CAS:120-97-8 Purity:>98%
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Medchemexpress, HY-B0397 10mg Dichlorphenamide CAS:120-97-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Sulfaguanidine 57-67-0 50mg
Sulfaguanidine (57-67-0) is a small-molecule inhibitor targeting bacterial dihydropteroate synthase It is designed to competitively inhibit this enzyme thereby interfering with folic acid biosynthesis and disrupting a pathway critical for bacterial growth Sulfaguanidine exerts its biological activity primarily through competitive inhibition of bacterial dihydropteroate synthase In in vitro infection models sulfaguanidine demonstrates antimicrobial activity with reported IC50 values generally in the micromolar range depending on bacterial species experimental conditions and assay methodologies Based on these pharmacological properties sulfaguanidine holds research potential in studies of antimicrobial resistance mechanisms bacterial folate metabolism and interactions with other antimicrobial agents
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Medchemexpress LLC Abt-199 5Mg | HY-15531-5MG
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Abt-199 5Mg
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Medchemexpress LLC HY-101486 5mg Medchemexpress, LF3 CAS:664969-54-4 Purity:>98%
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Medchemexpress, HY-101486 5mg LF3 CAS:664969-54-4 LF3 is an antagonist of the β-Catenin/TCF4 interaction with antitumor activity; has an IC 50 of 1.65 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1808094-07-6 | Medchem Express | PF-06471553 | 5mg | 446259309 | HY-108339 | 467.54 | C23H25N5O4S
Ambeed | (S)-4-Cyclohexyl-2-(pyridin-2-ylmethyl)-45-dihydrooxazole | 100mg | 719807363 | A1496233 | 2757085-29-1 | 244.338 | C15H20N2O
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Medchemexpress LLC PHT-7.3 | 1614225-93-2 | 99.29% | 100 MG
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PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (Kd=4.7 μM). It inhibits mutant KRas, but not wild-type KRas cancer cell and tumor growth and signaling, demonstrating antitumor activity.
- Selective inhibitor of Cnk1 PH domain.
- Inhibits mutant KRas cancer cell and tumor growth.
- Demonstrates antitumor activity.
- Exhibits cytostatic antitumor activity in mut-KRas xenograft models.
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Apexbio Technology LLC WAY 316606(Synonyms: WAY-316606, WAY316606, WAY 316606 sFRP-1 inhibitor, sFRP-1 inhibitor WAY 316606), 5mg, CAS: 915759-45-4.
WAY 316606 (CAS 915759-45-4) is a selective small molecule inhibitor targeting secreted frizzled-related protein 1 (sFRP-1) an endogenous antagonist of Wnt signaling WAY 316606 binds specifically to sFRP-1 (Kd 0 08 M) reducing its inhibitory effect and thus activating the canonical Wnt pathway In cell-based reporter assays using U2-OS osteosarcoma cells WAY 316606 dose-dependently promoted Wnt signaling with an EC50 of 0 65 M Ex vivo studies with neonatal murine calvarial tissue further demonstrated that WAY 316606 enhances osteoblast activity and bone formation This compound serves as a research tool for investigating Wnt-associated bone metabolism and therapeutic strategies for metabolic bone disorders
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Medchemexpress LLC Gliclazide-d4 | 1185039-30-8 | 99.9% | 1 MG
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Gliclazide-d4 is the deuterium-labeled form of Gliclazide, which acts as a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic.
- This compound can be used as a tracer.
- It can serve as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration, the incorporation of stable heavy isotopes into drug molecules, has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC Etebenecid | 1213-06-5 | 99.7% | 50 MG
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Etebenecid is a uricosuric agent that promotes the excretion of uric acid in urine, and also inhibits the renal tubular secretion of penicillin. This compound has a molecular weight of 257.31 and its chemical formula is C11H15NO4S. It presents as a solid with an appearance ranging from white to off-white. For in vitro applications, Etebenecid is soluble in DMSO at a concentration of 250 mg/mL, with ultrasonic assistance and freshly opened DMSO recommended due to its hygroscopic nature. For in vivo applications, it can be prepared as a clear solution using various solvent systems, including combinations of DMSO with PEG300, Tween-80, and saline; DMSO with SBE-β-CD in saline; or DMSO with corn oil.
- Functions as a uricosuric agent.
- Inhibits the renal tubular secretion of penicillin.
- High purity of 99.7%.
- Soluble in DMSO for in vitro studies.
- Can be formulated for in vivo studies using multiple solvent protocols.
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Medchemexpress LLC Furosemide | 54-31-9 | 99.83% | 1 G
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Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, specifically NKCC1 and NKCC2. It also acts as a GABAA receptors antagonist, displaying 100-fold selectivity for α6-containing receptors over α1-containing receptors. This compound functions as a loop diuretic and is widely used for the study of congestive heart failure, hypertension, and edema.
- Potent and orally active inhibitor of NKCC cotransporter (NKCC1 and NKCC2)
- GABAA receptors antagonist
- Displays 100-fold selectivity for α6-containing receptors
- Acts as a loop diuretic
- Used for studies of congestive heart failure
- Used for studies of hypertension
- Used for studies of edema
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