Benzenesulfonamides
Apexbio Technology LLC Glimepiride 93479-97-1 10mM (in 1mL DMSO)
Glimepiride (CAS 93479-97-1) is a sulfonylurea compound widely used in research on type 2 diabetes It primarily acts by enhancing glucose uptake both in the presence and absence of insulin In cultured cells glimepiride (10 M) increases 2-deoxyglucose uptake to 186% of control and upregulates GLUT1 and GLUT4 expression to 164% and 148% of control respectively indicating insulin-independent mechanisms for stimulating cardiac glucose uptake In rodent models glimepiride administration reduced diabetes incidence by 23% in BB rats and decreased blood glucose HbA1c and plasma insulin levels in KK-Ay mice highlighting its utility for investigating glucose metabolism and diabetes pathophysiology
Medchemexpress LLC HY-50907 200mg , ABT-737 CAS:852808-04-9 Purity:98%
Medchemexpress, HY-50907 200mg ABT-737 CAS:852808-04-9 Formula:C42H45ClN6O5S2 EC50: 78.7 nM (Bcl-xL), 30.3 nM (Bcl-2), 197.8 nM (Bcl-w) Purity:98% ABT-737 is a BH3 mimetic inhibitor of Bcl-xL , Bcl-2 and Bcl-w with EC 50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively, and shows no inhibition against Mcl-1, Bcl-B or Bfl-1. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![eMolecules Medchem Express / AKR1C3-IN-9 / 5mg / 785215445 / HY-152188 / / 2924824-43-9 / [null] / 352.390 / C20H20N2O4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502450283.PNG-250.jpg)
eMolecules Medchem Express / AKR1C3-IN-9 / 5mg / 785215445 / HY-152188 / / 2924824-43-9 / [null] / 352.390 / C20H20N2O4
Medchem Express / AKR1C3-IN-9 / 5mg / 785215445 / HY-152188 / / 2924824-43-9 / [null] / 352.390 / C20H20N2O4
eMolecules Medchem Express / SB756050 / 10mg / 446257568 / HY-102016 / / 447410-57-3 / MFCD02585318 / 500.580 / C21H28N2O8S2
Medchem Express / SB756050 / 10mg / 446257568 / HY-102016 / / 447410-57-3 / MFCD02585318 / 500.580 / C21H28N2O8S2
eMolecules Target Molecule Sildenafil citrate 50mg 335401181 T0467 0 000 171599-83-0 MFCD09026931 666 700 C28H38N6O11S
Target Molecule Sildenafil citrate 50mg 335401181 T0467 0 000 171599-83-0 MFCD09026931 666 700 C28H38N6O11S
eMolecules N-Ethyl 4-boronobenzenesulfonamide | 871329-65-6 | 5G | Purity: 98%
Combi-Blocks | N-Ethyl 4-boronobenzenesulfonamide | 5G | 871329-65-6 | MFCD07363751
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eMolecules Building Block Tool
eMolecules 1-(Thien-2-ylsulfonyl)piperazine | 565178-12-3 | 1G | Purity: 98%
Combi-Blocks | 1-(Thien-2-ylsulfonyl)piperazine | 1G | 565178-12-3 | MFCD03987297
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eMolecules Building Block Tool
Chem-Impex International, Inc. 4-Sulfamylbenzoic acid | 138-41-0 | MFCD00007938 | 25G
4-Sulfamylbenzoic acid, 138-41-0, MFCD00007938, 25G
Medchemexpress LLC Benzenesulphonamide | 98-10-2 | MFCD00007930 | 99.5% | 157.19 g/mol | C6H7NO2S | 5 G
Benzenesulphonamide is a high-purity analytical standard for biochemical and analytical research, commonly used as a carbonic anhydrase inhibitor reference and as a reagent for assay development and method validation. The compound is supplied as a solid in multiple pack sizes and is accompanied by safety and technical documentation.
- High purity for analytical applications (~99.5%).
- CAS number 98-10-2 for unambiguous identification.
- Molecular weight 157.19 g/mol.
- Chemical formula C6H7NO2S.
- Supplied as a solid, available in small pack sizes including 5 G.
- Suitable as a reference standard for enzyme inhibition and assay work.
- Provided with a safety data sheet for handling and storage.
Medchemexpress LLC HY-17621 5mg Medchemexpress, Sparsentan CAS:254740-64-2 Purity:>98%
Medchemexpress, HY-17621 5mg Sparsentan CAS:254740-64-2 Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-18741 5mg Medchemexpress, VR23 CAS:1624602-30-7 Purity:>98%
Medchemexpress, HY-18741 5mg VR23 CAS:1624602-30-7 VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC50=1 nM), chymotrypsin-like proteasomes (IC50=50-100 nM), and caspase-like proteasomes (IC50=3 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC PHT-7.3 | 1614225-93-2 | 99.3% | 433.52 g·mol⁻¹ | C24H23N3O3S | 5 MG
PHT-7.3 is a research-grade small-molecule inhibitor that targets the pleckstrin homology (PH) domain of connector enhancer of kinase suppressor of Ras 1 (Cnk1) and shows activity against mutant KRAS signaling. Supplied as a high-purity solid for in vitro research use only.
- Selective inhibitor of Cnk1 PH domain (Kd 4.7 μM).
- Preferentially inhibits mutant KRAS signaling over wild-type KRAS.
- High purity: 99.29%.
- Soluble in DMSO at 62.5 mg/mL; may require ultrasonication.
- Powder storage stability: -20°C for long-term, 4°C for short-term.
- Intended for research use only; not for human or clinical use.
eMolecules Medchem Express / (Z)-Thiothixene / 5mg / 446259291 / HY-108324 / / 3313-26-6 / MFCD00079574 / 443.620 / C23H29N3O2S2
Medchem Express / (Z)-Thiothixene / 5mg / 446259291 / HY-108324 / / 3313-26-6 / MFCD00079574 / 443.620 / C23H29N3O2S2