Benzenesulfonamides
Medchemexpress LLC Glimepiride | 1131981-29-7 | 99.4% | C24H30D4N4O5S | 1 MG
Glimepiride-d4-1 is a deuterium-labeled version of Glimepiride, a medium-to-long acting sulfonylurea anti-diabetic compound. This labeled compound can be used for quantitative analysis and tracing in various scientific applications.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Glimepiride-d5 | 1028809-90-6 | C24H29D5N4O5S | 1 MG
Glimepiride-d5 is the deuterium labeled Glimepiride, a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg. It is intended for research use only. This compound can be utilized as a tracer and as an internal standard for quantitative analysis. Deuterium labeling has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC N-desmethyl sildenafil-d8 | 1185168-06-2 | MFCD11977920 | 99.3% | 468.60 g/mol | C21H20D8N6O4S | 5 MG
N-Desmethyl sildenafil-d8 is a deuterium-labeled analytical standard of the N-desmethyl metabolite of sildenafil, provided in milligram quantities for research and quantitative analysis. It is intended for use as an internal standard in mass-spectrometry, pharmacokinetic, and metabolic studies, and is supplied with recommended storage conditions to preserve isotopic integrity.
- Deuterium-labeled internal standard for quantitative LC-MS/MS analysis.
- High purity suitable for analytical and pharmacokinetic studies.
- Supplied in small milligram amounts for precise measurements.
- Stable under recommended storage to maintain isotopic composition.
- Appropriate as a reference material for metabolite identification.
Medchemexpress LLC N-desmethyl sildenafil-d8 | 1185168-06-2 | 99.3% | 468.60 | C21H20D8N6O4S | 1 MG
N-Desmethyl Sildenafil-d8 is the deuterium-labeled form of N-desmethyl sildenafil supplied as a high-purity analytical standard for LC-MS/MS, pharmacokinetic, and metabolic studies. It provides a stable isotope internal standard for accurate quantitation and method development.
- Deuterium-labeled internal standard for mass spectrometry
- High purity (99.3%) for reliable quantitation
- Molecular formula C21H20D8N6O4S; molecular weight 468.60
- Available in small quantities suitable for analytical use (1 mg, 5 mg)
- Stable isotope reduces matrix effects and improves accuracy
Medchemexpress LLC Homo Sildenafil-d5 | 1216711-61-3 | 1 MG
Homo Sildenafil-d5 is the deuterium labeled Homo Sildenafil. Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Oregon green 488 azide | 2648246-11-9 | 98.0% | 637.67 | C33H37F2N5O6 | 10 MG
Oregon Green 488 azide is a green-fluorescent azide reagent used to label alkyne-modified biomolecules via copper-catalyzed azide-alkyne cycloaddition (click chemistry). It is supplied as a solid dye with high purity for biochemical assays and fluorescence labeling.
- Bright green-fluorescent azide probe for click chemistry.
- Reacts selectively with terminal alkynes via copper-catalyzed azide-alkyne cycloaddition.
- High purity (98.0%) suitable for biochemical assays.
- Solid, orange to red appearance for easy handling and storage.
- Storage: sealed, away from moisture and light; in solvent: -80°C (6 months), -20°C (1 month).
- Available in multiple pack sizes, including 10 MG.
Medchemexpress LLC Sildenafil-d3 | 1126745-90-1 | C22H27D3N6O4S | 5 MG
Sildenafil-d3 is a deuterium-labeled version of Sildenafil, a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. This compound is suitable for various analytical applications.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Appearance: solid.
- Color: white to off-white.
- Purity: 99.87%.
- Target: PDE5.
- Molecular weight: 477.59.
Medchemexpress LLC Gliclazide-d4 | 1185039-30-8 | 99.9% | 1 MG
Gliclazide-d4 is the deuterium-labeled form of Gliclazide, which acts as a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic.
- This compound can be used as a tracer.
- It can serve as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration, the incorporation of stable heavy isotopes into drug molecules, has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Gliclazide-d4 | 1185039-30-8 | 99.9% | 5 MG
Gliclazide-d4 is the deuterium-labeled form of Gliclazide, an antidiabetic agent that functions as a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Deuteration, the process of incorporating stable heavy isotopes like hydrogen and carbon into drug molecules, is used for quantitation during drug development and has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules.
- Largely used as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Furosemide-d5 | 1189482-35-6 | 99.9% | 1 MG
Furosemide-d5 is the deuterium labeled Furosemide. Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, specifically NKCC1 and NKCC2. It also acts as a GABAA receptors antagonist, showing 100-fold selectivity for α6-containing receptors over α1-containing receptors. Furosemide is a loop diuretic used in the study of congestive heart failure, hypertension, and edema. Deuterium substitution in drug molecules is explored for its potential impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter
- Acts as a GABAA receptors antagonist
- Used in the study of congestive heart failure, hypertension, and edema