Benzenesulfonic acids and derivatives
Medchemexpress LLC Acid yellow 9 monosodium salt | 74543-21-8 | 98.0% | 5 G
Acid Yellow 9 monosodium salt is an azo dye. It is degraded by Pseudomonas fluorescens as the sole source of carbon, nitrogen, and energy for the bacterium.
- Designed for high-speed applications
- 50 mL capacity
- Leak-resistant cap
- Suitable for laboratory centrifugation and storage
Medchemexpress LLC Calcium disodium edetate hydrate | 23411-34-9 | MFCD00149453 | 98.0% | 392.28 g·mol⁻¹ | C10H14CaN2Na2O9 | 5 G
Calcium disodium edetate hydrate is a chelating agent used in life-science research to sequester divalent metal ions in biochemical assays, buffer formulations, and sample preparation. It is supplied as a high-purity white to off-white solid suitable for laboratory weighing and formulation.
- High purity (98.0%) suitable for research applications.
- Effective chelation of divalent metal ions for assay and buffer stability.
- Available in small-scale packs convenient for laboratory use.
- Solid form is easy to weigh and handle for solution preparation.
- Commonly used as a reagent in analytical and preparative workflows.
Medchemexpress LLC Disodium 5'-inosinate | 4691-65-0 | 99.7% | 50 G
Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. It can bind to umami receptors and stimulate taste nerves, leading the brain to perceive umami. Additionally, Disodium 5'-inosinate causes a transient behavioral excitement in mice.
- Nucleotide-based umami agent.
- Binds to umami receptors and stimulates taste nerves.
- Produces a transient behavioral excitement in mice.
- For research use only.
Medchemexpress LLC Alkali blue 6B monos 50g
Alkali blue 6B monosodium (IND) is a basic dye that can be used as a reagent in biochemical and medical research Alkali blue 6B monosodium (IND) interacts with various proteins and can be used in protein adsorption studies Alkali blue 6B monosodium (IND) contains SO3H- NH and OH groups that may react with divalent heavy metal ions and can be used for the removal of heavy metals from aqua[1][2]
Medchemexpress LLC Cromolyn disodium | 15826-37-6 | 100.0% | 1 G
Cromolyn disodium (Cromoglycate disodium) is an orally active GSK-3β inhibitor and a mast cell stabilizer. It inhibits the release of mediators from mast cells, regulates reflex bronchoconstriction, and reduces non-specific bronchial hyperreactivity, making it useful in the research of bronchial asthma. This compound also demonstrates anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects.
- Orally active GSK-3β inhibitor
- Mast cell stabilizer
- Inhibits release of mediators from mast cells
- Regulates reflex bronchoconstriction
- Reduces non-specific bronchial hyperreactivity
- Exhibits anti-inflammatory properties
- Exhibits anti-allergic properties
- Exhibits anti-histamine properties
- Demonstrates anti-cancer effects
- Provides neuroprotective effects
Medchemexpress LLC 5-sulfosalicylic acid (dihydrate) | 5965-83-3 | 99.9% | 250 G
5-Sulfosalicylic acid dihydrate is a sulfonated salicylic acid derivative. It is effective against the breast cancer cell line, MCF-7, with less toxicity and also exhibits antioxidant activities.
- Effective against the breast cancer cell line, MCF-7, with less toxicity
- Exhibits antioxidant activities
- Reduces viability of MCF-7 cells
eMolecules 104-15-4 | 4-Toluenesulfonic acid | Ochem Incorporation172.200 | C7H8O3S | 95.000 | Cc1ccc(cc1)S(O)(=O)=O | 5g | 785215827
4-Toluenesulfonic acid | Ochem Incorporation | 104-15-4172.200 | C7H8O3S | 95.000 | Cc1ccc(cc1)S(O)(=O)=O | 5g | 785215827
Cayman Chemical 2 4-Dinitrobenzenesulfonic Ac
A hapten; induces the proliferation of primary lymphocytes and epithelial cells isolated from 2,4-DNCB-sensitized guinea pigs at 25, 50, or 100 ppm; inhibits 2,4-DNCB-induced contact sensitivity in 2,4-DNCB-sensitized guinea pigs at 600 mg/kg; has been used to induce ulcerative colitis in rats
Medchemexpress LLC QL-X-138 | 1469988-63-3 | 99.8% | 421.45 | C25H19N5O2 | 1MG
QL-X-138 is a small-molecule BTK/MNK dual kinase inhibitor that covalently binds to BTK and non-covalently to MNK. It is provided as a high-purity solid for laboratory research and has been characterized in preclinical studies for activity against hematologic malignancies and dengue virus.
- Dual inhibition of Bruton tyrosine kinase (BTK) and MAPK-interacting kinase (MNK).
- Covalent binding to BTK and non-covalent binding to MNK.
- High-purity solid form suitable for laboratory research.
- Molecular formula C25H19N5O2 and molecular weight 421.45.
- Demonstrated preclinical activity in models of lymphoma, leukemia, and dengue virus.
- For research use only; not for human or clinical use.
Medchemexpress LLC I-138 | 2098211-50-6 | C26H23F3N6O | 25 MG
I-138 is an orally active, reversible inhibitor of USP1-UAF1, with an IC50 of 4.1 nM and a Ki of 5.4 nM. It induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells. It is structurally related to ML323.
- Reversible inhibitor of USP1-UAF1
- Induces monoubiquitination of FANCD2 and PCNA in cells
- Eliminates USP1 autocleavage in cells
- Inhibits MDA-MB-436 cell viability
- Shows modest antitumor activity in mice bearing MDA-MB-436 tumors
- Can be combined with Niraparib for BRCA1/2 mutant tumor inhibition
Medchemexpress LLC I-138 | 2098211-50-6 | C26H23F3N6O | 1 MG
I-138 is an orally active, reversible inhibitor of USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM), structurally related to ML323 (HY-17543). I-138 induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells.
- Orally active and reversible inhibitor of USP1-UAF1.
- Potent inhibitory activity against USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM).
- Induces monoubiquitination of FANCD2 and PCNA in cells.
- Eliminates USP1 autocleavage in cells.
- Demonstrates modest antitumor activity in mice bearing MDA-MB-436 tumors.
- Shows enhanced inhibition of BRCA1/2 mutant tumors in vivo when combined with the PARP inhibitor Niraparib.
Medchemexpress LLC I-138 | 2098211-50-6 | C26H23F3N6O | 100 MG
I-138 is an orally active, reversible inhibitor of USP1-UAF1. It induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage. This compound is structurally related to ML323.
- Orally active and reversible inhibitor of USP1-UAF1
- Induces monoubiquitination of FANCD2 and PCNA in cells
- Eliminates USP1 autocleavage in cells
- Shows dose-dependent inhibition of MDA-MB-436 cell viability
- Exhibits modest antitumor activity in mice bearing MDA-MB-436 tumors
- Can be combined with Niraparib for BRCA1/2 mutant tumor inhibition in vivo
Medchemexpress LLC I-138 | 2098211-50-6 | C26H23F3N6O | 50 MG
I-138 is an orally active, reversible inhibitor of USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM), structurally related to ML323. It induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells.
- Eliminates USP1 self-lysis in HAP-1 USP1 WT and knockout cells
- Induces monoubiquitination of FANCD2 and PCNA in MDA-MB-436 cells
- Dose-dependently inhibits MDA-MB-436 cell viability
- Results in USP1 inhibition and modest antitumor activity in mice bearing MDA-MB-436 tumors
- Benefits BRCA1/2 mutant tumor inhibition when combined with Niraparib
eMolecules 77182-82-2 | DL-Phosphinothricin, monoammonium salt | Apollo Scientific198.159 | C5H15N2O4P | 0.000 | N.CP(O)(=O)CCC(N)C(O)=O | 1g | 562428419
DL-Phosphinothricin, monoammonium salt | Apollo Scientific | 77182-82-2198.159 | C5H15N2O4P | 0.000 | N.CP(O)(=O)CCC(N)C(O)=O | 1g | 562428419