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eMolecules 4-Bromo-2-(trifluoromethoxy)phenylacetonitrile | 1427502-10-0 | MFCD23703476 | 1g
Ambeed | 4-Bromo-2-(trifluoromethoxy)phenylacetonitrile | 1g | 600836991 | A304718 | | 1427502-10-0 | MFCD23703476 | 280.044 | C9H5BrF3NO
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eMolecules 10-(4-Bromophenyl)-9,9-dimethyl-9,10-dihydroacridine | 1342892-15-2 | MFCD29919158 | 1g
Synthonix - Stock | 10-(4-Bromophenyl)-9,9-dimethyl-9,10-dihydroacridine | 1g | 495873227 | B62893 | | 1342892-15-2 | MFCD29919158 | 364.286 | C21H18BrN
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Medchemexpress LLC Bcl-xL antagonist 2 | 1235032-75-3 | 98.86% | 10 MG
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Bcl-xL antagonist 2 is a potent, selective, and orally active antagonist of BCL-XL, exhibiting IC50 and Ki values of 0.091 μM and 65 nM, respectively. This compound promotes the apoptosis of cancer cells and is being researched for its potential applications in chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL).
- Potent and selective BCL-XL antagonist
- Orally active
- Promotes apoptosis in cancer cells
- Potential for chronic lymphocytic leukemia (CLL) research
- Potential for non-Hodgkin's lymphoma (NHL) research
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Medchemexpress LLC SSTR5 antagonist 2 h 10mg | 2988224-31-1 | 10 MG
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SSTR5 antagonist 2 hydrochloride is a research-grade hydrochloride salt that selectively antagonizes somatostatin receptor subtype 5 (SSTR5). Supplied as a white to off-white solid with high purity, it is intended for in vitro pharmacology and receptor characterization studies. Solubility and storage guidance should be followed for reproducible results.
- Selective SSTR5 antagonist for receptor pharmacology and signaling studies.
- High purity (98.85%) suitable for research applications.
- Supplied as the hydrochloride salt, solid white to off-white appearance.
- Soluble in DMSO; ultrasonic agitation recommended for full dissolution.
- Available in multiple small-scale sizes for screening and dose-response work.
- Storage recommendations provided for solid and solution stability to preserve activity.
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Medchemexpress LLC (R)-eIF4A3-IN-2 | 2095484-82-3 | 95.0% | 602.70 | C25H19Br2ClN4O2 | 10 MG
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(R)-eIF4A3-IN-2 is the R-enantiomer of eIF4A3-IN-2 and a less-active stereoisomer of a selective, noncompetitive inhibitor of eukaryotic initiation factor 4A-3 (eIF4A3). The compound is supplied as a solid and is provided with recommended storage and solubility information for laboratory handling.
- R enantiomer with reduced activity compared to the parent compound.
- Selective, noncompetitive inhibitor of eIF4A3; parent IC50 = 110 nM.
- CAS number 2095484-82-3.
- Molecular formula C25H19Br2ClN4O2 and molecular weight 602.70.
- Purity approximately 95.0% as supplied.
- Physical form: solid, white to light yellow.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solution -80°C (2 years) or -20°C (1 year).
- Solubility: soluble in DMSO (~50 mg/mL; ultrasonic assistance recommended).
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Medchemexpress LLC 4H-1-benzothiopyran-4-one, 2,3-dihydro-2-[1-(phenylmethyl)-4-piperidinyl]- | 1204401-49-9 | MFCD18206882 | 99.9% | 337.48 g/mol | C21H23NOS | 10 MG
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σ1 Receptor antagonist-1 is a potent and selective sigma-1 receptor antagonist provided as a solid research chemical for in vitro studies. It has high reported affinity for the σ1 receptor and has been used in cell-based assays to inhibit cell growth, induce apoptosis, and arrest the cell cycle. Analytical data and handling information are provided by the supplier; this compound is for research use only.
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Medchemexpress LLC (R)-eIF4A3-IN-2 | 2095484-82-3 | 602.70 | 50 MG
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(R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. It is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM. This compound targets eukaryotic initiation factor (eIF) and is involved in the cell cycle/DNA damage pathway.
- Targets eukaryotic initiation factor (eIF)
- Involved in cell cycle/DNA damage pathway
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 2 years, -20°C for 1 year
- Solubility in DMSO: 50 mg/mL (need ultrasonic)
- In vivo solubility: ≥ 2.5 mg/mL in 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline
- In vivo solubility: ≥ 2.5 mg/mL in 10% DMSO >> 90% corn oil
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Medchemexpress LLC CB1 antagonist 2 50mg | 614726-85-1 | 380.66 g/mol | C17H12Cl3N3O | 50 MG
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CB1 antagonist 2 (AM4113) is a selective cannabinoid receptor 1 (CB1) antagonist used as a research compound. It is described in patent WO2016184310A1 and is supplied as a solid or as a 10 mM solution in DMSO for in vitro and in vivo pharmacology studies.
- Selective CB1 antagonist suitable for pharmacology studies.
- Available as solid and as 10 mM solution in DMSO.
- High purity (≈99.9%).
- Provided with safety documentation and a certificate of analysis.
- Supplied in multiple small-scale sizes for preclinical research.
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Medchemexpress LLC SSTR5 antagonist 2 h 25mg | 2988224-31-1 | 25 MG
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SSTR5 antagonist 2 hydrochloride is a selective, orally active somatostatin receptor subtype 5 (SSTR5) antagonist used as a research tool for pharmacology and metabolic disease studies, including type 2 diabetes mellitus. It is provided as a hydrochloride salt in solid form and as a ready-to-use DMSO solution for in vitro and in vivo experiments.
- Selective SSTR5 antagonism for receptor-specific studies.
- Orally active in preclinical models.
- Available as solid and as 10 mM solution in DMSO.
- High purity suitable for research applications.
- Multiple pack sizes for flexible dosing and study design.
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Medchemexpress LLC Sigma-1 receptor antagonist 2 | 1639220-15-7 | 99.8% | 375.89 g/mol | C20H26ClN3O2 | 50MG
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Sigma-1 receptor antagonist 2 is a research-grade sigma-1 (σ1) receptor antagonist supplied for in vitro pharmacology and receptor binding studies. It is reported to be selective for σ1 over σ2 receptors and is provided at high purity in multiple solid quantities and as a DMSO solution for laboratory use.
- Selective for sigma-1 over sigma-2 receptor.
- High purity (99.8%).
- Available in multiple solid quantities and a 10 mM solution in DMSO.
- Molecular formula C20H26ClN3O2; molecular weight 375.89 g/mol.
- Intended for in vitro receptor binding and pharmacological studies.
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Medchemexpress LLC HY-14373 5mg Medchemexpress, CB30865 CAS:206275-15-2 Purity:>98%
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Medchemexpress, HY-14373 5mg CB30865 CAS:206275-15-2 CB30865 (ZM 242421) is a nicotinamide phosphoribosyltransferase (Nampt) inhibitor, with potent cytotoxicity. CB30865 is highly potent against a variety of human tumour cell lines (IC50 values in the 1-10 nM range). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-18009 5mg Medchemexpress, LFM-A13 CAS:244240-24-2 Purity:>98%
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Medchemexpress, HY-18009 5mg LFM-A13 CAS:244240-24-2 LFM-A13 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC50s of 2.5 μM, 10 μM and 61 μM; LFM-A13 shows no effects on JAK1 and JAK3, Src family kinase HCK, EGFR and IRK. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)- | 907952-06-1 | 99.3% | C31H26ClNO4 | 10MG
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GPR34 receptor antagonist 2 is a small-molecule antagonist of the G protein-coupled receptor GPR34 provided for preclinical research. It is intended for studies of immune and inflammatory disease mechanisms and for investigation of histamine-release modulation in mast cells.
- High purity (99.26%).
- Molecular formula C31H26ClNO4.
- Molecular weight 512.00 g/mol.
- Available as solid and as 10 mM solution in DMSO.
- Supplied in multiple milligram package sizes suitable for assay development.
- Used for immune and inflammatory disease research and histamine-release studies.
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Medchemexpress LLC CB1 antagonist 2 100mg | 614726-85-1 | 380.66 g·mol⁻¹ | C17H12Cl3N3O | 100 MG
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CB1 antagonist 2 (AM4113) is a selective cannabinoid CB1 receptor antagonist described in patent WO2016184310A1 and supplied for research use (CAS 614726-85-1). It inhibits CB1 in vivo with a reported IC50 of 25.5 nM and is provided in high-purity form for biochemical and in vivo studies.
- Selective CB1 receptor antagonist suitable for in vivo and in vitro research.
- Reported in vivo IC50 of 25.5 nM for CB1 inhibition.
- High supplied purity (99.91%).
- Available in multiple formats and sizes, including 100 mg and 10 mM solution in DMSO.
- Supplied as a characterized small-molecule research probe (CAS 614726-85-1).
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Medchemexpress LLC CE3F4 analog 1 | 2141967-43-1 | 99.7% | C11H9Br3FNO | 10MG
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CE3F4 analog 1 is a small-molecule analogue of CE3F4, a tribromo- and fluoro-substituted quinolinecarboxaldehyde used in research on Ras and GPCR/G-protein pathways. It is supplied as a solid and as DMSO solutions for biochemical and cellular studies, with stability and documentation provided for research use.
- High purity: 99.7% (manufacturer specification).
- Chemical formula C11H9Br3FNO; molecular weight 429.91 g/mol.
- Appearance: solid, white to off-white.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months).
- Available as solid masses and 10 mM solution in DMSO for assay convenience.
- SMILES: O=CN1C(C)CCC2=C1C(Br)=C(Br)C(F)=C2Br.
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