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Filtered Search Results
Medchemexpress LLC HY-111420 5mg Medchemexpress, CBP/EP300-IN-1 CAS: Purity:>98%
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Medchemexpress, HY-111420 5mg CBP/EP300-IN-1 CAS: CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC CCR2 antagonist 4 hydrochloride | 1313730-14-1 | MFCD16618399 | 99.9% | 476.32 g/mol | C21H22Cl2F3N3O2 | 10 MG
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CCR2 antagonist 4 hydrochloride is a research-grade small-molecule antagonist of the CC chemokine receptor 2 (CCR2), supplied as the hydrochloride salt for laboratory research use. It is used as a tool compound in studies of inflammation and chemotaxis. CAS 1313730-14-1; molecular formula C21H22Cl2F3N3O2; molecular weight 476.32 g/mol.
- High purity suitable for research applications.
- Provided as the hydrochloride salt for improved handling and stability.
- Intended for in vitro research and chemotaxis studies.
- Supplied in a 10 mg package.
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Medchemexpress LLC MK-2461 | 917879-39-1 | 99.3% | C24H25N5O5S | 100 MG
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MK-2461 is an ATP-competitive, selective, and orally active inhibitor of wild-type and mutant c-Met. It also inhibits Ron and Flt1, demonstrating selectivity for c-MET over other kinases. This compound can be used in the study of various cancers, such as gastric cancer.
- Inhibits phosphorylation of c-Met, AKT, and ERK1/2
- More potent against autophosphorylation of Y1349 and Y1365
- Effective against multiple c-Met mutants
- Inhibits phosphorylation of FGFR2 and PDGFR-α
- Suppresses HGF-induced cell mitogenesis
- Inhibits IL-3-independent cell growth
- Suppresses c-Met signaling and tumor growth in murine xenograft models
- Achieves up to 90% tumor growth inhibition in specific xenograft models
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eMolecules 36556-47-5 | 1-Chloro-2,3-difluorobenzene | Ambeed | MFCD04112584 | 148.540 | C6H3ClF2 | 98.000 | Fc1cccc(Cl)c1F | 1g | 525237082
1-Chloro-2,3-difluorobenzene | Ambeed | 36556-47-5 | MFCD04112584 | 148.540 | C6H3ClF2 | 98.000 | Fc1cccc(Cl)c1F | 1g | 525237082
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Selleck Chemical LLC Emedastine Difumarate
Emedastine Difumarate (Rapimine Emedastine fumarate) is the difumarate salt form of emedastine a second generation selective histamine H1 receptor antagonist with anti-allergic activity
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eMolecules 950259-82-2 | ethyl 5-(4-fluorophenyl)-1,3,4-oxadiaZole-2-carboxylate | ChemScene | MFCD14716324 | 236.202 | C11H9FN2O3 | 97.000 | CCOC(=O)c1nnc(o1)-c1ccc(F)cc1 | 100mg | 714125953
ethyl 5-(4-fluorophenyl)-1,3,4-oxadiaZole-2-carboxylate | ChemScene | 950259-82-2 | MFCD14716324 | 236.202 | C11H9FN2O3 | 97.000 | CCOC(=O)c1nnc(o1)-c1ccc(F)cc1 | 100mg | 714125953
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eMolecules 199864-86-3 | Medchem Express | RS-127445 (hydrochloride) | 5mg | 446265605 | HY-15419 | MFCD11112196 | 317.79 | C17H17ClFN3
Ambeed | 5-Fluoro-2-methoxypyridine-3-carboxaldehyde | 1g | 506391728 | A715833 | 351410-62-3 | MFCD04972398 | 155.128 | C7H6FNO2
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Medchemexpress LLC Buloxibutid (AT2 receptor agonist C21) | 477775-14-7 | MFCD26936332 | 96.8% | 475.62 | C23H29N3O4S2 | 50 MG
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Buloxibutid is a selective angiotensin II type 2 (AT2) receptor agonist (C21) used in research to study AT2-mediated GPCR signaling and related biological effects. It exhibits high affinity for AT2 and minimal activity at AT1, with manufacturer-provided data for solubility and storage to support experimental use.
- Selective AT2 receptor agonist with Ki 0.4 nM
- Markedly lower affinity for AT1 receptor (>10 μM)
- Soluble in DMSO at 50 mg/mL for in vitro applications
- In vivo formulation guidance provided with multiple solvent sequences tested
- Powder stable at -20°C for long-term storage; solution storage limits specified
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Medchemexpress LLC Not found on product page (SDS link not accessible) | 2607138-82-7 | MFCD34602688; MFCD33402167 | 99.9% | 461.79 | C19H16ClF4N3O4 | 5 MG
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ART812 is a small-molecule, orally active inhibitor of DNA polymerase theta (Polθ) with high biochemical potency (Polθ IC50 ~7.6 nM). It exhibits cellular activity in microhomology-mediated end joining (MMEJ) assays (IC50 ~240 nM) and has been investigated preclinically for targeting homologous recombination-deficient tumors and for overcoming PARP inhibitor resistance.
- High biochemical potency: Polθ IC50 ~7.6 nM
- Cellular activity in MMEJ assays (IC50 ~240 nM)
- Orally active small molecule suitable for in vivo studies
- Mechanism targets Polθ-mediated DNA repair pathways
- Investigated for synthetic-lethal targeting of HR-deficient tumors
- High reported purity (~99.9%) for research use
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Medchemexpress LLC NaV1.7 inhibitor-1 | 1494585-79-3 | 99.2% | 100 MG
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NaV1.7 inhibitor-1 is a potent research-grade small molecule inhibitor of the voltage-gated sodium channel NaV1.7, reported with sub-nanomolar potency in cellular assays. Supplied as a high-purity solid, it is intended for in vitro pharmacology and electrophysiology studies and is for research use only.
- High potency against human NaV1.7 (IC50 = 0.6 nM).
- Selective over NaV1.5 (~80-fold selectivity).
- High purity (99.17% by LCMS).
- Available in multiple pack sizes, including 100 MG solid and 10 mM DMSO solutions.
- Molecular formula C23H30FNO4S, molecular weight ~435.6 g/mol.
- Intended for laboratory research use only.
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eMolecules 389574-19-0 | PRASUGREL HCL | AstaTech | MFCD11867705 | 409.900 | C20H21ClFNO3S | 99.000 | Cl.CC(=O)Oc1cc2CN(CCc2s1)C(C(=O)C1CC1)c1ccccc1F | 1g | 248482827
PRASUGREL HCL | AstaTech | 389574-19-0 | MFCD11867705 | 409.900 | C20H21ClFNO3S | 99.000 | Cl.CC(=O)Oc1cc2CN(CCc2s1)C(C(=O)C1CC1)c1ccccc1F | 1g | 248482827
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eMolecules 352535-97-8 | 3-Bromo-2-fluorophenylboronic acid | Combi-Blocks | MFCD05664228 | 218.820 | C6H5BBrFO2 | 98.000 | OB(O)c1cccc(Br)c1F | 5g | 117523517
3-Bromo-2-fluorophenylboronic acid | Combi-Blocks | 352535-97-8 | MFCD05664228 | 218.820 | C6H5BBrFO2 | 98.000 | OB(O)c1cccc(Br)c1F | 5g | 117523517
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Enzo Life Sciences Rucaparib phosphate (100mg). CAS: 459868-92-9
Rucaparib is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
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Selleck Chemical LLC Sulindac-50mg
Sulindac(MK-231) is a non-steroidal COX inhibitor, which potently inhibits prostaglandin synthesis, used in the treatment of acute or chronic inflammatory conditions.
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Medchemexpress LLC HY-109046 10mg Medchemexpress, Tulrampator CAS:1038984-31-4 Purity:>98%
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Medchemexpress, HY-109046 10mg Tulrampator CAS:1038984-31-4 Tulrampator (CX-1632) is an orally bioavailable positive AMPAR (allosteric modulator of AMPA receptor). Antidepressant. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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