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Filtered Search Results
Medchemexpress LLC Tnf-α-in-2 | 2074702-04-6 | MFCD34471028 | 99.2% | C25H21ClF2N6O | 10MG
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TNF-α-IN-2 is a small-molecule, orally active inhibitor of tumor necrosis factor alpha for research applications. It distorts the TNFα trimer to alter signaling and reduces E-selectin expression in cellular assays.
- Potent TNFα inhibition with HTRF IC50 of 25 nM.
- Inhibits E-selectin expression in HUVECs (IC50 30 nM).
- High purity: 99.2%.
- Solid, light yellow to yellow appearance.
- Soluble in DMSO (100 mg/mL; may require sonication).
- Stable as powder at -20 °C for long-term storage.
- Available in multiple milligram pack sizes for research use only.
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eMolecules 586379-66-0 | Medchem Express | PH-797804 | 5mg | 446258469 | HY-10403 | MFCD18251426 | 477.306 | C22H19BrF2N2O3
Medchem Express | PH-797804 | 5mg | 446258469 | HY-10403 | 586379-66-0 | MFCD18251426 | 477.306 | C22H19BrF2N2O3
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eMolecules 64465-61-8 | 4-(3-Fluorophenyl)phenol | Combi-Blocks | MFCD06802291 | 188.201 | C12H9FO | 97.000 | Oc1ccc(cc1)-c1cccc(F)c1 | 1g | 117577924
4-(3-Fluorophenyl)phenol | Combi-Blocks | 64465-61-8 | MFCD06802291 | 188.201 | C12H9FO | 97.000 | Oc1ccc(cc1)-c1cccc(F)c1 | 1g | 117577924
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Medchemexpress LLC Parishin | 62499-28-9 | 996.91 | 5 MG
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Parishin is a phenolic glucoside isolated from Gastrodia elata. It exhibits antiaging effects and extends the lifespan of yeast by regulating the Sir2/Uth1/TOR signaling pathway.
- Exhibits antiaging effects.
- Extends the lifespan of yeast.
- Regulates the Sir2/Uth1/TOR signaling pathway.
- In vitro, extends the replicative lifespan of K6001 yeast at concentrations of 3, 10, and 30 μM.
- Target: Sir2/Uth1/TOR.
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eMolecules 351003-43-5 | 3,4,5-Trifluorobenzene-1-sulfonyl chloride | Ambeed | MFCD03094559 | 230.590 | C6H2ClF3O2S | 98.000 | Fc1cc(cc(F)c1F)S(Cl)(=O)=O | 1g | 595927252
3,4,5-Trifluorobenzene-1-sulfonyl chloride | Ambeed | 351003-43-5 | MFCD03094559 | 230.590 | C6H2ClF3O2S | 98.000 | Fc1cc(cc(F)c1F)S(Cl)(=O)=O | 1g | 595927252
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eMolecules 415965-35-4 | 4-Bromo-2,3,6-trifluorobenzoic acid | Apollo Scientific | MFCD06203571 | 254.990 | C7H2BrF3O2 | 95.000 | OC(=O)c1c(F)cc(Br)c(F)c1F | 1g | 562455840
4-Bromo-2,3,6-trifluorobenzoic acid | Apollo Scientific | 415965-35-4 | MFCD06203571 | 254.990 | C7H2BrF3O2 | 95.000 | OC(=O)c1c(F)cc(Br)c(F)c1F | 1g | 562455840
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Medchemexpress LLC (R)-UT-155 | 2031161-54-1 | 98.1% | 405.35 | 10 MG
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(R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. It is less active than its S-isomer. This compound is used in various research applications, particularly in cancer and urogenital disease studies.
- High purity: 98.1%
- Molecular weight: 405.35
- Solid appearance, white to off-white color
- Soluble in DMSO at 100 mg/mL
- Effective antagonist activity at human androgen receptor in HEK293 cells (IC50: 0.598 μM)
- Stable storage conditions for powder and in solvent
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![Medchemexpress LLC N-[(1R)-1-(3-cyclopentyloxyphenyl)ethyl]-3-[(2,4-dioxopyrimidin-1-yl)methoxy]propane-1-sulfonamide | 1198221-21-4 | 99.8% | 451.5 g/mol | C21H29N3O6S | 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238280.png-250.jpg)
Medchemexpress LLC N-[(1R)-1-(3-cyclopentyloxyphenyl)ethyl]-3-[(2,4-dioxopyrimidin-1-yl)methoxy]propane-1-sulfonamide | 1198221-21-4 | 99.8% | 451.5 g/mol | C21H29N3O6S | 1MG
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TAS-114 is an orally active small-molecule inhibitor that dual-targets deoxyuridine triphosphatase (dUTPase) and dihydropyrimidine dehydrogenase (DPD). It has been investigated as an adjunct to fluoropyrimidine chemotherapy to enhance efficacy by modulating nucleotide metabolism and reducing catabolism of 5-fluorouracil (CAS 1198221-21-4).
- Dual inhibition of dUTPase and DPD enhances fluoropyrimidine efficacy.
- Oral bioavailability suitable for systemic administration.
- Defined molecular formula and molecular weight support reproducible characterization.
- High reported chemical purity enables reliable experimental results.
- Appropriate for preclinical research on combination chemotherapy strategies.
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Medchemexpress LLC TRPV4 agonist-1 free 10mg | 2314467-59-7 | 10 MG
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TRPV4 agonist-1 free base is a small-molecule agonist of the transient receptor potential vanilloid 4 (TRPV4) ion channel. It activates human TRPV4 with an EC50 of 60 nM in calcium mobilization assays and is supplied for research use only.
- Activates human TRPV4 with EC50 of 60 nM in calcium mobilization assay.
- Measured by intracellular Ca2+ increase in HEK293 cells using Fura-2 AM probe.
- Molecular formula C25H22F2N4O2; molecular weight 448.46 g/mol.
- High reported purity (~99.7%).
- Available in multiple mg-scale sizes for laboratory research applications.
- Intended for laboratory research use only, not for human use.
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Medchemexpress LLC Acanthopanaxoside B | 915792-03-9 | 5 MG
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Acanthopanaxoside B is a triterpenoid saponin isolated from the leaves of Acanthopanax senticosus. This compound is typically used for research purposes.
- Isolated from Acanthopanax senticosus
- Triterpenoid saponin
- Suitable for research applications
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Medchemexpress LLC Nitroflurbiprofen 100mg | 100mg
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Nitroflurbiprofen is a cyclooxygenase (COX) inhibitor with nitric oxide (NO)-donating properties modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats
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Medchemexpress LLC HY-112125A 5mg Medchemexpress, KRN2 (bromide) CAS:1390654-28-0 Purity:>98%
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Medchemexpress, HY-112125A 5mg KRN2 (bromide) CAS:1390654-28-0 KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC SLMP53-2 | 1826116-38-4 | C26H22N2O2 | 5 MG
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SLMP53-2 is a mutant p53 reactivator that restores wild-type-like conformation and DNA-binding ability of mutp53-Y220C by enhancing its interaction with Hsp70, leading to the reestablishment of p53 transcriptional activity. It can induce cell cycle arrest, apoptosis, and endoplasmic reticulum (ER) stress, and exhibits antitumor activity.
- Restores wild-type-like function to mutant p53.
- Enhances interaction with Hsp70 to reestablish p53 transcriptional activity.
- Induces cell cycle arrest, apoptosis, and endoplasmic reticulum (ER) stress.
- Exhibits antitumor activity.
- Inhibits growth of various cancer cell lines.
- Reduces tumor volume and weight in xenograft mouse models.
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![eMolecules ChemScene / Chlorodimethyl[3-(23456-pentafluorophenyl)propyl]silane / 1g / 717420346 / CS-0214166 / 0.000 / 157499-19-9 / MFCD00054911 / 302.740 / C11H12ClF5Si](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502482562.JPG-250.jpg)
eMolecules ChemScene / Chlorodimethyl[3-(23456-pentafluorophenyl)propyl]silane / 1g / 717420346 / CS-0214166 / 0.000 / 157499-19-9 / MFCD00054911 / 302.740 / C11H12ClF5Si
ChemScene / Chlorodimethyl[3-(23456-pentafluorophenyl)propyl]silane / 1g / 717420346 / CS-0214166 / 0.000 / 157499-19-9 / MFCD00054911 / 302.740 / C11H12ClF5Si
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eMolecules 94010-78-3 | 2,2-Difluoro-2-(4-fluorophenyl)acetic acid | ChemScene | MFCD11167795 | 190.121 | C8H5F3O2 | 98.000 | OC(=O)C(F)(F)c1ccc(F)cc1 | 1g | 582648183
2,2-Difluoro-2-(4-fluorophenyl)acetic acid | ChemScene | 94010-78-3 | MFCD11167795 | 190.121 | C8H5F3O2 | 98.000 | OC(=O)C(F)(F)c1ccc(F)cc1 | 1g | 582648183
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