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Filtered Search Results
Medchemexpress LLC HY-102070 10mg Medchemexpress, NS13001 CAS:1063331-94-1 Purity:>98%
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Medchemexpress, HY-102070 10mg NS13001 CAS:1063331-94-1 NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 1-(2-pyridin-2-yl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)pyrrolo[3,2-c]pyridine | 2748337-86-0 | 99.8% | 10MG
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1-(2-pyridin-2-yl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)pyrrolo[3,2-c]pyridine | 2748337-86-0 | 99.8% | 10MG
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eMolecules 649735-63-7 | Medchem Express | Brivanib (alaninate) | 5mg | 446258089 | HY-10336 | MFCD22577162 | 441.463 | C22H24FN5O4
Medchem Express | Brivanib (alaninate) | 5mg | 446258089 | HY-10336 | 649735-63-7 | MFCD22577162 | 441.463 | C22H24FN5O4
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Medchemexpress LLC Illudin S | 1149-99-1 | MFCD00870487 | 99.8% | 264.32 | C15H20O4 | 5MG
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Illudin S is a cytotoxic natural sesquiterpene supplied for research use; it exhibits anti-tumor and antiviral activity and is reported to possess genotoxic properties, including blockage of the G1-S phase transition in human leukemia cells.
- High purity (99.8%) suitable for analytical and cellular studies.
- Supplied as a small research quantity (5 mg) in powder form.
- Solid, white to yellow appearance for straightforward handling.
- Molecular formula C15H20O4; molecular weight 264.32 g/mol.
- Documented genotoxic and cell-cycle blocking activity in vitro.
- Storage guidance: powder -20°C for long term; in solvent -80°C (short term).
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Medchemexpress LLC HY-10336 5mg Medchemexpress, Brivanib (alaninate) CAS:649735-63-7 Purity:>98%
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Medchemexpress, HY-10336 5mg Brivanib (alaninate) CAS:649735-63-7 Brivanib alaninate is an ATP-competitive inhibitor against VEGFR2 with an IC50 of 25 nM; has moderate potency against VEGFR-1 and FGFR-1, but more than 240-fold against PDGFRβ. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 885498-59-9 | METHYL 1-AMINO-4,4-DIFLUOROCYCLOHEXANECARBOXYLATE HCL | AstaTech | MFCD23703431 | 229.650 | C8H14ClF2NO2 | 95.000 | Cl.COC(=O)C1(N)CCC(F)(F)CC1 | 1g | 384830016
METHYL 1-AMINO-4,4-DIFLUOROCYCLOHEXANECARBOXYLATE HCL | AstaTech | 885498-59-9 | MFCD23703431 | 229.650 | C8H14ClF2NO2 | 95.000 | Cl.COC(=O)C1(N)CCC(F)(F)CC1 | 1g | 384830016
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Medchemexpress LLC HY-118284 10mg Medchemexpress, Vicagrel CAS:1314081-53-2 Purity:>98%
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Medchemexpress, HY-118284 10mg Vicagrel CAS:1314081-53-2 Vicagrel, an acetate derivative of Clopidogrel, is a P2Y12 platelet inhibitor potentially for the treatment of thrombosis, the substrate of carboxylesterase 2 (CES2). Vicagrel demonstrates a favorable safety profile and excellent anti-platelet activity, which could be an anti-platelet drug and for the unmet medical needs of cardiovascular diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC DSTYSLSSTLTLSK TFA | 80.4% | 1616.66 | 5 MG
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DSTYSLSSTLTLSK TFA is a human peptide designed for the quantitative detection of infliximab. It is provided as a TFA salt and exhibits a peptide content of 80.4%. This product is intended for research applications only.
- Generic human peptide
- For infliximab quantitative detection
- Provided as a TFA salt
- Peptide content of 80.4%
- For research use only
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Medchemexpress LLC CCR2 antagonist 1 | 1683534-96-4 | 98.0% | 549.47 | 10 MG
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CCR2 antagonist 1 (compound 15a) is a high-affinity and long-residence-time CCR2 antagonist, with a Ki of 2.4 nM. It is for research use only and not sold to patients.
- High-affinity CCR2 antagonist.
- Long-residence-time CCR2 antagonist.
- Ki of 2.4 nM for CCR2.
- For research use only.
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Avanti Polar Lipids TAUROHYODEOXYCHOLIC ACID 5MG
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Taurohyodeoxycholic acid, sodium salt 5mg
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eMolecules 536731-65-4 | Medchem Express | GSK-3 inhibitor 11 | 5mg | 736631181 | HY-148132 | 393.42 | C20H15N3O4S
Medchem Express | GSK-3 inhibitor 11 | 5mg | 736631181 | HY-148132 | 536731-65-4 | 393.420 | C20H15N3O4S
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Medchemexpress LLC GsMTx4 TFA | 99.9% | 4095.84 (free base) | 5 MG
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GsMTx4 TFA is a spider venom peptide designed to selectively inhibit cationic-permeable mechanosensitive channels (MSCs) within the Piezo and TRP channel families. It acts as a pharmacological tool to investigate the role of these excitatory MSCs in both normal physiological processes and various pathological conditions.
- Selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to Piezo and TRP families.
- Blocks cation-selective stretch-activated channels in various cell types.
- Attenuates lysophosphatidylcholine-induced astrocyte toxicity and microglial reactivity.
- Neuroprotective in the cerebral cortex.
- Reduces mechanical allodynia in models of inflammation and sciatic nerve injury.
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Medchemexpress LLC 5-(methylamino)-2-naphthalen-1-yl-1,3-oxazole-4-carbonitrile | 847163-28-4 | MFCD04183120 | 99.2% | 249.27 g·mol⁻¹ | C15H11N3O | 5 MG
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ML351 is a potent, selective small-molecule inhibitor of 15-lipoxygenase-1 (15-LOX-1) intended for laboratory research. It has been applied in cellular and preclinical in vivo models to probe 15-LOX-1-mediated lipid metabolism and to reduce β-cell oxidative stress. For research use only.
- Potent inhibitor of 15-LOX-1 with reported IC50 of 200 nM.
- High selectivity versus related isozymes (>250-fold), minimizing off-target activity.
- High purity (≈99.2%) suitable for biochemical and cellular assays.
- Soluble in common organic solvents and available in solid and solution formats for flexibility.
- Suitable for in vitro and in vivo research on lipid metabolism and oxidative stress pathways.
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Medchemexpress LLC HY-100991 2mg Medchemexpress, FG 7142 CAS:78538-74-6 Purity:>98%
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Medchemexpress, HY-100991 2mg FG 7142 CAS:78538-74-6 FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Cdk9-in-7 | 2369981-71-3 | 98.1% | 547.71 g·mol⁻¹ | C29H37N7O2S | 10MG
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CDK9-IN-7 is a selective, potent small-molecule inhibitor of cyclin-dependent kinase 9 (CDK9) intended for research use. It exhibits nanomolar potency (IC50 ≈ 11 nM) and has been reported to induce apoptosis and cell-cycle arrest in cancer cell models. Supplied as a powder, it is suitable for preclinical assays and mechanistic studies.
- Selective CDK9 inhibition with reported IC50 ≈ 11 nM.
- High purity approximately 98.1% suitable for research assays.
- Molecular formula C29H37N7O2S and molecular weight 547.71 g·mol⁻¹.
- Provided as a powder form, typically available in 10 mg quantity.
- Recommended storage: powder -20°C (long term) or 4°C (short term).
- Common applications include cell cycle, apoptosis, and transcriptional regulation studies.
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