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Filtered Search Results
Medchemexpress LLC HY-111412 5mg Medchemexpress, DAAO inhibitor-1 CAS:2065250-25-9 Purity:>98%
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Medchemexpress, HY-111412 5mg DAAO inhibitor-1 CAS:2065250-25-9 DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor with an IC 50 of 0.12 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 81334-34-1 | Imazapyr | Combi-Blocks, Inc. | MFCD00144470 | 261.281 | C13H15N3O3 | 98.000 | CC(C)C1(C)N=C(NC1=O)c1ncccc1C(O)=O | 25g | 603131758
Imazapyr | Combi-Blocks, Inc. | 81334-34-1 | MFCD00144470 | 261.281 | C13H15N3O3 | 98.000 | CC(C)C1(C)N=C(NC1=O)c1ncccc1C(O)=O | 25g | 603131758
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eMolecules 886762-86-3 | 4-Bromo-3-fluorobenzene-1,2-diamine | Apollo Scientific | MFCD07368683 | 205.030 | C6H6BrFN2 | 98.000 | Nc1ccc(Br)c(F)c1N | 1g | 562426483
4-Bromo-3-fluorobenzene-1,2-diamine | Apollo Scientific | 886762-86-3 | MFCD07368683 | 205.030 | C6H6BrFN2 | 98.000 | Nc1ccc(Br)c(F)c1N | 1g | 562426483
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Rieke Metals LLC 3-FLUOROBENZYL MG BR
3-Fluorobenzylmagnesium chloride, 0.25M diethyl ether
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Medchemexpress LLC HY-126534A 5mg Medchemexpress, CDK ligand for PROTAC (hydrochloride) CAS: Purity:>98%
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Medchemexpress, HY-126534A 5mg CDK ligand for PROTAC (HCl) CAS: CDK ligand for PROTAC hydrochloride is a CDK inhibitor with antitumor activity. CDK ligand for PROTAC hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC KKI-5 TFA | 99.3% | 887.90 | 10 MG
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KKI-5 TFA is a specific inhibitor of tissue kallikrein. It has been shown to attenuate breast cancer cell invasion and is intended for research use only.
- Specific inhibitor of tissue kallikrein
- Attenuates breast cancer cell invasion
- Target: Kallikrein
- For research use only
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Medchemexpress LLC N-desmethyl apalutamide | 1332391-11-3 | MFCD32858271 | 99.7% | 463.41 g/mol | C20H13F4N5O2S | 5 MG
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N-desmethyl apalutamide is the major active metabolite of apalutamide that functions as a less potent androgen receptor antagonist and a moderate-strong inducer of CYP3A4 and CYP2B6. Supplied as a white to off-white solid for research use, it is characterized by high purity and defined storage conditions.
- Active metabolite of apalutamide with androgen receptor antagonist activity.
- Moderate to strong inducer of CYP3A4 and CYP2B6.
- High purity (99.7%).
- Molecular formula C20H13F4N5O2S and molecular weight 463.41 g/mol.
- White to off-white solid suitable for analytical and pharmacology studies.
- Specified storage conditions for powder and solutions to maintain stability.
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Medchemexpress LLC Ensartinib dihydroch 100mg | 2137030-98-7 | 100MG
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Ensartinib dihydrochloride (X-396 dihydrochloride) is a potent and dual ALK/MET inhibitor with IC50s of 0 4 nM and 0 74 nM respectively
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Medchemexpress LLC AHR antagonist 5 | 2247953-39-3 | 98.1% | C25H27Cl3FN7 | 10MG
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AHR antagonist 5 is a potent, orally active aryl hydrocarbon receptor (AHR) antagonist intended for preclinical research. It demonstrates submicromolar in vitro potency and has shown in vivo activity reducing tumor growth when used with immune checkpoint inhibition. The material is supplied as a yellow-orange solid with defined solubility in DMSO and recommended cold storage conditions.
- Potent AHR antagonism with reported IC50 < 0.5 μM.
- Demonstrated in vivo efficacy in combination with anti-PD-1.
- High purity suitable for research applications.
- Soluble in DMSO at high concentrations; in vivo vehicle protocols available.
- Stable powder under recommended cold storage for long-term use.
- Available as solid and as DMSO stock solution formats.
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Medchemexpress LLC HY-107390A 5mg Medchemexpress, AX-024 hydrochloride CAS:1704801-24-0 Purity:>98%
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Medchemexpress, HY-107390A 5mg AX-024 HCl CAS:1704801-24-0 AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 3-(2-Fluorophenyl)-2H-pyrazole | 149739-32-2 | MFCD09860572 | 1g
Combi-Blocks | 3-(2-Fluorophenyl)-2H-pyrazole | 1g | 401043749 | HC-6819 | 98.000 | 149739-32-2 | MFCD09860572 | 162.167 | C9H7FN2
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Medchemexpress LLC 3α-bis-(4-fluorophenyl) methoxytropane hydrochloride | 202646-03-5 | MFCD00671778 | 100.0% | 379.87 g·mol⁻¹ | C21H24ClF2NO | 10 MG
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AHN 1-055 hydrochloride is a selective dopamine uptake inhibitor supplied as the hydrochloride salt for research use. It binds with high affinity to the dopamine transporter (DAT) and is characterized by an IC50 of 71 nM. The compound is provided as a high-purity solid suitable for biochemical and pharmacological studies.
- Selective dopamine transporter uptake inhibitor (IC50 71 nM).
- Provided as the hydrochloride salt in solid form for solution preparation.
- High purity (99.96%) appropriate for research applications.
- Available in small-scale quantities suitable for laboratory experiments.
- Useful for studies of dopamine transporter function and neuropharmacology.
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Medchemexpress LLC CMPD1 | 41179-33-3 | 99.86% | 349.40 | 50 MG
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CMPD1 is a selective and non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor with an apparent Ki (Kiapp) of 330 nM. It is for research use only and not sold to patients. This compound does not inhibit p38 MAPK-mediated phosphorylation of other two substrates, MBP and ATF2. It induces mitotic arrest and apoptosis in U87 cells, and inhibits tubulin polymerisation in glioblastoma cells.
- Antiproliferative activity against human A-172 cells assessed as cell growth inhibition (EC50 0.6 μM).
- Antiproliferative activity against human U-251 cells assessed as cell growth inhibition (EC50 0.6 μM).
- Antiproliferative activity against human U-87MG ATCC cells assessed as cell growth inhibition (EC50 0.6 μM).
- Inhibition of tubulin polymerization in human U87 cells assessed as decrease in cell viability after 72 hrs by Alamar blue assay (EC50 < 1 μM).
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Chemie Tek LY3295668(LY-3295668, AK-5MG
LY3295668 (LY-3295668, AK-01), Aurora A kinase (AurA) inhibitor with Ki of 0.8 nM, and H446 AurA auto-P IC50 of 0.6 nM, highly selective (>1000 fold) over Aurora B. LY3295668 is cytotoxic to RB1 mutant cancer cells (NCI-H446 cell IC50 = 0.752 uM), 5MG
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Medchemexpress LLC RORT INVERSE AGONIS 100 mg
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RORT INVERSE AGONIS 100MG
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