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Filtered Search Results
Medchemexpress LLC 2-((1R,5S)-8-(2-(((S)-4-(3-(N,N-dimethylsulfamoyl)-1H-pyrazole-1-carbonyl)-3-methylpiperazin-1-yl)methyl)-5-... | 3007772-60-0 | 98.1% | C27H36F3N7O5S | 10MG
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ABD957 is a potent, selective covalent inhibitor of the ABHD17 family of depalmitoylases used as a research reagent to study protein depalmitoylation and NRAS signaling in biochemical and cell-based assays. It exhibits an IC50 of 0.21 μM against ABHD17B and is supplied as a white to off-white solid.
- Potent, selective covalent inhibition of ABHD17 enzymes (IC50 0.21 μM for ABHD17B).
- Suitable for biochemical and cell-based studies of depalmitoylation and signaling.
- High purity (98.1%) for reliable experimental results.
- Available in multiple small-scale pack sizes for research use.
- Stable when stored under recommended conditions for long-term use.
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Medchemexpress LLC Dmhca | 79066-03-8 | MFCD12404996 | ≥98.0% | 401.63 g/mol | C26H43NO2 | 5 MG
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DMHCA is a selective Liver X Receptor (LXR) agonist used as a research reagent to activate the cholesterol efflux arm of LXR signaling while minimizing induction of triglyceride synthesis. It is commonly used in studies of cholesterol metabolism, lipid homeostasis, and inflammation.
- Selective LXR agonist that promotes cholesterol efflux.
- Minimal stimulation of triglyceride synthesis compared with other LXR agonists.
- Applicable to studies of cholesterol metabolism, lipid homeostasis, and inflammatory responses.
- Characterized by CAS 79066-03-8, molecular formula C26H43NO2, molecular weight 401.63 g/mol.
- Supplied in small research pack sizes suitable for in vitro studies.
- Reported purity ≥98% by HPLC from third-party suppliers.
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eMolecules 935534-49-9 | Methyl 3-bromo-2,4-difluorobenzoate | Apollo Scientific | MFCD09261258 | 251.027 | C8H5BrF2O2 | 95.000 | COC(=O)c1ccc(F)c(Br)c1F | 1g | 562436614
Methyl 3-bromo-2,4-difluorobenzoate | Apollo Scientific | 935534-49-9 | MFCD09261258 | 251.027 | C8H5BrF2O2 | 95.000 | COC(=O)c1ccc(F)c(Br)c1F | 1g | 562436614
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Medchemexpress LLC HY-10367 50mg Medchemexpress, Canertinib CAS:267243-28-7 Purity:>98%
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Medchemexpress, HY-10367 50mg Canertinib CAS:267243-28-7 Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-19366 5mg Medchemexpress, Nav1.7-IN-2 CAS:1332295-35-8 Purity:>98%
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Medchemexpress, HY-19366 5mg Nav1.7-IN-2 CAS:1332295-35-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC ONO-2952 | 895169-20-7 | 99.5% | 398.86 | 10 MG
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ONO-2952 is a potent, selective, and orally active translocator protein 18 kDa (TSPO) antagonist. It is more selective for TSPO than other receptors, transporters, ion channels, and enzymes. It exerts anti-stress effects by inhibiting excessive activation of the noradrenergic system in the brain without causing amnesic effects. This product has potential for irritable bowel syndrome treatment and is for research use only.
- Potent, selective, and orally active translocator protein 18 kDa (TSPO) antagonist with Ki of 0.33-9.30 nM for rat and human TSPO.
- More selective for TSPO than other receptors, transporters, ion channels, and enzymes.
- Exerts anti-stress effects through inhibition of excessive activation of the noradrenergic system in the brain without the amnesic effect.
- Potential for irritable bowel syndrome treatment.
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eMolecules 461-96-1 | 1-Bromo-3,5-difluorobenzene | Ambeed | MFCD00010305 | 192.991 | C6H3BrF2 | 97.000 | Fc1cc(F)cc(Br)c1 | 25g | 490556559
1-Bromo-3,5-difluorobenzene | Ambeed | 461-96-1 | MFCD00010305 | 192.991 | C6H3BrF2 | 97.000 | Fc1cc(F)cc(Br)c1 | 25g | 490556559
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Medchemexpress LLC Jnj 303 | 878489-28-2 | >98.0% | 440.98 | C21H29ClN2O4S | 10 MG
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JNJ 303 is a synthetic research compound that selectively blocks delayed-rectifier Kv (IKs) potassium currents with reported IC50 ≈ 64 nM. It is used in preclinical studies related to diabetes, obesity, and central nervous system research. The compound has molecular formula C21H29ClN2O4S and molecular weight 440.98 g·mol⁻¹.
- Potent IKs channel blocker (IC50 ≈ 64 nM).
- High purity suitable for research (>98.0% HPLC).
- Small-scale packaging for preclinical studies (1-10 mg).
- Applicable to diabetes, obesity, and central nervous system studies.
- Molecular weight 440.98 g·mol⁻¹; formula C21H29ClN2O4S.
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Medchemexpress LLC JWG-071 | 2250323-50-1 | 99.15% | 612.76 | 10 MG
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JWG-071 is a kinase-selective chemical probe for ERK5. It inhibits ERK5 and LRRK2 with IC50 values of 88 nM and 109 nM, respectively. This compound is useful for research in the MAPK/ERK pathway and Stem Cell/Wnt pathways.
- Kinase-selective chemical probe for ERK5.
- Inhibits ERK5 with an IC50 of 88 nM.
- Inhibits LRRK2 with an IC50 of 109 nM.
- Available in various solid quantities.
- High purity.
- Can be dissolved in DMSO for in vitro studies.
- Suitable for in vivo research with specific formulation recommendations.
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Medchemexpress LLC Tpa 023 Gabaa A2/A3 Subtype | HY-101640
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Tpa 023 Gabaa A2/A3 Subtype
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Medchemexpress LLC Refametinib | 923032-37-5 | MFCD18633256 | 99.8% | 572.34 g·mol⁻¹ | C19H20F3IN2O5S | 5 MG
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Refametinib is an orally active, non-ATP-competitive allosteric inhibitor of MEK1 and MEK2 used in research to modulate MAPK/ERK signaling. It exhibits low-nanomolar potency and is supplied as a high-purity solid for in vitro and preclinical studies.
- Allosteric MEK1/MEK2 inhibitor with low-nanomolar potency.
- Reported IC50: MEK1 = 19 nM; MEK2 = 47 nM.
- High purity suitable for research applications.
- Solid powder form for convenient dosing and preparation.
- Recommended storage at low temperatures to preserve stability.
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Medchemexpress LLC 1,3-Benzenedicarboxylic acid, 4-fluoro- | 327-95-7 | 99.2% | 184.12 | 100 MG
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4-Fluorobenzene-1,3-dicarboxylic acid is a chemical compound with the molecular formula C8H5FO4 and a molecular weight of 184.12. It typically appears as a white to off-white solid, exhibiting a high purity of 99.2% as determined by HPLC. This compound is suitable for various laboratory applications.
- High purity for reliable experimental results.
- Stable in powder form for extended periods at controlled temperatures.
- Suitable for various research applications requiring a fluorinated benzenedicarboxylic acid.
- Consistent with structure as confirmed by analytical testing.
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eMolecules 67500-19-0 | Ambeed | 1-(5-Amino-2-fluorophenyl)ethanone | 1g | 490516794 | A157475 | MFCD02090052 | 153.156 | C8H8FNO
Ambeed | 1-(5-Amino-2-fluorophenyl)ethanone | 1g | 490516794 | A157475 | 67500-19-0 | MFCD02090052 | 153.156 | C8H8FNO
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eMolecules 6-Bromo-2,3,4-trifluorobenzeneboronic acid | Apollo Scientific |254.800 | C6H3BBrF3O2 | 95.000 | OB(O)c1c(Br)cc(F)c(F)c1F | 1g | 562457983
6-Bromo-2,3,4-trifluorobenzeneboronic acid | Apollo Scientific |254.800 | C6H3BBrF3O2 | 95.000 | OB(O)c1c(Br)cc(F)c(F)c1F | 1g | 562457983
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Medchemexpress LLC CBP/p300-IN-8 | 2304416-91-7 | 99.9% | 461.55 | 50 MG
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CBP/p300-IN-8 is a potent inhibitor of the CBP/P300 family of bromodomains. It inhibits CBP activity with an IC50 of 0.01-0.1 μM and BRD4 activity with an IC50 of 1-1000 μM.
- Potent inhibitor of the CBP/P300 family of bromodomains.
- Inhibits CBP activity with an IC50 of 0.01-0.1 μM.
- Inhibits BRD4 activity with an IC50 of 1-1000 μM.
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