Fluorobenzenes
2-Chloro-4-fluorotoluene 98.0+%, TCI America™
CAS: 452-73-3 Molecular Formula: C7H6ClF Molecular Weight (g/mol): 144.573 MDL Number: MFCD00000572 InChI Key: CSARJIQZOSVYHA-UHFFFAOYSA-N Synonym: 2-chloro-4-fluorotoluene,benzene, 2-chloro-4-fluoro-1-methyl,4-fluoro-2-chlorotoluene,2-chlor-4-fluor-1-methylbenzol,pubchem1605,2-chloro-4fluorotoluene,acmc-1adyb,4-fluor-2-chlor-toluol,ksc235q0r,csarjiqzosvyha-uhfffaoysa PubChem CID: 96747 IUPAC Name: 2-chloro-4-fluoro-1-methylbenzene SMILES: CC1=C(C=C(C=C1)F)Cl
2,3,4-Trifluoroaniline 98.0+%, TCI America™
CAS: 3862-73-5 Molecular Formula: C6H4F3N Molecular Weight (g/mol): 147.1 MDL Number: MFCD00011737 InChI Key: WRDGNXCXTDDYBZ-UHFFFAOYSA-N Synonym: 2,3,4-trifluorobenzenamine,benzenamine, 2,3,4-trifluoro,2,3,4-trifluoraniline,2,3,4-trifluoro-phenylamine,aniline, 2,3,4-trifluoro,2,3,4-trifluoro aniline,2,3,4-trifluorophenylamine,pubchem2297,acmc-1clgf,2.3.4-trifluoroaniline PubChem CID: 77468 IUPAC Name: 2,3,4-trifluoroaniline SMILES: C1=CC(=C(C(=C1N)F)F)F
O-(2,3,4,5,6-Pentafluorobenzyl)formaldoxime 98.0+%, TCI America™
CAS: 86356-73-2 Molecular Formula: C8H4F5NO Molecular Weight (g/mol): 225.118 MDL Number: MFCD00191477 InChI Key: SRTQFRQWTUMMTC-UHFFFAOYSA-N PubChem CID: 602486 IUPAC Name: N-[(2,3,4,5,6-pentafluorophenyl)methoxy]methanimine SMILES: C=NOCC1=C(C(=C(C(=C1F)F)F)F)F
Fluconazole 98.0+%, TCI America™
CAS: 86386-73-4 Molecular Formula: C13H12F2N6O Molecular Weight (g/mol): 306.277 InChI Key: RFHAOTPXVQNOHP-UHFFFAOYSA-N Synonym: fluconazole,diflucan,triflucan,elazor,biozolene,biocanol,fungata,fluconazol,fluconazolum,flucazol PubChem CID: 3365 ChEBI: CHEBI:46081 IUPAC Name: 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol SMILES: C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O
Medchemexpress LLC GSK-3β inhibitor 3 | 1448990-73-5 | 99.2% | C18H14FNO2S | 100 MG
GSK-3β inhibitor 3 is a potent, selective, irreversible, and covalent inhibitor of Glycogen Synthase Kinase 3β (GSK-3β) with an IC50 of 6.6 μM. This compound is suitable for research related to acute promyelocytic leukemia.
- Potent, selective, irreversible, and covalent inhibitor of GSK-3β
- Inhibits GSK-3α activity by 87.3%
- Dose-dependently inhibits the growth of NB4 and NB4-R1 cells
- Significantly increases the percentage of apoptosis in NB4 and NB4-R1 cells
- Minimal cytotoxicity on human normal liver cells and human umbilical vein endothelial cells
- Inhibits tumor growth in mice by 75.97%
Medchemexpress LLC GSK-3β inhibitor 3 | 1448990-73-5 | 99.2% | C18H14FNO2S | 50 MG
GSK-3β inhibitor 3 is a potent, selective, irreversible, and covalent inhibitor of Glycogen Synthase Kinase 3β (GSK-3β), with an IC50 of 6.6 μM. It can be used for the research of acute promyelocytic leukemia.
- Potent, selective, irreversible, and covalent inhibitor of Glycogen Synthase Kinase 3β (GSK-3β)
- Has an IC50 of 6.6 μM against GSK-3β
- Used for acute promyelocytic leukemia research
- Inhibits GSK-3α activity by 87.3% (at 100 μM)
- Dose-dependently inhibits the growth of NB4 and NB4-R1 cells
- Increases apoptosis in NB4 and NB4-R1 cells
- Inhibits tumor growth in mice by 75.97% (15 mg/kg/d i.p. for 2 weeks)
- Exhibits long T1/2 of 14.2 h and high AUC values in mice
- Low cytotoxicity on human normal liver cells (LO2) and human umbilical vein endothelial cells (HUVECs)
eMolecules (1-(4-FLUOROPHENYL)CYCLOHEXYL)METHANAMINE HCL | 1279868-73-3 | MFCD22573794 | 1g
AstaTech | (1-(4-FLUOROPHENYL)CYCLOHEXYL)METHANAMINE HCL | 1g | 112526263 | 59995 | 95.000 | 1279868-73-3 | MFCD22573794 | 243.750 | C13H19ClFN
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Medchemexpress LLC GSK-3beta inhibitor 3 | 1448990-73-5 | MFCD34368538 | 99.2% | C18H14FNO2S | 10MG
GSK-3β inhibitor 3 is a covalent, irreversible small-molecule inhibitor of glycogen synthase kinase 3β used in biochemical and cellular research. It is described as potent and selective, with a reported IC50 of 6.6 μM, and is supplied as a high-purity solid suitable for mechanistic and disease-model studies.
- Covalent, irreversible inhibitor of GSK-3β for mechanistic studies.
- Reported IC50 of 6.6 μM for activity benchmarking.
- High purity (99.2%) suitable for biochemical assays and compound screening.
- Solid, white to off-white form for straightforward handling and storage.
- Available in small mg-scale quantities and as a DMSO solution for assay-ready use.
Medchemexpress LLC GSK-3β inhibitor 3 | 1448990-73-5 | 99.2% | 327.37 | C18H14FNO2S | 5 MG
GSK-3β inhibitor 3 is a potent, selective, irreversible covalent inhibitor of glycogen synthase kinase 3β (GSK-3β) intended for in vitro research applications. Reported IC50 is 6.6 μM. The compound is supplied as a solid and as a 10 mM solution in DMSO for laboratory use.
- Potent, selective inhibition of GSK-3β.
- Irreversible, covalent binding mechanism.
- Reported IC50 of 6.6 μM for biochemical assays.
- Supplied as solid and as a 10 mM solution in DMSO for convenience.
- High purity suitable for research (≈99.2%).
eMolecules Medchem Express / TG 100713 / 5mg / 533802474 / HY-13514 / / 925705-73-3 / MFCD20926347 / 254.253 / C12H10N6O
Medchem Express / TG 100713 / 5mg / 533802474 / HY-13514 / / 925705-73-3 / MFCD20926347 / 254.253 / C12H10N6O
Selleck Chemical LLC Regorafenib Hydrochloride-25mg
Regorafenib (Stivarga, BAY 73-4506) Hydrochloride is a multi-target inhibitor for VEGFR1, Murine VEGFR2/3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM, 4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.
Medchemexpress LLC HY-10331 100mg Medchemexpress, Regorafenib CAS:755037-03-7 Purity:>98%
Medchemexpress, HY-10331 100mg Regorafenib CAS:755037-03-7 Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.