Phenoxy compounds

Organic compounds that have one or more phenyl groups that are bonded to an oxygen with a radical electron; includes compounds with additional substitutions.

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1,081 – 1,095 of 2,532 results

1,081

Medchemexpress LLC Phenoxybenzamine hydrochloride | 63-92-3 | 99.5% | 1 G

Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist. It is primarily used in research for hypertension, particularly that caused by pheochromocytoma, and has also demonstrated antitumor activity.

Inhibits proliferation of U251 and U87MG cells.
Inhibits migration and invasion of U251 and U87MG cells.
Activates LINGO-1 and inhibits the TrkB-Akt pathway.
Prevents hippocampal cell death after oxygen glucose deprivation.
Demonstrates anti-tumorigenic effect in nude mice with U87MG tumors.
Exhibits neuroprotective properties in a rat model of severe traumatic brain injury.

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1,082

Medchemexpress LLC 4-Nonylphenol polyethoxylate | 26027-38-3 | 98.0% | 500 MG

4-Nonylphenol polyethoxylate (Nonoxynol) is a non-ionic surfactant primarily for research use. It forms degradation products that exhibit estrogenic activity, persist in aquatic environments, and bioaccumulate in the food chain. This product is not sold to patients.

Non-ionic surfactant
Forms degradation products including 4-nonylphenol
Exhibits estrogenic activity
Persists in aquatic environments
Bioaccumulates in the food chain

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1,083

Sigma Aldrich Fine Chemicals Biosciences (4-Bromophenoxy)-tert-butyldimethylsilane 97% | 67963-68-2 | MFCD00239382 | 5ML

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1,084

Medchemexpress LLC S-verapamil hydrochloride | 36622-28-3 | MFCD11045898 | 98.3% | C27H39ClN2O4 | 10MG

(S)-Verapamil hydrochloride is the S-enantiomer of the calcium channel blocker verapamil, supplied as the hydrochloride salt for use in pharmacology and transporter research. It is reported to inhibit leukotriene C4 (LTC4) and calcein transport by the multidrug resistance protein MRP1 and is provided as a high-purity research reagent.

Enantiomer-specific activity useful for stereoselective studies.
Suitable for transporter and pharmacology assays.
Hydrochloride salt form improves solubility in polar solvents.
Reported inhibition of LTC4 and MRP1-mediated transport.
High purity (98.3%) for reproducible experimental results.

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1,085

Medchemexpress LLC CP-466722 | 1080622-86-1 | 99.7% | 349.35 | 1 ML

CP-466722 is a rapidly reversible inhibitor of ATM (IC50 of 0.41 μM). It does not affect PI3K or related PIKK family members. This compound is for research use only. It effectively inhibits IR-induced ATM kinase activity, with this inhibition being rapid and completely reversible.

Inhibits p53 induction and ATM-dependent phosphorylation in mouse cells.
Does not inhibit ATR activity.
Disrupts ATM-dependent cell cycle checkpoints.
Completely inhibits ATM-dependent phosphorylation in MCF7 cells at 1 μM.
Reduces pKAP1 phosphorylation in MCF7 cells (IC50 of 0.41 μM at 10 μM).
Inhibits both pATM and pKAP1 signals.
Inhibits proliferation of SKBr-3 cancer cells more strongly than MCF-7.
Slightly increases proportions of MCF-7 and SKBr-3 cells in G1 phase after 48 hours.

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1,086

Medchemexpress LLC 2-(4-Chloro-phenoxy)-phenylacetic acid | 25563-04-6 | 99.6% | 262.69 | 5 G

2-(4-Chloro-phenoxy)-phenylacetic acid is a drug intermediate for the synthesis of various active compounds.

Used for the synthesis of active compounds

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1,087

Medchemexpress LLC JAK-IN-5 hydrochloride | 2751323-21-2 | 99.5% | 511.03 | 50 MG

JAK-IN-5 hydrochloride is an inhibitor of JAK, extracted from patent US20170121327A1. It is intended for research use only.

Inhibits JAK.
Inhibits STAT6 phosphorylation by 60% in IL-13-induced lung tissue in a mouse model of pSTAT6 induction at 0.5 mg/mL (oral aspirate, 50 μL).
Inhibits 88% of BALF eosinophils in a male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung at 0.1-1.0 mg/mL (oral aspirate, 50 μL).

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1,088

eMolecules 1206248-77-2 | 5-Fluorothiazolo[4,5-b]pyridin-2-amine | MFCD14581837 | 100mg

ChemScene | tert-Butyl (3-((5-bromopyrimidin-2-yl)amino)propyl)carbamate | 100mg | 768994411 | CS-0619756 | 1289003-99-1 | MFCD29113426 | 331.214 | C12H19BrN4O2

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1,089

eMolecules 2646585-67-1 | (S)-2,2-Dimethylchroman-4-amine hydrochloride | 100mg

Medchem Express | BMS-605541 | 5mg | 785215208 | HY-120640 | 639858-32-5 | 401.440 | C19H17F2N5OS

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1,090

Medchemexpress LLC Unc0224 | HY-10929

Unc0224

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1,091

Medchemexpress LLC HY-15009 5mg Medchemexpress, Fuscoside CAS:131631-89-5 Purity:>98%

Medchemexpress, HY-15009 5mg Fuscoside CAS:131631-89-5 Fuscoside (OPC-21268) is an orally effective, nonpeptide, vasopressin V1 receptor antagonist with an IC50 of 0.4 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,092

Medchemexpress LLC HY-N4277 5mg Medchemexpress, Methyl protogracillin CAS:54522-53-1 Purity:>98%

Medchemexpress, HY-N4277 5mg Methyl protogracillin CAS:54522-53-1 Methyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,093

Medchemexpress LLC HY-B0211A 50mg Medchemexpress, Riluzole hydrochloride CAS:850608-87-6 Purity:>98%

Medchemexpress, HY-B0211A 50mg Riluzole hydrochloride CAS:850608-87-6 Riluzole hydrochloride is an anticonvulsant drug and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,094

Medchemexpress LLC HY-70074 5mg Medchemexpress, CCG-63802 CAS:620112-78-9 Purity:>98%

Medchemexpress, HY-70074 5mg CCG-63802 CAS:620112-78-9 CCG-63802 is a selective, reversible and allosteric RGS4 inhibitor. CCG-63802 specifically binds to RGS4 and blocks the RGS4-Gαo interaction, with an IC50 value of 1.9 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,095

Active Motif CTPB

Active Motif's A selective activator of p300 HAT (histone acetyltransferase). Selective over PCAF (p300 CPB-associated factor).

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Phenoxy compounds

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Medchemexpress LLC Phenoxybenzamine hydrochloride | 63-92-3 | 99.5% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-Nonylphenol polyethoxylate | 26027-38-3 | 98.0% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC S-verapamil hydrochloride | 36622-28-3 | MFCD11045898 | 98.3% | C27H39ClN2O4 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CP-466722 | 1080622-86-1 | 99.7% | 349.35 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-(4-Chloro-phenoxy)-phenylacetic acid | 25563-04-6 | 99.6% | 262.69 | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC JAK-IN-5 hydrochloride | 2751323-21-2 | 99.5% | 511.03 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Unc0224 | HY-10929 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-15009 5mg Medchemexpress, Fuscoside CAS:131631-89-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-N4277 5mg Medchemexpress, Methyl protogracillin CAS:54522-53-1 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-B0211A 50mg Medchemexpress, Riluzole hydrochloride CAS:850608-87-6 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-70074 5mg Medchemexpress, CCG-63802 CAS:620112-78-9 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Active Motif CTPB Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More