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Filtered Search Results
Medchemexpress LLC Cfm 1571 hydrochloride | 1215548-30-3 | 99.5% | 444.95 g·mol⁻¹ | C23H29ClN4O3 | 5 MG
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CFM 1571 hydrochloride is a hydrochloride salt of a small-molecule soluble guanylate cyclase (sGC) stimulator used for laboratory research. It functions as a biochemical probe to study nitric oxide-cGMP signaling and sGC-mediated pathways. Supplied as a high-purity solid for in vitro and biochemical assays; not for human or animal use.
- High purity suitable for research applications.
- Hydrochloride salt for improved solubility in polar solvents.
- Used to probe sGC and nitric oxide-cGMP signaling pathways.
- Available in small pack sizes for screening and optimization studies.
- Characterized by CAS 1215548-30-3 and defined molecular formula.
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Medchemexpress LLC Rg-12525 | 120128-20-3 | 98.3% | 423.47 g/mol | C25H21N5O2 | 50 MG
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RG-12525 (NID 525) is a small-molecule research compound that antagonizes peptidoleukotriene receptors (LTC4, LTD4, LTE4), exhibits PPAR-γ agonist activity, and inhibits cytochrome P450 enzymes. It is provided in high-purity solid form and as a DMSO solution for biochemical and pharmacological research, supporting both in vitro and in vivo investigations.
- Potent leukotriene receptor antagonist with low-nanomolar activity.
- Shows PPAR-γ agonist activity (≈60 nM).
- Inhibits CYP3A4 (Ki ≈0.5 μM), useful for metabolism studies.
- Available as solid and DMSO solution for flexible dosing.
- High purity suitable for biochemical and pharmacological assays.
- Applicable to in vitro and in vivo pharmacology research.
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Selleck Chemical LLC Amuvatinib (MP-470) S1244-2mg
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Amuvatinib (MP-470 HPK 56) is a potent and multi-targeted inhibitor of c-Kit PDGFR and Flt3 with IC50 of 10 nM 40 nM and 81 nM respectively Amuvatinib suppresses c-MET and c-RET Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity Phase 2
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eMolecules 621-87-4 | Phenoxyacetone | ChemScene | MFCD00008767 | 150.177 | C9H10O2 | 98.000 | CC(=O)COc1ccccc1 | 10g | 686116656
Phenoxyacetone | ChemScene | 621-87-4 | MFCD00008767 | 150.177 | C9H10O2 | 98.000 | CC(=O)COc1ccccc1 | 10g | 686116656
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Medchemexpress LLC Hmr-1556 | 223749-46-0 | MFCD12756323 | 100.0% | 411.44 g·mol-1 | C17H24F3NO5S | 25 MG
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HMR 1556 is a chromanol-derived small molecule that selectively blocks the slow delayed rectifier potassium current (IKs) and is used as an experimental tool in cardiac electrophysiology studies. It is supplied as a high-purity research compound for in vitro ion-channel pharmacology applications.
- Potent IKs blockade with low-nanomolar IC50 values (10.5 nM in canine, 34 nM in guinea pig).
- High selectivity for IKs over other cardiac currents.
- Provided as a high-purity research-grade solid suitable for in vitro studies.
- Useful for cardiac electrophysiology and ion-channel pharmacology research.
- Available in multiple small pack sizes for research use.
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Medchemexpress LLC PND-1186 hydrochloride | 1356154-94-3 | 99.9% | C25H27ClF3N5O3 | 10MG
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PND-1186 hydrochloride is the hydrochloride salt of a potent, selective, and reversible focal adhesion kinase (FAK) inhibitor supplied for laboratory research. It exhibits nanomolar potency (IC50 = 1.5 nM) and selectively promotes tumor cell apoptosis. Supplied as a high-purity solid with defined solubility and storage recommendations for controlled experimental use.
- Potent FAK inhibition with IC50 of 1.5 nM.
- High purity (99.9%).
- Molecular formula C25H27ClF3N5O3; molecular weight 537.96.
- Soluble in DMSO (100 mg/mL) and water (20 mg/mL).
- Recommended storage: 4°C for solid; in solvent -80°C up to 6 months.
- Intended for research use only; not for human or veterinary use.
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eMolecules 588-64-7 | 1-Phenyl-2-(phenylmethylidene)hydrazine | Oakwood Chemical | MFCD00051318 | 196.253 | C13H12N2 | 96.000 | N(\N=C\c1ccccc1)c1ccccc1 | 1g | 537712504
1-Phenyl-2-(phenylmethylidene)hydrazine | Oakwood Chemical | 588-64-7 | MFCD00051318 | 196.253 | C13H12N2 | 96.000 | N(\N=C\c1ccccc1)c1ccccc1 | 1g | 537712504
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Medchemexpress LLC HY-12345 5mg Medchemexpress, ML365 CAS:947914-18-3 Purity:>98%
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Medchemexpress, HY-12345 5mg ML365 CAS:947914-18-3 ML365 is a selective inhibitor of KCNK3/TASK1 two-pore domain potassium channel, with an IC50 of 4 nM (thallium flux assay). ML365 acts as a pharmacological tool that can be used to examine the specific roles of TASK1 channels. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-B0549A 100mg Medchemexpress, Flavoxate (hydrochloride) CAS:3717-88-2 Purity:>98%
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Medchemexpress, HY-B0549A 100mg Flavoxate (hydrochloride) CAS:3717-88-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC CP-466722 | 1080622-86-1 | 99.7% | 349.35 | 1 ML
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CP-466722 is a rapidly reversible inhibitor of ATM (IC50 of 0.41 μM). It does not affect PI3K or related PIKK family members. This compound is for research use only. It effectively inhibits IR-induced ATM kinase activity, with this inhibition being rapid and completely reversible.
- Inhibits p53 induction and ATM-dependent phosphorylation in mouse cells.
- Does not inhibit ATR activity.
- Disrupts ATM-dependent cell cycle checkpoints.
- Completely inhibits ATM-dependent phosphorylation in MCF7 cells at 1 μM.
- Reduces pKAP1 phosphorylation in MCF7 cells (IC50 of 0.41 μM at 10 μM).
- Inhibits both pATM and pKAP1 signals.
- Inhibits proliferation of SKBr-3 cancer cells more strongly than MCF-7.
- Slightly increases proportions of MCF-7 and SKBr-3 cells in G1 phase after 48 hours.
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eMolecules 2366260-33-3 | Medchem Express | Tubulin inhibitor 11 | 5mg | 788478508 | HY-152156 | 409.5 | C22H23N3O3S
Medchem Express | Boc-D-norleucine | 1g | 721434795 | HY-41912B | 55674-63-0 | MFCD00063168 | 231.292 | C11H21NO4
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eMolecules 892415-28-0 | Medchem Express | EAAT2 activator 1 | 5mg | 705860901 | HY-139692 | 331.79 | C16H11ClFN3S
Medchem Express | EAAT2 activator 1 | 5mg | 705860901 | HY-139692 | 892415-28-0 | 331.790 | C16H11ClFN3S
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eMolecules 161832-65-1 | Medchem Express | Talampanel | 5mg | 446264960 | HY-15079 | MFCD00871406 | 337.379 | C19H19N3O3
ChemScene | (R)-1-(3-Methylpyridin-2-yl)ethanamine dihydrochloride | 100mg | 687357165 | CS-0197053 | 2250241-76-8 | 209.110 | C8H14Cl2N2
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Medchemexpress LLC 5-O-Methylvisammioside | 84272-85-5 | 452.45 | 100 MG
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5-O-Methylvisammioside is a natural compound isolated from *Saposhnikovia divaricata*.
- 99.90% purity
- White to off-white solid appearance
- Soluble in DMSO and H2O for in vitro use
- Compatible with various in vivo dissolution protocols
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Medchemexpress LLC Phenoxyacetone 10mM 1mL | 621-87-4 | 150.17 g/mol | C9H10O2 | 1 ML
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Phenoxyacetone is a small-molecule acetylcholinesterase (AChE) inhibitor supplied as a ready-to-use 10 mM solution in DMSO (1 mL) for in vitro research and enzymatic assays.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Suitable for in vitro acetylcholinesterase assays and biochemical screening.
- High purity reported on accompanying certificate of analysis (COA).
- Safety data sheet (SDS) and COA are available for documentation and compliance.
- Also offered as solid quantities for preparation of custom stock solutions.
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