Phenoxy compounds

Organic compounds that have one or more phenyl groups that are bonded to an oxygen with a radical electron; includes compounds with additional substitutions.

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1,216 – 1,230 of 2,738 results

1,216

Medchemexpress LLC AMG 579 | 1227067-61-9 | 99.0% | 100 MG

AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM. It is intended for research use only. In vivo, it significantly reduced PCP-induced behavior in rats over a 2-hour period with a minimum effective dose of 0.3 mg/kg, and in dogs, it exhibits a superior oral bioavailability of 72%.

Potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A)
Has an IC50 of 0.1 nM
Significantly reduces PCP-induced behavior in rats
Exhibits superior oral bioavailability in dogs (72%)
For research use only

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1,217

Medchemexpress LLC HY-107734 10mg Medchemexpress, L 152804 CAS:6508-43-6 Purity:>98%

Medchemexpress, HY-107734 10mg L 152804 CAS:6508-43-6 L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,218

eMolecules 956697-53-3 | ERISMODEGIB | AstaTech485.507 | C26H26F3N3O3 | 95.000 | C[C@H]1CN(C[C@@H](C)O1)c1ccc(NC(=O)c2cccc(c2C)-c2ccc(OC(F)(F)F)cc2)cn1 | 1g | 380297857

ERISMODEGIB | AstaTech | 956697-53-3485.507 | C26H26F3N3O3 | 95.000 | C[C@H]1CN(C[C@@H](C)O1)c1ccc(NC(=O)c2cccc(c2C)-c2ccc(OC(F)(F)F)cc2)cn1 | 1g | 380297857

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1,219

Medchemexpress LLC HY-10167A 10mg Medchemexpress, Tecalcet (Hydrochloride) CAS:177172-49-5 Purity:>98%

Medchemexpress, HY-10167A 10mg Tecalcet (HCl) CAS:177172-49-5 Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca2+[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,220

Medchemexpress LLC MCOPPB trihydrochloride | 1108147-88-1 | MFCD11840549 | 100.0% | 518.01 g·mol⁻1 | C26H43Cl3N4 | 5 MG

MCOPPB trihydrochloride is a research-grade nociceptin/orphanin FQ (NOP) receptor agonist supplied as a trihydrochloride salt. It exhibits high affinity for the human NOP receptor (pKi ≈ 10.07) and is intended for use in pharmacological studies, available in both solid and ready-to-use solution formats.

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1,221

Medchemexpress LLC HY-111940 5mg Medchemexpress, LUT014 CAS:2274819-46-2 Purity:>98%

Medchemexpress, HY-111940 5mg LUT014 CAS:2274819-46-2 LUT014 is a B-Raf inhibitor with an IC 50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,222

eMolecules 122-99-6 | 2-Phenoxyethanol | Chem-Impex | MFCD00002857 | 138.166 | C8H10O2 | 99.000 | OCCOc1ccccc1 | 1kg | 603112346

2-Phenoxyethanol | Chem-Impex | 122-99-6 | MFCD00002857 | 138.166 | C8H10O2 | 99.000 | OCCOc1ccccc1 | 1kg | 603112346

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1,223

Medchemexpress LLC N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide | 1214265-58-3 | MFCD28015100 | 98.0% | 496.99 g·mol⁻1 | C25H29ClN6O3 | 10 MG

WZ4003 is a potent, selective small-molecule inhibitor of the NUAK family kinases used as a research tool for biochemical and cellular studies. Reported activity includes an IC50 of 20 nM for NUAK1 (ARK5) and 100 nM for NUAK2, with minimal inhibition against a broad kinase panel. Supplied as solid material or as a DMSO solution for laboratory use; manufacturer-reported purity is ~98%.

Potent inhibition of NUAK1 (IC50 20 nM) and NUAK2 (IC50 100 nM).
High selectivity with negligible inhibition of approximately 139 other kinases.
Suitable for biochemical kinase assays and cellular target validation.
Available as solid (5-200 mg) and as a 10 mM solution in DMSO.
Manufacturer-reported purity approximately 98% and CAS 1214265-58-3.

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1,224

Medchemexpress LLC (rel)-Nutlin carboxylic acid | 2760669-71-2 | 50 MG

(rel)-Nutlin carboxylic acid is a Nutlin 3-based MDM2 ligand that can be connected to a ligand for protein by a linker to form PROTAC. This product has a molecular formula of C32H32Cl2N4O6 and a molecular weight of 639.53. It is intended for research use only.

Nutlin 3-based MDM2 ligand
Can be connected to a ligand for protein by a linker to form PROTAC
Targets MDM2
Targets Ligands for E3 Ligase

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1,225

Medchemexpress LLC MRK-560 | 677772-84-8 | 99.0% | C19H17ClF5NO4S2 | 50 MG

MRK-560 is an orally active, brain barrier-penetrated γ-Secretase inhibitor that acts as a chemical probe. It reduces Aβ peptide in rat brain and cerebrospinal fluid. This compound decreases mutant NOTCH1 processing by selectively inhibiting PSEN1, making it suitable for studies related to Alzheimer's disease and T-cell acute lymphoblastic leukaemia (T-ALL).

Orally active and brain barrier-penetrated
Reduces Aβ peptide in rat brain and cerebrospinal fluid
Decreases mutant NOTCH1 processing by selectively inhibiting PSEN1
Useful in studies of Alzheimer's disease
Useful in studies of T-cell acute lymphoblastic leukaemia (T-ALL)

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1,226

Medchemexpress LLC CSK-IN-1 | 2380027-49-4 | 98.6% | 50 MG

CSK-IN-1 (compound 13) is a potent, orally active c-terminal Src kinase (CSK) inhibitor with IC50 values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. It increases T cell proliferation induced by T cell receptor signaling. This product is for research use only.

Potent, orally active c-terminal Src kinase (CSK) inhibitor
Achieves IC50 values below 3 nM in CSK HTRF assay
Achieves IC50 values below 4 nM in Caliper assay
Increases T cell proliferation induced by T cell receptor signaling
Reduces inhibitory LCK phosphorylation in vivo upon oral dosing
Enhances T cell activation in response to antigen stimulation
Shows EC50 of 41 nM on ZAP70 phosphorylation in human Jurkat cells

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1,227

eMolecules 519059-04-2 | 1-(Difluoromethoxy)-4-ethynylbenzene | ChemScene | MFCD03094335 | 168.143 | C9H6F2O | 98.000 | FC(F)Oc1ccc(cc1)C#C | 100mg | 784458752

1-(Difluoromethoxy)-4-ethynylbenzene | ChemScene | 519059-04-2 | MFCD03094335 | 168.143 | C9H6F2O | 98.000 | FC(F)Oc1ccc(cc1)C#C | 100mg | 784458752

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1,228

Medchemexpress LLC N-Desmethyl Galanthamine | 41303-74-6 | 1 MG

N-Desmethyl Galanthamine (N-Norgalanthamine) is a metabolite of Galanthamine. It is an EeAChE inhibitor with an IC50 of 2.76 μM. This product can be used in the research of Alzheimer's disease.

Metabolite of Galanthamine.
EeAChE inhibitor (IC50: 2.76 μM).
Applicable in Alzheimer's disease research.
Purity: 99.60%.
Appearance: Solid, White to off-white.
Molecular weight: 273.33.
Formula: C16H19NO3.

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1,229

Apexbio Technology LLC Nimesulide 51803-78-2 100mg

Nimesulide (CAS 51803-78-2) is a non-steroidal anti-inflammatory drug (NSAID) characterized by preferential inhibition of cyclooxygenase-2 (COX-2) activity By selectively targeting COX-2 nimesulide reduces the synthesis of pro-inflammatory prostaglandins thereby exerting anti-inflammatory analgesic and antipyretic effects Due to its COX-2 selectivity nimesulide has been investigated in various models of inflammation pain and fever This compound is commonly used in preclinical and pharmacological studies to explore COX-2 mediated pathways and evaluate potential therapeutic strategies for inflammatory disorders

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1,230

Medchemexpress LLC Guaifenesin-d3 | 1189924-85-3 | 99.0% | 1 MG

Guaifenesin-d3 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. It can alleviate cough discomfort by increasing sputum volume and decreasing its viscosity, thereby promoting effective cough.

Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Derived from guaiac resin from the wood of Guajacum officinale Linné.
Helps alleviate cough discomfort by increasing sputum volume and decreasing its viscosity.
Promotes effective cough.

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Phenoxy compounds

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Medchemexpress LLC AMG 579 | 1227067-61-9 | 99.0% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-107734 10mg Medchemexpress, L 152804 CAS:6508-43-6 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10167A 10mg Medchemexpress, Tecalcet (Hydrochloride) CAS:177172-49-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MCOPPB trihydrochloride | 1108147-88-1 | MFCD11840549 | 100.0% | 518.01 g·mol⁻1 | C26H43Cl3N4 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-111940 5mg Medchemexpress, LUT014 CAS:2274819-46-2 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (rel)-Nutlin carboxylic acid | 2760669-71-2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MRK-560 | 677772-84-8 | 99.0% | C19H17ClF5NO4S2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CSK-IN-1 | 2380027-49-4 | 98.6% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-Desmethyl Galanthamine | 41303-74-6 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Nimesulide 51803-78-2 100mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Guaifenesin-d3 | 1189924-85-3 | 99.0% | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More