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Filtered Search Results
Medchemexpress LLC HY-B0549A 100mg Medchemexpress, Flavoxate (hydrochloride) CAS:3717-88-2 Purity:>98%
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Medchemexpress, HY-B0549A 100mg Flavoxate (hydrochloride) CAS:3717-88-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-19971 5mg Medchemexpress, ML239 CAS:1378872-36-6 Purity:>98%
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Medchemexpress, HY-19971 5mg ML239 CAS:1378872-36-6 ML239 is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-A0022A 100mg Medchemexpress, Azaphen (dihydrochloride monohydrate) CAS:63302-99-8 Purity:>98%
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Medchemexpress, HY-A0022A 100mg Azaphen (dihydrochloride monohydrate) CAS:63302-99-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100518 50mg Medchemexpress, T-26c CAS:869296-13-9 Purity:>98%
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Medchemexpress, HY-100518 50mg T-26c CAS:869296-13-9 T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC 50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Arn 077 (enantiomer) | 1439366-88-7 | 10MG
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Arn 077 (enantiomer) | 1439366-88-7 | 10MG
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Medchemexpress LLC HY-112610 10mg Medchemexpress, CF53 CAS:1808160-52-2 Purity:>98%
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Medchemexpress, HY-112610 10mg CF53 CAS:1808160-52-2 CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Futibatinib (TAS-120) | 1448169-71-8 | 418.45 g/mol | C22H22N6O3 | 100 MG
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Futibatinib (TAS-120) is an orally bioavailable, irreversible fibroblast growth factor receptor (FGFR) inhibitor used in research to study FGFR-driven signaling and oncology models. It inhibits FGFR1-4 and retains activity against several FGFR2 mutants, making it a tool compound for in vitro and in vivo pathway inhibition studies.
- Molecular weight: 418.45 g/mol.
- CAS number: 1448169-71-8.
- Chemical formula: C22H22N6O3.
- Target: FGFR1-4, including mutant FGFR2 variants.
- Potency: low-nanomolar IC50 values against FGFRs.
- Typical applications: biochemical assays and cellular or animal studies of FGFR signaling.
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eMolecules 3685-84-5 | 2-(Dimethylamino)ethyl 2-(4-chlorophenoxy)acetate hydrochloride | Combi-Blocks | MFCD00012533 | 294.170 | C12H17Cl2NO3 | 97.000 | Cl.CN(C)CCOC(=O)COc1ccc(Cl)cc1 | 25g | 205395705
2-(Dimethylamino)ethyl 2-(4-chlorophenoxy)acetate hydrochloride | Combi-Blocks | 3685-84-5 | MFCD00012533 | 294.170 | C12H17Cl2NO3 | 97.000 | Cl.CN(C)CCOC(=O)COc1ccc(Cl)cc1 | 25g | 205395705
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Medchemexpress LLC Apabetalone | 1044870-39-4 | 99.34% | 370.40 | 100 MG
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Apabetalone (RVX-208) is an inhibitor of BET transcriptional regulators, specifically targeting the second bromodomain (BD2) with high selectivity. It enhances the production of ApoA-I in hepatocytes, leading to an increase in high-density lipoprotein cholesterol (HDL-C). Its mechanism involves binding to bromodomains of the BET family by competing for acetylated lysine binding sites. This epigenetic modulation of ApoA-I production suggests it as a potential therapeutic agent for atherosclerosis.
- Selective BET transcriptional regulator inhibitor
- Targets the second bromodomain (BD2)
- Increases ApoA-I production in liver cells
- Elevates high-density lipoprotein cholesterol (HDL-C)
- Acts via an epigenetic mechanism
- Investigated for atherosclerosis treatment
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Medchemexpress LLC Phenoxyacetone 500mg | 621-87-4 | 150.18 g/mol | C9H10O2 | 500 MG
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Phenoxyacetone (1-phenoxy-2-propanone, CAS 621-87-4) is a small-molecule research reagent that functions as a competitive acetylcholinesterase (AChE) inhibitor. It is supplied as a light yellow liquid with high purity for laboratory use; handle and store according to recommended conditions.
- High purity (99.38%).
- Molecular formula C9H10O2, molecular weight 150.18 g/mol.
- Acts as a competitive acetylcholinesterase (AChE) inhibitor.
- Soluble in DMSO (up to 200 mg/mL; sonication may be required).
- Storage: pure form stable 3 years at -20°C and 2 years at 4°C; in solvent stable 6 months at -80°C.
- Supplied in a 500 MG package; other sizes available by request.
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eMolecules 82964-04-3 | Medchem Express | Tolrestat | 5mg | 446267450 | HY-16500 | MFCD00864170 | 357.35 | C16H14F3NO3S
Medchem Express | Tolrestat | 5mg | 446267450 | HY-16500 | 82964-04-3 | MFCD00864170 | 357.350 | C16H14F3NO3S
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eMolecules 31788-84-8 | 1-PHENYL-2-PYRROLIDINYLETHYLAMINE HCL | AstaTech | MFCD09260486 | 226.750 | C12H19ClN2 | 95.000 | Cl.NC(CN1CCCC1)c1ccccc1 | 1g | 112532361
1-PHENYL-2-PYRROLIDINYLETHYLAMINE HCL | AstaTech | 31788-84-8 | MFCD09260486 | 226.750 | C12H19ClN2 | 95.000 | Cl.NC(CN1CCCC1)c1ccccc1 | 1g | 112532361
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eMolecules 886210-16-8 | Difluorocarboxyfluorescein Cadaverine, 5-isomer | Broadpharm496.467 | C26H22F2N2O6 | 95.000 | NCCCCCNC(=O)c1ccc2c(c1)C(=O)OC21c2cc(F)c(O)cc2Oc2cc(O)c(F)cc12 | 100mg | 599128762
Difluorocarboxyfluorescein Cadaverine, 5-isomer | Broadpharm | 886210-16-8496.467 | C26H22F2N2O6 | 95.000 | NCCCCCNC(=O)c1ccc2c(c1)C(=O)OC21c2cc(F)c(O)cc2Oc2cc(O)c(F)cc12 | 100mg | 599128762
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Medchemexpress LLC 1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)-3-piperidinecarboxamide | 1207113-88-9 | 99.3% | 10 MG
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Small-molecule inhibitor of myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) signaling used in research to block MRTF-A nuclear localization and probe Rho/MKL1-SRF transcriptional pathways.
- Specific inhibitor of MRTF-A/SRF signaling for cell and molecular studies.
- High purity suitable for research applications.
- Molecular weight 478.82 g/mol; formula C21H17ClF6N2O2.
- Supplied in small mg quantities for experimental use.
- Used to study fibrosis, cytoskeletal regulation, and transcriptional pathways.
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Medchemexpress LLC MD2-TLR4-IN-1 | 2249801-12-3 | 98.2% | 100 MG
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MD2-TLR4-IN-1 is an antagonist of the myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex. It inhibits Lipopolysaccharides (LPS)-induced expression of TNF-α and IL-6 in macrophages. This product is suitable for research related to acute lung injury (ALI).
- Inhibits NF-κB in RAW264.7 macrophages
- Directly binds to the MD2-TLR4 complex and disrupts its activation
- Suppresses NF-κB p65 subunit nuclear levels in LPS-induced macrophages
- Significantly inhibits dimerization of the MD2-TLR4 complex in LPS-activated mouse primary macrophages (MPMs)
- Reduces airspace inflammation and ameliorates histopathological changes in lung tissues of LPS-challenged mice
- Decreases LPS-induced myeloperoxidase (MPO) activity and serum TNF-α levels
- Lowers mRNA levels of TNF-α, IL-6, IL-1β, IL-12, IL-33, and COX-2 in lung tissues
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