Phthalic acid and derivatives
Medchemexpress LLC Terephthalic acid-13C2 | 121191-53-5 | 99.6% | 168.12 | 1 MG
Terephthalic acid-13C2 is the 13C-labeled version of Terephthalic acid, which is an isomer and a precursor to polyester PET used in clothing and plastics. It can also be utilized to create skin tumor models. This compound is intended for research use only and is not sold to patients.
- Can be used as a tracer and as an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS.
- Contains stable heavy isotopes of carbon (13C), which are incorporated into drug molecules for quantitation during drug development.
Medchemexpress LLC Terephthalic acid | 100-21-0 | 99.99% | 166.13 | 50 G
Terephthalic acid is an isomer and a precursor of polyester PET, used in clothing and plastics. It can also be utilized to build skin tumor models and promote excessive cell proliferation by disrupting the p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway. In vivo, it can lead to bladder stone formation in animal models, particularly in weanling mice at higher doses.
- Isomer and precursor of polyester PET
- Used to build skin tumor models
- Promotes excessive cell proliferation
- Induces skin tumor formation
- Metabolized to form calcium terephthalate, potentially leading to bladder stone formation
Medchemexpress LLC Terephthalic acid (Standard) | 100-21-0 | 99.99% | 166.13 | 25 G
Terephthalic acid is an isomer and a precursor of polyester PET, used to make clothing and plastics. It can also be utilized to build skin tumor models by promoting excessive cell proliferation and disrupting the p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway. This product is for research use only.
- Used in animal modeling to create skin tumor models
- Metabolized in the body to form calcium terephthalate or calcium hydrogen terephthalate
- Promotes formation of bladder stones
- Promotes excessive cell proliferation
- Induces skin tumor formation by disrupting p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway
- Available in solid form
- Soluble in DMSO
- Stable under recommended storage conditions
- Room temperature shipping
Medchemexpress LLC Fosbretabulin disodium | 168555-66-6 | MFCD00943911 | 99.9% | 440.29 g/mol | C18H19Na2O8P | 10 MG
Fosbretabulin disodium is a water-soluble phosphate prodrug of combretastatin A4 that destabilizes microtubules and acts as a vascular-disrupting agent used in preclinical oncology research. It selectively targets tumor endothelial cells, reduces tumor blood flow, and induces central tumor necrosis; supplied as a disodium phosphate salt for laboratory use.
- Microtubule-destabilizing vascular-disruptor mechanism.
- Water-soluble disodium phosphate prodrug form.
- High purity (≈99.9%).
- Molecular weight 440.29 g/mol; formula C18H19Na2O8P.
- Available in small research quantities (1-100 mg) and 10 mM aqueous solutions.
- Intended for preclinical and in vitro research applications.
Medchemexpress LLC Adenosine, cyclic 3',5'-(hydrogen phosphate) | 60-92-4 | 99.9% | 1G
Cyclic AMP (Cyclic adenosine monophosphate), an adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. It acts as an important second messenger in many biological processes.
- Intracellular signaling molecule for cellular responses to extracellular signals.
- Modulates mediator generation.
- Suppresses expression of pro-inflammatory cytokines like TNF-α and IL-12.
- Enhances production of anti-inflammatory cytokine IL-10.
- Functions as a microbial and human endogenous metabolite.
TARGETMOL CHEMICALS INC CLOPAMIDE 50MG
Also available in 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity. purity: 98%
eMolecules 1679-64-7 | mono-Methyl terephthalate | Chem-Impex | MFCD00002557 | 180.159 | C9H8O4 | 99.000 | COC(=O)c1ccc(cc1)C(O)=O | 250g | 386903718
mono-Methyl terephthalate | Chem-Impex | 1679-64-7 | MFCD00002557 | 180.159 | C9H8O4 | 99.000 | COC(=O)c1ccc(cc1)C(O)=O | 250g | 386903718
![eMolecules 857934-89-5 | Phenyl-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methanol | Combi-Blocks | MFCD20527078 | 310.200 | C19H23BO3 | 95.000 | CC1(C)OB(OC1(C)C)c1cccc(c1)C(O)c1ccccc1 | 1g | 482935065](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502193414.JPG-250.jpg)
eMolecules 857934-89-5 | Phenyl-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methanol | Combi-Blocks | MFCD20527078 | 310.200 | C19H23BO3 | 95.000 | CC1(C)OB(OC1(C)C)c1cccc(c1)C(O)c1ccccc1 | 1g | 482935065
Phenyl-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methanol | Combi-Blocks | 857934-89-5 | MFCD20527078 | 310.200 | C19H23BO3 | 95.000 | CC1(C)OB(OC1(C)C)c1cccc(c1)C(O)c1ccccc1 | 1g | 482935065
eMolecules 1679-64-7 | MONO-METHYL TEREPHTHALATE | AstaTech | MFCD00002557 | 180.159 | C9H8O4 | 97.000 | COC(=O)c1ccc(cc1)C(O)=O | 500g | 633668235
MONO-METHYL TEREPHTHALATE | AstaTech | 1679-64-7 | MFCD00002557 | 180.159 | C9H8O4 | 97.000 | COC(=O)c1ccc(cc1)C(O)=O | 500g | 633668235
Medchemexpress LLC BIBR 1087 SE (Desethyl Dabigatran Etexilate) | 212321-78-3 | 599.68 | 10 MM * 1 ML
BIBR 1087 SE is an intermediate metabolite of dabigatran etexilate. This compound is provided as a white to yellow solid.
- For research use only
- In vitro solubility in DMSO is 250 mg/mL
- Stable as powder at -20°C for 3 years and 4°C for 2 years
- Stable in solvent at -80°C for 6 months and -20°C for 1 month
Medchemexpress LLC 8-CPT-Cyclic AMP sodium | 93882-12-3 | 99.7% | 493.79 | 25 MG
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). It is also identified as a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM. Additionally, 8-CPT-Cyclic AMP sodium inhibits PDE III and PDE IV with IC50Epac and functions as a potent Epac activator.
- Selective activator of cyclic AMP-dependent protein kinase (PKA).
- Potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM.
- Inhibits PDE III and PDE IV.
- Potent Epac activator.
- Delays TNF-/CHX-induced and α-Fas-induced apoptosis in neutrophils.
Medchemexpress LLC 5-Carboxyfluorescein diacetate N-succinimidyl ester | 150206-05-6 | 99.3% | 25 MG
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell-permeable dye that can label cells by covalently binding to intracellular molecules. It is used to track lymphocyte migration and proliferation.
- Cell permeable dye.
- Labels cells by covalently binding to intracellular molecules.
- Used to track lymphocyte migration and proliferation.
- Excitation at 482 nm.
- Emission at 525 nm.
Medchemexpress LLC Fosbretabulin disodium | 168555-66-6 | 99.9% | 440.29 | 25 MG
Fosbretabulin disodium is a tubulin destabilizing agent and a Combretastatin A4 proagent. It selectively targets endothelial cells, inducing the regression of nascent tumor neovessels, reducing tumor blood flow, and causing central tumor necrosis. This agent is intended for research use only.
- Acts as a tubulin destabilizing agent
- Functions as a Combretastatin A4 proagent
- Selectively targets endothelial cells
- Induces regression of nascent tumor neovessels
- Reduces tumor blood flow
- Causes central tumor necrosis
- Inhibits growth of various cell lines in vitro
- Increases mean arterial blood pressure and reduces heart rate in vivo
- Reduces tumor blood flow in vivo