Sulfanilides
Medchemexpress LLC (R)-Bay-899 | 2988191-40-6 | 99.9% | C25H19F2N5O2 | 10MG
(R)-BAY-899 is the R-enantiomer of an orally active, selective luteinizing hormone receptor (LH-R) antagonist supplied for research use. Provided as an off-white to light yellow solid with high reported purity and defined molecular properties, it is intended for biochemical and pharmacological studies including receptor pharmacology and in vitro assays.
- High purity: 99.9%.
- Molecular formula: C25H19F2N5O2.
- Molecular weight: 459.45 g/mol.
- CAS registry number: 2988191-40-6.
- Off-white to light yellow solid appearance.
- Reported activity against LH receptor with IC50s of 185 nM (human) and 46 nM (rat).
- For research use only; not for human therapeutic use.
Medchemexpress LLC Bay-899 | 2471967-92-5 | 99.9% | C25H19F2N5O2 | 10MG
BAY-899 is a tetrahydro-1,6-naphthyridine-based small-molecule antagonist of the luteinizing hormone receptor (LH-R), used as a research probe to modulate LH-R signaling and reduce sex hormone levels in vitro and in vivo.
- Orally active small molecule with demonstrated in vivo activity.
- Selective LH-R antagonism with IC50s: human 185 nM, rat 46 nM.
- High chemical purity (99.9%) suitable for biochemical assays.
- Molecular formula C25H19F2N5O2; molecular weight 459.45 g·mol⁻¹.
- Supplied as a solid for solution preparation and dosing studies.
Medchemexpress LLC Sbi-477 | 781628-99-7 | MFCD04508832 | 98.0% | 483.54 | C24H25N3O6S | 5MG
SBI-477 is a small-molecule chemical probe that deactivates the transcription factor MondoA, stimulating insulin signaling and reducing expression of insulin-pathway suppressors such as TXNIP. It is supplied as a purified solid intended for research use and is characterized by molecular weight 483.54 and formula C24H25N3O6S.
- Deactivates MondoA to stimulate insulin signaling.
- Used in cellular studies to modulate glucose uptake and lipid synthesis.
- Purity 98.0%.
- Molecular weight 483.54 g/mol.
- Chemical formula C24H25N3O6S.
- Soluble in DMSO (≈65 mg/mL); hygroscopic-use fresh DMSO and ultrasonic assistance if needed.
- Store powder at -20°C for long-term stability; follow solvent storage recommendations for solutions.
![Medchemexpress LLC N-[3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide | 1622902-68-4 | MFCD30187577 | 99.3% | 323.41 g·mol⁻¹ | C14H21N5O2S | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239757.png-250.jpg)
Medchemexpress LLC N-[3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide | 1622902-68-4 | MFCD30187577 | 99.3% | 323.41 g·mol⁻¹ | C14H21N5O2S | 50 MG
Abrocitinib is a selective, orally active JAK1 inhibitor supplied as a research-grade reference standard for biochemical and cellular assays targeting the JAK/STAT pathway. It demonstrates potent inhibition of JAK1 and reduced activity against JAK2, and is intended for laboratory research use only (not for human or veterinary use).
- Selective JAK1 inhibition with reported IC50 of 29 nM.
- Reduced JAK2 activity (IC50 ≈ 803 nM).
- High purity suitable for reference and assay use (purity 99.3%).
- Molecular formula C14H21N5O2S; molecular weight 323.41 g·mol⁻¹.
- Supplied for biochemical and cellular research applications.
- Available in multiple package sizes, including 50 mg.
Medchemexpress LLC Litronesib racemate | 546111-97-1 | 99.2% | 511.70 g·mol⁻¹ | C23H37N5O4S2 | 10 MG
Litronesib racemate is the racemic form of litronesib, a selective, mitosis-specific allosteric inhibitor of the kinesin Eg5 motor protein. It is supplied as a high-purity research reagent with supporting documentation for preclinical studies.
- High purity (99.2%).
- Selective mitosis-specific Eg5 inhibitor.
- Molecular weight 511.70 g·mol⁻¹.
- Chemical formula C23H37N5O4S2.
- Available in milligram pack sizes for research use.
- Includes data sheet, COA, and SDS.
- For research use only; not for human or veterinary use.
Medchemexpress LLC N-(cis-3-(methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)cyclobutyl)-1-propanesulfonamide | 1622902-68-4 | MFCD30187577 | >98.0% | 323.41 | C14H21N5O2S | 100 MG
Abrocitinib is a potent, orally active, and selective JAK1 inhibitor supplied as a research-grade analytical standard. It is provided as a purified solid suitable for in vitro pharmacology, assay development, and analytical reference. Chemical identity: N-(cis-3-(methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)cyclobutyl)-1-propanesulfonamide; CAS 1622902-68-4; formula C14H21N5O2S; molecular weight 323.41 g/mol.
- Potent, selective JAK1 inhibitor for mechanistic and screening studies.
- High purity (>98.0%) suitable for analytical and assay use.
- Solid powder form for accurate weighing and formulation.
- Well-characterized chemical identity with CAS 1622902-68-4.
- Appropriate for in vitro pharmacology and compound profiling.
Medchemexpress LLC (R)-BAY-899 | 2988191-40-6 | 99.9% | 50 MG
(R)-BAY-899 is the R-enantiomer of BAY-899, an orally active and selective luteinizing hormone receptor (LH-R) antagonist. It exhibits IC50s of 185 nM for human LH and 46 nM for rat LH.
- Selective luteinizing hormone receptor antagonist
- Orally active
- IC50s: 185 nM for hLH, 46 nM for rLH
- Molecular weight: 459.45
- Chemical formula: C25H19F2N5O2
- Appearance: Off-white to light yellow solid
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- Solubility in DMSO: 125 mg/mL (272.06 mM)
- Solubility (in vivo): ≥ 5 mg/mL in various protocols