Aminophenols
Medchemexpress LLC Sotalol hydrochloride | 959-24-0 | 99.9% | 50 MG
Sotalol hydrochloride is an orally active, non-selective β-adrenergic receptor blocker. It functions as a potent antiarrhythmic agent suitable for research on pediatric arrhythmias. It blocks β-receptors and potassium KCNH2 channels, and is also identified as an Antiepileptic Agent.
- Orally active
- Non-selective β-adrenergic receptor blocker
- Potent antiarrhythmic agent
- Blocks β-receptors and potassium KCNH2 channels
- Antiepileptic agent
- In vivo effects up to 100 mg/kg do not impact electroconvulsive threshold
- Does not interfere with antielectroshock action of several antiepileptic drugs at 80-100 mg/kg
- Does not impair motor performance or long-term memory when used alone or in combination with antiepileptics
Cayman Chemical NGaminoLArginine hydrochlori
Inhibits nNOS, iNOS, and eNOS (Ki = 0.3, 3, and 2.5 μM, respectively); can be used both in cell culture and in vivo
Medchemexpress LLC HLCL-61 hydrochloride | 1158279-20-9 | MFCD09446681 | 99.9% | 380.91 g/mol | C23H25ClN2O | 1 ML
HLCL-61 hydrochloride is a small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) supplied for research use. It is provided as concentrated DMSO stock solutions and as solid material for in vitro and in vivo studies; not for human or veterinary use.
- First-in-class PRMT5 inhibitor for research applications.
- Available as 10 mM stock solutions in DMSO and as solids in multiple sizes.
- High reported purity (approximately 99.9%).
- Soluble in DMSO (≈131 mM at 50 mg/mL) and poorly soluble in water.
- Storage: sealed at 4°C for solids; in solvent -80°C for long-term storage.
- Identifying information: CAS number 1158279-20-9; molecular weight ≈380.91 g/mol.
Medchemexpress LLC MT-7716 hydrochloride | 1215859-93-0 | 99.1% | 477.00 g/mol | C27H29ClN4O2 | 5 MG
MT-7716 hydrochloride is the hydrochloride salt of a selective, non-peptide nociceptin (NOP) receptor agonist used in preclinical pharmacology research. It is provided as a high-purity solid for use in in vitro assays and in vivo studies investigating alcohol abuse and relapse prevention.
- High purity solid suitable for research applications.
- Soluble in DMSO at ≥ 100 mg/mL for in vitro use.
- Manufacturer-recommended in vivo formulations available for dosing.
- Storage: 4°C sealed; in solvent store at -80°C (6 months) or -20°C (1 month).
- Molecular weight 477.00 g/mol; molecular formula C27H29ClN4O2.
Medchemexpress LLC SKI-178 | 1259484-97-3 | 99.3% | 10 MG
SKI-178 is a potent inhibitor of both sphingosine kinase-1 (SphK1) and SphK2. It exhibits cytotoxicity at IC50 concentrations ranging from 0.1 to 1.8 μM in various cancer cell lines, including those resistant to multiple agents. This compound has been shown to induce apoptosis in human acute myeloid leukemia cell lines through a CDK1-dependent mechanism.
- Potent sphingosine kinase-1 and SphK2 inhibitor
- Exhibits cytotoxicity in various cancer cell lines
- Induces apoptosis in a CDK1-dependent manner
- Inhibits leukemic progression in an MLL-AF9 mouse model
- Suitable for in vitro and in vivo studies
Medchemexpress LLC Ly294002 (hydrochloride) | 934389-88-5 | MFCD00270881 | 99.9% | 343.80 g/mol | C19H18ClNO3 | 100 MG
LY294002 hydrochloride is the hydrochloride salt of LY294002, a broad-spectrum phosphoinositide 3-kinase (PI3K) inhibitor that also shows activity against CK2 and DNA-PK. Supplied for research use in powder and solution formats, it is used to probe PI3K signaling, apoptosis, and related kinase pathways. CAS 934389-88-5; molecular weight 343.80 g/mol; high purity suitable for biochemical and cell-based assays.
- Potent PI3K inhibitor useful for signaling studies.
- Also inhibits CK2 and DNA-PK, enabling broader kinase pathway interrogation.
- Available as powder and as DMSO solution for flexible dosing.
- High purity suitable for biochemical and cell-based assays.
- Stable when stored sealed at 4°C, away from moisture.
- Widely used in oncology and cell signaling research applications.
Medchemexpress LLC GSK 690 Hydrochlorid 10mM 1mL | 2436760-79-9 | 405.92 | C24H24ClN3O | 1 ML
GSK 690 Hydrochloride is a reversible inhibitor of lysine-specific demethylase 1 (LSD1) with reported Kd 9 nM and biochemical IC50 37 nM. It is supplied for research use in solution and solid formats and is characterized by high purity suitable for biochemical assays.
- Reversible LSD1 inhibitor with Kd 9 nM and IC50 37 nM.
- Supplied as 10 mM solution in DMSO (1 mL) and as solid quantities.
- High purity (98.58%) suitable for biochemical and cell-based studies.
- Molecular weight 405.92 and formula C24H24ClN3O.
- Storage: sealed at 4°C; in solvent: -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC 3-(benzyl(isopropyl)amino)-1-(naphthalen-2-yl)propan-1-one hydrochloride | 1021868-92-7 | MFCD04974534 | >98.0% | 367.91 g/mol | C23H26ClNO | 10MM 1ML
ZM39923 hydrochloride is a small-molecule JAK3 inhibitor used in research. It displays JAK3 potency (pIC50 = 7.1) and also inhibits tissue transglutaminase (TGM2) with an IC50 of 10 nM; it is supplied as a 10 mM solution in DMSO and in solid quantities.
- Small-molecule JAK3 inhibitor (pIC50 = 7.1).
- Potent TGM2 inhibition (IC50 = 10 nM).
- Available as 10 mM solution in DMSO and in solid forms.
- Molecular formula C23H26ClNO.
- Molecular weight 367.91 g/mol.
- Purity >98.0% by HPLC.
- For research use only.
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 50 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. This compound demonstrates broad antiviral activities against Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. It is suitable for research related to infection.
- Selective inhibitor of CDK7
- Inhibits human cytomegalovirus (HCMV) replication
- Broad antiviral activities against various viruses
- Suitable for infection research
- Exhibits anti-proliferative activity in human fibroblasts
- Demonstrates good oral bioavailability and half-life in vivo
Medchemexpress LLC Mepazine hydrochloride | 2975-36-2 | 99.3% | 5 MG
Mepazine hydrochloride is the hydrochloride salt of mepazine, supplied for research use as a solid or as a DMSO solution and intended for in vitro biochemical and cellular assays.
- High purity (99.25%).
- Molecular formula C19H23ClN2S.
- Molecular weight 346.92 g/mol.
- Available in small solid packs and a 10 mM DMSO solution format.
- Store sealed at 4°C; in solution, store at -80°C for long-term stability.
Medchemexpress LLC CBL0137 hydrochloride | 1197397-89-9 | 99.7% | 372.89 g/mol | C21H25ClN2O2 | 10 MG
CBL0137 hydrochloride is a research-grade small molecule that inhibits the histone chaperone FACT, activates p53, and suppresses NF-κB signaling. It is used in preclinical studies to probe chromatin regulation and anticancer mechanisms in cell-based and biochemical assays.
- Inhibits the histone chaperone FACT.
- Activates p53 in cell-based assays (IC50 ≈ 0.37 μM).
- Inhibits NF-κB signaling in cell-based assays (IC50 ≈ 0.47 μM).
- High chemical purity, typically reported as 99.7%.
- Available as solid packs and as a DMSO solution for in vitro use.
- Suitable for mechanistic studies, pathway modulation, and preclinical cancer research.
Cambridge Isotope Laboratories 4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
Medchemexpress LLC CWI1-2 hydrochloride | 2408590-37-2 | C22H18Cl4N6O3 | 1 ML
CWI1-2 hydrochloride | 2408590-37-2 | C22H18Cl4N6O3 | 1 ML