Aminophenols
Medchemexpress LLC R 59-022 (hydrochloride) | 93076-98-3 | MFCD34676749 | 98.9% | 496.04 | C27H27ClFN3OS | 5 MG
R 59-022 (hydrochloride) is a research-grade small-molecule inhibitor used to probe diacylglycerol kinase (DGK) activity and downstream lipid signaling pathways in biochemical and cellular studies. The compound is supplied as a hydrochloride salt with reported molecular weight 496.04 and high analytical purity appropriate for laboratory research applications.
- Selective diacylglycerol kinase inhibitor activity.
- Potentiates protein kinase C activation in cellular assays.
- High purity suitable for biochemical and cell-based studies.
- Supplied as a hydrochloride salt to aid solubility in polar solvents.
- Provided in small research pack sizes for laboratory use.
Medchemexpress LLC Guvacine hydrochloride | 6027-91-4 | MFCD00055191 | 99.9% | 163.60 g/mol | C6H10ClNO2 | 25 MG
Guvacine hydrochloride is the hydrochloride salt of guvacine, a pyridine alkaloid that acts as a GABA uptake inhibitor. Supplied as a high-purity research reagent, it is used in biochemical and neuropharmacological studies to probe GABA transporter activity. The substance is intended for laboratory research use only and is not for human or veterinary use.
- High purity (99.93%) for reliable experimental results.
- Molecular weight 163.60 g/mol.
- Molecular formula C6H10ClNO2.
- CAS number 6027-91-4 for unambiguous identification.
- Available in multiple pack sizes and solution formats for flexible use.
- Suitable for in vitro biochemical and pharmacology research.
Medchemexpress LLC Bi-9627 (hydrochloride) | 1422252-46-7 | 98.01% | 392.80 | 1 ML
BI-9627 hydrochloride is a potent inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1), exhibiting high selectivity over NHE2 and no measurable activity against NHE3. This compound shows low agent-agent interaction potential, excellent pharmacokinetics, and potent activity in isolated heart models of ischemia-reperfusion injury. It is intended for research use only.
- Decreases autophagy in HTR-8/SVneo cells.
- Significantly reduces the pHi of human sperm and partially reverses the effect of DMA.
- Prolongs Ca2+ recovery time in KO hiPSC-CMs.
- Shows low DDI potential.
- Excellent pharmacokinetics in rat and dog.
- Potent activity in isolated heart models of ischemia-reperfusion injury.
Medchemexpress LLC His-pro (hydrochloride) | 2415727-78-3 | 99.8% | 288.73 | 10 MG
His-Pro hydrochloride, also known as Histidyl-proline hydrochloride, is a dipeptide composed of histidyl and proline. This compound is commonly used in laboratory research.
- Dipeptide
- Solid appearance
- White to off-white color
Medchemexpress LLC AZD9056 hydrochloride | 345303-91-5 | MFCD30533694 | 98.2% | 455.46 | 1 ML
AZD9056 hydrochloride is a selective, orally active inhibitor of P2X7, a receptor involved in inflammation and pain-causing diseases. It is for research use only.
- Selectively inhibits P2X7 receptors.
- Exhibits pain-relieving and anti-inflammatory effects.
- Blocks P2X7 receptors with an IC50 of 11.2 nM in HEK-hP2X7 cell line.
- Shows inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells.
- Reverses upregulated expression of IL-1β, IL-6, TNF-α, MMP-13, SP, and PGE2 induced by MIA in cartilage tissues.
- Investigated in clinical trials for conditions like rheumatoid arthritis.
Medchemexpress LLC Delapril (hydrochloride) | 83435-67-0 | MFCD00884619 | 98.0% | 489.00 g·mol⁻¹ | C26H33ClN2O5 | 100 MG
Delapril hydrochloride is the hydrochloride salt of delapril, a lipophilic angiotensin-converting enzyme (ACE) inhibitor used in preclinical research on hypertension and cardiovascular pharmacology. The compound is supplied as a solid research reagent with confirmed identity and analytical data.
- Research reagent for ACE inhibition and cardiovascular studies.
- CAS number 83435-67-0.
- Molecular formula C26H33ClN2O5; molecular weight 489.00 g·mol⁻¹.
- Purity 98.0% (NMR) as stated on COA.
- Physical appearance solid.
- Recommended storage 4°C; in solvent -80°C for 6 months, -20°C for 1 month (sealed).
- Packaged as 100 mg research quantity.
Medchemexpress LLC Metixene hydrochloride hydrate | 7081-40-5 | ≥95.0% | 5MG
Metixene hydrochloride hydrate | 7081-40-5 | ≥95.0% | 5MG
Medchemexpress LLC L-NAME hydrochloride (NG-Nitroarginine methyl ester hydrochloride) | 51298-62-5 | 99.9% | 269.69 | 500 MG
L-NAME hydrochloride is a nitric oxide synthase (NOS) inhibitor with an IC50 of 70 μM. It acts as a precursor to the more potent NOS inhibitor L-NOARG (IC50 of 1.4 μM), making it valuable in studies of L-arginine analogues that inhibit NOS activity. Its efficacy can increase with prolonged incubation at neutral or alkaline pH, correlating with its hydrolysis to L-NOARG. This compound is also used to induce hypertension and preeclampsia models in animal studies.
- Inhibits NOS with an IC50 of 70 μM.
- Precursor to NOS inhibitor L-NOARG.
- Used to induce hypertension and preeclampsia models in animal studies.
- Appearance: solid, white to off-white.
- Storage: -20°C, sealed, away from moisture.
- In solvent: -80°C for 6 months; -20°C for 1 month.
