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Aminophenols

Organic compounds that consist of a phenol ring with an amino functional group substitution; amino functional groups consist of a nitrogen atom bonded to hydrogen atoms via single bonds.
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Search Within Results
Keyword Search:
286 – 300 of 1,069 results
286

Medchemexpress LLC dAURK-4 (hydrochloride) | 99.4% | 1071.93 | 100 MG
SDP

dAURK-4 hydrochloride is a potent and selective PROTAC AURKA (Aurora A) degrader. This derivative of Alisertib exhibits anticancer effects and is composed of a ligand for target protein, a linker, and a ligand for E3 ligase.

  • Potent and selective degrader of AURKA (Aurora A)
  • Exhibits anticancer effects
  • Degrades AURKA in a dose-dependent manner (125-1000 nM; 4-24 hours)
  • Inhibits protein level of AURKA (Aurora A) in MM.1S cells

ENCOMPASS_PREFERRED
287

Medchemexpress LLC BI-9627 hydrochloride | 1422252-46-7 | 98.0% | 392.80 | 25 MG
SDP

BI-9627 hydrochloride is a potent and selective sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor, with IC50 values of 6 nM and 31 nM. It demonstrates high selectivity over other NHE isoforms and has shown effects on autophagy, pH regulation, and Ca2+ recovery in various cell types. This compound exhibits favorable pharmacokinetic properties and cardioprotective activity. For research use only.

  • Potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor (IC50 = 6 and 31 nM).
  • High selectivity (>30-fold) against NHE2; no activity against NHE3.
  • Decreases autophagy in HTR-8/SVneo cells.
  • Reduces pHi of human sperm and partially reverses DMA effect.
  • Prolongs Ca2+ recovery time in KO hiPSC-CMs.
  • Low drug-drug interaction (DDI) potential.
  • Excellent pharmacokinetics in rat and dog.
  • Potent activity in isolated heart model of ischemia-reperfusion injury.

ENCOMPASS_PREFERRED
288

eMolecules​ 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 1mg | 564356411

Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 1mg | 564356411

ENCOMPASS_PREFERRED
289

Medchemexpress LLC 4-Piperidinecarboxamide, N-hydroxy-1-(2-methoxyethyl)-4-[[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl]-, hydrochloride (1:1) | 226395-93-3 | 99.4% | 554.96 | 10 MG
SDP

SD-2590 hydrochloride is a potent MMP inhibitor with IC50 values of <0.1, <0.1, 0.18, and 1.7 nM for MMP2, MMP13, MMP9, and MMP8, respectively. It inhibits dilation of the left ventricle in rats. This product is for research use only.

  • Potent MMP inhibitor
  • Inhibits dilation of the left ventricle in rats
  • Solid appearance
  • White to off-white color
  • Ships at room temperature
  • Store at -20°C, sealed, away from moisture
  • Soluble in DMSO at 55.5 mg/mL

ENCOMPASS_PREFERRED
290

Medchemexpress LLC RGX-104 (hydrochloride) | 610318-03-1 | 99.9% | 632.54 | 10 MG
SDP

RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. It is for research use only and not sold to patients.

  • LXR agonist
  • Modulates innate immunity via transcriptional activation of the ApoE gene
  • Oral administration significantly suppresses the growth of multiple cancer types (e.g., lung cancer, melanoma, glioblastoma, ovarian, renal cell, triple-negative breast, and colon cancer) in animals with palpable tumors.
  • Can cause partial or complete tumor regression in some instances.

ENCOMPASS_PREFERRED
291

Medchemexpress LLC BN82002 hydrochloride | 1049740-43-3 | 99.4% | 395.88 | 50 MG
SDP

BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. The compound demonstrates approximately 20-fold greater selectivity over CD45 tyrosine phosphatase and inhibits cell proliferation in several human tumor cell lines in a concentration-dependent manner in the low micromolar range. Treatment with 50 μM BN82002 modestly affects cell cycle distribution, suggesting cell cycle arrest at various stages.

  • Potent, selective, and irreversible inhibitor of CDC25 phosphatase family.
  • Displays approximately 20-fold greater selectivity over CD45 tyrosine phosphatase.
  • Inhibits cell proliferation in various human tumor cell lines.
  • For research use only.

ENCOMPASS_PREFERRED
292

Medchemexpress LLC Sotalol hydrochloride | 959-24-0 | 99.9% | 100 MG
SDP

Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker and a potent antiarrhythmic agent. It can be used for the research of pediatric arrhythmias and also functions as an antiepileptic agent.

  • Blocks β-receptors
  • Blocks potassium KCNH2 channels
  • Suitable for research on pediatric arrhythmias
  • Functions as an antiepileptic agent

ENCOMPASS_PREFERRED
293

Medchemexpress LLC Bestatin-d7 (hydrochloride) | 97.7% | 1 MG
SDP

Bestatin-d7 (hydrochloride) is a deuterium-labeled version of Bestatin (hydrochloride). Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, primarily utilized in cancer research.

  • Deuterium labeled compound
  • Can be used as a tracer
  • Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
  • Inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase

ENCOMPASS_PREFERRED
294

Medchemexpress LLC SAR7334 hydrochloride | 1333207-63-8 | 98.0% | 440.79 g/mol | C21H24Cl3N3O | 10 MG
SDP

SAR7334 hydrochloride is the hydrochloride salt of SAR7334, a potent and selective small-molecule inhibitor of the TRPC6 ion channel. It inhibits TRPC6 currents with an IC50 of 7.9 nM and is supplied as a high-purity research reagent for biochemical and cellular studies.

  • Potent TRPC6 inhibitor (IC50 7.9 nM).
  • Hydrochloride salt form for improved stability and solubility.
  • Purity: 98.0% (as supplied).
  • Molecular weight: 440.79 g/mol.
  • Available as milligram quantities and as a 10 mM solution in DMSO.
  • Intended for research use only; not for human or clinical use.

ENCOMPASS_PREFERRED
295

Medchemexpress LLC PKI-179 hydrochloride | 1463510-35-1 | 99.66% | 525.00 | 10 MG
SDP

PKI-179 hydrochloride is a potent and orally active dual PI3K/mTOR inhibitor. It exhibits activity over various PI3K isoforms and mTOR, along with E545K and H1047R. This compound demonstrates anti-tumor activity in vivo.

  • Potent and orally active dual PI3K/mTOR inhibitor
  • Inhibits PI3K-α, PI3K-β, PI3K-γ, PI3K-δ and mTOR
  • Shows activity over E545K and H1047R
  • Exhibits anti-tumor activity in vivo

ENCOMPASS_PREFERRED
296

Medchemexpress LLC Sotalol hydrochloride | 959-24-0 | MFCD00242937 | 99.9% | 308.82 g/mol | C12H21ClN2O3S | 10 MG
SDP

Sotalol hydrochloride is an orally active, non-selective β-adrenergic receptor blocker with class III antiarrhythmic activity used in cardiovascular and electrophysiology research. It is supplied as a characterized research chemical with high purity and documented analytical data.

  • High purity as determined by LCMS (≈99.9%).
  • Molecular weight 308.82 g/mol and molecular formula C12H21ClN2O3S.
  • Used to study β-receptor blockade and cardiac repolarization (potassium channel) effects.
  • Supplied in small research pack sizes and solution formats (for example, 10 MG solid or 10 mM/1 mL solution).

ENCOMPASS_PREFERRED
297

eMolecules​ 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 6mg | 564356415

Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 6mg | 564356415

ENCOMPASS_PREFERRED
298

Medchemexpress LLC Iccb-19 hydrochloride | 1803605-68-6 | 99.3% | 291.84 | 1 ML
SDP

ICCB-19 hydrochloride is an inhibitor of TRADD (TNFRSF1A associated via death domain). It binds to the N-terminal domain of TRADD (TRADD-N), which prevents TRADD-N from binding to both TRADD-C and TRAF2. ICCB-19 hydrochloride also acts as an indirect inhibitor of RIPK1 kinase activity and effectively induces autophagy and the degradation of long-lived proteins.

  • TRADD (TNFRSF1A associated via death domain) inhibitor.
  • Binds with N-terminal domain of TRADD (TRADD-N), disrupting its binding to both TRADD-C and TRAF2.
  • Indirect inhibitor of RIPK1 kinase activity.
  • Induces autophagy and degradation of long-lived proteins.
  • Inhibits Bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM (In Vitro).
  • Reduces inflammatory responses in Tradd-/- mice (In Vivo).

ENCOMPASS_PREFERRED
299

eMolecules​ 101-18-8 | 3-Hydroxydiphenylamine | Combi-Blocks | MFCD00002262 | 185.226 | C12H11NO | 98.000 | Oc1cccc(Nc2ccccc2)c1 | 1g | 290690778

3-Hydroxydiphenylamine | Combi-Blocks | 101-18-8 | MFCD00002262 | 185.226 | C12H11NO | 98.000 | Oc1cccc(Nc2ccccc2)c1 | 1g | 290690778

ENCOMPASS_PREFERRED
300

eMolecules​ 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 20mg | 564356420

Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 20mg | 564356420

ENCOMPASS_PREFERRED