Aminophenols
Apexbio Technology LLC BIOTIN-4-AMINOPHENOL-5MG
Biotin-4-aminophenol (CAS No 901770-40-9) is a chemical compound used in biomedical research originating from the field of biochemistry It operates primarily through biotinylation affecting pathways involved in cellular signaling and transport In vitro it demonstrates activity in the nanomolar to low micromolar range making it suitable for precise biological studies Typical applications include experiments in various cell models animal studies and drug screening processes where it serves as a critical reagent for labeling and tracking molecules Experimental concentrations typically depend on the specific research design allowing researchers to tailor its use to their particular study needs
Medchemexpress LLC BN82002 hydrochloride | 1049740-43-3 | 99.4% | 395.88 | 50 MG
BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. The compound demonstrates approximately 20-fold greater selectivity over CD45 tyrosine phosphatase and inhibits cell proliferation in several human tumor cell lines in a concentration-dependent manner in the low micromolar range. Treatment with 50 μM BN82002 modestly affects cell cycle distribution, suggesting cell cycle arrest at various stages.
- Potent, selective, and irreversible inhibitor of CDC25 phosphatase family.
- Displays approximately 20-fold greater selectivity over CD45 tyrosine phosphatase.
- Inhibits cell proliferation in various human tumor cell lines.
- For research use only.
Medchemexpress LLC SKI-178 | 1259484-97-3 | 99.29% | 100 MG
SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. It exhibits cytotoxicity at IC50 concentrations ranging from 0.1 to 1.8 μM in various cancer cell lines, including MTR3, NCI-ADR, and HL60/VCR cells. SKI-178 induces apoptosis in human acute myeloid leukemia cell lines in a CDK1-dependent manner and has been shown to inhibit leukemic progression in an MLL-AF9 mouse model.
- Potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2
- Exhibits cytotoxicity in multiple cancer cell lines
- Induces apoptosis in human acute myeloid leukemia cell lines
- Inhibits leukemic progression in MLL-AF9 mouse model
- Purity of 99.29%
- Soluble in DMSO for in vitro experiments
- Formulations suitable for oral and intraperitoneal injection for in vivo studies
Medchemexpress LLC Imiloxan hydrochloride | 81167-22-8 | 98.5% | 280.75 g/mol | C14H17ClN2O2 | 5 MG
Imiloxan hydrochloride is a potent, selective α2B-adrenoceptor antagonist used in pharmacological research to probe α2-adrenergic receptor subtype function. It is supplied as a characterized solid with defined purity and molecular weight for use in receptor-binding studies, in vitro assays, and in vivo experiments.
- Selective α2B-adrenoceptor antagonist
- High purity suitable for research applications
- Supplied in small research pack sizes for lab use
- Supported by analytical data (HNMR, LC-MS)
- Provided with SDS, COA, and handling instructions
Medchemexpress LLC DC-Chol hydrochloride | 166023-21-8 | >99.9% | 537.26 | 250 MG
DC-Chol hydrochloride is a cationic lipid that inhibits Aβ40 fibril formation and amyloidogenesis of oxidized hCT. It enhances the body's immune response to antigens by inducing the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. This compound is also utilized as a gene delivery vector.
- Can inhibit Aβ40 fibril formation
- Strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner
- Induces production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines
- Enhances the body's immune response to antigens
- Used as a gene delivery vector
- Can be used in research for hepatitis B vaccines to improve vaccine immunity
Medchemexpress LLC Scopine hydrochloride | 85700-55-6 | 99.7% | 5 MG
Scopine hydrochloride, also known by its synonym 6,7-Epoxytropine hydrochloride, is recognized as a metabolite of Scopolamine and functions as a brain-targeting compound. This compound has demonstrated the ability to significantly elevate the brain exposure of Chlorambucil and consequently amplify its anti-glioma activity. These properties make Scopine hydrochloride a candidate for targeted therapy research focused on brain gliomas.
- It is a metabolite of Scopolamine.
- It acts as a brain-targeting compound.
- It significantly increases the brain exposure of Chlorambucil.
- It enhances the anti-glioma activity of Chlorambucil.
- It is used in targeted therapy research for brain gliomas.
- CHLS (Scopine combined with Chlorambucil) exhibits significant anti-glioma activity in C6 cells.
- Its IC50 & target is the α adrenergic receptor.
Medchemexpress LLC Sotalol hydrochloride | 959-24-0 | 99.9% | 100 MG
Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker and a potent antiarrhythmic agent. It can be used for the research of pediatric arrhythmias and also functions as an antiepileptic agent.
- Blocks β-receptors
- Blocks potassium KCNH2 channels
- Suitable for research on pediatric arrhythmias
- Functions as an antiepileptic agent
Medchemexpress LLC ZM39923 hydrochloride | 1021868-92-7 | MFCD04974534 | 99.8% | 367.91 g/mol | C23H26ClNO | 5MG
ZM39923 hydrochloride is a research-grade small molecule that acts primarily as a JAK3 inhibitor (pIC50 = 7.1) and also potently inhibits tissue transglutaminase (TGM2) (IC50 ≈ 10 nM). It displays weaker activity against EGFR and JAK1 and minimal activity versus Lck and CDK4. Supplied as the hydrochloride salt with high reported purity, it is intended for laboratory research use only.
- JAK3 inhibitor with pIC50 7.1.
- Potent tissue transglutaminase (TGM2) inhibition (IC50 ≈ 10 nM).
- Hydrochloride salt form for improved stability and handling.
- High reported purity (around 99.8%).
- Available as solid and as a DMSO solution format.
- Intended for research use only; not for diagnostic or therapeutic use.
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 10 MG
Hypidone hydrochloride is the hydrochloride salt of a research compound reported to modulate 5-HT receptors and inhibit serotonin uptake in preclinical studies. It is supplied as a high-purity solid for laboratory use, typically in milligram-scale vials for in vitro and in vivo research.
- High reported purity (>99%).
- Molecular weight 334.84 g/mol.
- Solid hydrochloride salt, white to off-white powder.
- Reported activity as a 5-HT receptor modulator and uptake inhibitor in preclinical models.
- Packaged in small, milligram-scale quantities suitable for research.
eMolecules 74283-34-4 | 2,4-Diaminophenol sulfate | MFCD01321156 | 1g
Combi-Blocks, Inc. | 2,4-Diaminophenol sulfate | 1g | 603144863 | QC-1959 | 98.000 | 74283-34-4 | MFCD01321156 | 222.220 | C6H10N2O5S
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Medchemexpress LLC Axc-715 hydrochloride | 2490497-93-1 | 99.5% | C18H26ClN5 | 10MG
AXC-715 hydrochloride is the hydrochloride salt of a small-molecule TLR7/TLR8 dual agonist used for preclinical immunology and oncology research. Supplied for research use only, it is described as an immune adjuvant and has been used in synthesis of antibody-adjuvant conjugates and in vivo antitumor models.
- Dual TLR7/TLR8 agonist activity for immune-modulating studies
- High purity (99.5%) for reproducible experimental results
- Hydrochloride salt form improves aqueous solubility relative to the free base
- Suitable for conjugation and formulation in antibody-adjuvant constructs
- Available in small-scale research quantities for preclinical work
- Storage recommendations provided for solid and solution forms to maintain stability